FORMULATION OF EFFERVESCENT GRANULES FROM RED GINGER (ZINGIBERIS OFFICINALE ROSCOE VAR. RUBRUM) EXTRACT AND ITS ANTIOXIDANT ACTIVITY

Objective: Ginger is one of the Indonesian plants that has been used as traditional medicine. The flavonoids and phenols compounds contained high antioxidant activity. This study aimed to formulate effervescent granules (EG) from red ginger (RG) extract and evaluate its antioxidant activity. Methods: The formulation of EG from RG extract was prepared by the wet granulation method using different concentrations of polyvinylpyrrolidone (PVP). Furthermore, the flowability of granules was evaluated, including flow rate, angle of repose, bulk density, tapped density, Carr's index, Hausner ratio, and effervescent time. The physical stability of granules such as organoleptic evaluation, effervescent time, and pH measurement was also evaluated after 28 d of storage, and the antioxidant activity of EG from RG extract was determined using 1,1-diphenyl-2-picrylhydrazyl (DPPH). Results: The result showed that the EG of RG extract was successfully prepared by wet granulation with a concentration of 15%. In addition, the flowability study showed that all formulas of EG from RG extract have good flow properties, and the granules showed excellent flow properties based on Carr′s index results. The effervescent time of granules remained within the acceptable range according to USP, and the physical stability did not change even after 28 d of storage. The IC50 of EG from RG extract was 283.28±3.6 ppm and has moderate in free radicals scavenging activity. Conclusion: EG from RG extract can be used as food supplements to protect the human body from free radicals and inhibit oxidases.

Community Empowerment with Training in the Making of Spice Tea Beverages in Banjaragung Village, Tuban District

Community Service is one of the Tri dharmas of Higher Education to be one of the accesses to achieve this vision. The community in Banjaragung Village was chosen as a partner to introduce Health Tea drinks made from pure spices. Through this activity, the author hopes to be able to carry out the mission to realize the learning process in the field of creative economic entrepreneurship with qualities that are relevant to the needs of today's society. Spices and especially sappan wood in Banjaragung Village have not been processed properly and lacked innovation. Considering that today's society needs drinks and food that can increase the body's immune system with spices, community service is made to make training to process secang wood and spices such as red ginger, lemongrass, cinnamon and tea leaves into products that are quickly consumed. by making health tea bags. Secang wood plant or the Latin nameCaesalpinia sappan is one type of spice that can be used for its woody stems or fruit. The components of bioactive compounds contained inwood, namely brazilian, brazilein, 3'-O-methyl braziline, sappansappan, chalcone, sappancalchone are known as antioxidants. Research on sappan wood as an antioxidant and can be used as a natural dye has been a lot. The counseling carried out is expected to provide insight to the community in Banjaragung Village about how to make Health Tea drinks so that they can help improve the economic level of the community.

Separation of 6-Gingerol in Zingiber Officinale Rubrum Varieties Using an Ultrasonic Assisted Extraction Method

Gingerol is a chemical compound found in red ginger, with pharmaceutical use as an analgesic drug. Generally, gingerol separation in ginger uses the Soxhlet extraction method, but this process has a weakness. It requires a long process and unsatisfactory yield. This research aims to study ultrasonic frequency effect on increasing gingerol yield in the extraction process. The variables studied were extraction times with variations of 30, 60, 90, and 120 minutes. In addition, the ultrasonic effect was also observed with variations in the ultrasonic frequency of 40 and 50 kHz compared to the solvent extraction method. This study used 70% (v/v) ethanol as a solvent and an operating temperature of 50 ºC as fixed variables.Furthermore, it used a rotary vacuum evaporator at a pressure of 350 mmHg to separate the resulting gingerol extract. Qualitative sample analysis used Thin Layer Chromatography (TLC) and scanning electron microscope (SEM) while quantitative analysis used high-performance liquid chromatography (HPLC), Waters Alliance e2695 brand with X-Terra RP18 column 100 x 4.6 mm, five μm to determine the total gingerol extract. The results showed that ultrasonic power had a significant effect on the results obtained, with the highest yield was 24.71% at the ultrasonic frequency of 50 kHz with an extraction time of 120 minutes.

Response of Growth and Production of Red Ginger (Zingiber Officinale Rubrum Rosc.) to the Use of Compost as a Planting Media

Red ginger is a prima donna medicinal plant during this COVID-19 pandemic, because it can help the body's immunity. For this reason, a cultivation method that can increase production is needed. This study aims to see the effect of using compost on the production of red ginger plants. The study was conducted in April 2021 until it was completed. The results showed that the production of red ginger using oil palm empty fruit bunch compost media was higher than other compost media. Keywords: Production, Red Ginger, COVID-19.

MASSAGE EFFLURAGE USING RED GINGER EFFECTIVELY RELIEVES GOUT ARTHRITIS PAIN IN ELDERS

ABSTRACT BACKGROUND: Most elders with gout arthritis pain choose analgesic to deal with their pain. Massage efflurage using red ginger is a therapy to reduce gout arthritis pain. The objective of research was to find out the effectiveness of message efflurage using red ginger in relieving gout arthritis pain in elders. METHOD: The research design employed in this study was pre-experimental one group pre-posttest design. Independent variable was massage efflurage using red ginger and dependent variable was gout arthritis pain in elders. The population of research was all elders in Kedungbendo Village of Mojokerto Regency, consisted of 36 elders. The sample of research consisted of 33 elders taken using probability simple random sampling technique used. Pretest-posttest data were collected using numerical pain scale observation sheet. RESULT: The result of pretest-posttest obtained from 8 respondents with severe pain showed that their pain change into mild (5 respondents) and moderate pains (3). Out of 21 respondents, 9 respondents showed that their pain changed from moderate into no pain, 10 respondents into mild pain and 2 stable. Out of 4 respondents with mild pain, all of them showed that their pain changed into no pain. CONCLUSION: The result of Wilcoxon test showed 0.000 ≤ α= 0.05, meaning that there is an effective effect of massage efflurage using red ginger on the relief of gout arthritis pain in elders. This result indicated that massage efflurage using red ginger affected the gout arthritis pain scale in elders. Respondents are expected to reduce the consumption of analgesics and to switch to a safe alternative therapy to reduce negative effect related to aging process experienced by elders. Keywords: Gout Arthritis, Massage Efflurage, Red Ginger

Penerapan Kompres Hangat Menggunakan Jahe Merah Untuk Menurunkan Nyeri Pada Lansia Dengan Gout Arthtritis

Gout Arthtritis is a disease, often occurs in the elderly. The symptoms are swelling, redness, heat and pain at night. One of the ways to overcome the disorder is by warm compressing using red ginger. This study aims to apply warm compress using red ginger in reduding pain. To be known, it focused two elderly with gout arthtritis. The result shows by applying the technique, it reduced a pain scale in the fifth meeting. From the first client, it can reduce a pain scale of 9 to 2. Meanwhile, it can reduce a pain scale of 8 to 3 from the second one. The conclusion is the warm compress technique using red ginger could reduce a pain scale in the elderly with gout arthtritis. Therefore, it is expected to apply this technique regularly. Keywords: Gout arthtritis; Warm compress using red gingers; Elderly; Pain AbstrakGout arthtrtitis merupakan penyakit yang sering terjadi pada lansia. Gejala dari gout arthtrtitis itu sendiri yaitu terjadi pembengkakan, kemerahan, timbul rasa panas dan nyeri pada malam hari, untuk meringankan rasa sakit tersebut. Salah satu tindakan dengan terapi non farmakologi yang dapat dilakukan untuk menurunkan nyeri adalah teknik kompres hangat menggunakan jahe merah. Studi kasus ini bertujuan untuk menerapkan kompres hangat menggunakan jahe merah dalam menurunan nyeri. Fokus studi kasus yaitu pada 2 lansia dengan masalah gout arthritis. Hasil studi kasus menunjukkan teknik kompres hangat menggunakan jahe merah dapat menurunkan skala nyeri pada pertemuan ke 5. Klien pertama dari skala nyeri 9 menjadi 2, sedangkan klien yang kedua dari skala nyeri 8 menjadi 3. Kesimpulannya adalah bahwa teknik kompres hangat menggunakan jahe merah dapat menurunkan skala nyeri pada lansia dengan gout arthtritis. Saran bagi pasien untuk melakukan teknik kompres hangat menggunakan jahe merah dengan rutin dan teratur.Kata kunci : Gout Arthtritis; Kompres hangat jahe merah; Lansia; Nyeri

Pemberian Terapi Minyak Jahe Merah Dalam Mengurangi Intensitas Nyeri Sendi Pada Lansia

ABSTRAK Lansia merupakan populasi yang mayoritas memiliki masalah nyeri sendi. Proses penuaan dan penyakit penyerta membuat lansia mengalami nyeri sendi yang tidak dapat menggangu aktifitas harian dan pergerakan. Selama ini lansia mengatasi nyeri sendi dengan terapi famakologi atau terapi obat pengurang nyeri. Masih sedikit yang mengetahui bahwa terapi komplementer seperti jahe merah dapat membantu menguragi nyeri sendi. Jahe merah mempunyai kandungan minyak atsiri yang digunakan sebagai pengurang rasa nyeri. Tujuan kegiatan pengabdian masyarakat ini adalah mengidentifikasi efektifitas terapi jahe merah terhadap intensitas nyeri sendi pada lansia. Metode kegiatan pengabdian masyarakat ini adalah sosialisasi dan demonstrasi terapi minyak jahe merah pada lokasi nyeri sendi. Sebanyak 25 lansia berpartisipasi aktif dalam kegiatan ini. Sebelum terapi minyak jahe merah ditemukan 90 % lansia dengan instensitas nyeri 6-7 (nyeri berat). Setelah dilakukan terapi minyak jahe merah 95 % lansia dengan intensitas nyeri menjadi skala 4-5 (nyeri ringan). Hal ini menunjukan bahwa terapi minyak jahe merah efektif mengurangi intensitas nyeri sendi. Kesimpulan pemberian minyak jahe merah pada lansia dengan intensitas nyeri sendi merupakan salah satu terapi yang efektif untuk menurunkan intensitas nyeri sendi. Kata Kunci: Jahe Merah; Lansia; Nyeri ABSTRACT The elderly are the majority of the population with joint pain problems. The aging process and concomitant diseases make the elderly experience joint pain that cannot interfere with daily activities and movements. During this time the elderly overcome joint pain with pharmacology therapy or pain reduction drug therapy. Few know that complementary therapies such as red ginger can help reduce joint pain. Red ginger has an essential oil content that is used as a pain reduction. The purpose of this community service activity is to identify the effectiveness of red ginger therapy on the intensity of joint pain in the elderly. This method of community service activity is socialization and demonstration of red ginger oil therapy at the site of joint pain. A total of 25 seniors actively participated in this activity. Before red ginger oil therapy found 90 % elderly with pain intensity 6-7 (severe pain). After therapy red ginger oil 95 % elderly with pain intensity to a scale of 4-5 (mild pain). This indicates that red ginger oil therapy effectively reduces the intensity of joint pain. The conclusion of giving red ginger oil to the elderly with the intensity of joint pain is one of the effective therapies to lower the intensity of joint pain. Keyword: Red Ginger; Elderly; Pain

Effect of Red Ginger Essential Oil (Zingiber officinale Var. Rubrum) Addition on Chitosan Based Edible Coating towards Organoleptic Characteristics Pempek

This study aims to determine the best concentration of red ginger essential oil addition (Zingiber officinale var. Rubrum) edible coating to chitosan on the organoleptic quality of pempek. The research method was experimental which consisted of 5 treatments, namely control, addition of red ginger essential oil with concentrations of 0%, 0.5%, 1%, and 1.5% with 20 panelists as replicates. Parameters observed included organoleptic characteristics (appearance, texture, aroma, taste, tooth test, and folding test) based on the panelists' preference level using hedonic tests and chemical analysis (moisture content and fat content) and the shelf life of pempek. The data from the water content and fat content tests were analyzed descriptively, while the organoleptic test results were analyzed using non-parametric statistics with the test Friedman, if the test Friedman gave a rejection, multiple comparisons were performed and test was performed Bayes for decision making. The results showed that the best treatment in extending the shelf life of pempek was treatment D with the addition of 1% red ginger essential oil with a moisture content of 55.30% on the first day and 55.31% on the fourth day. While the fat content on the first day was 1.42% and on the fourth day it rose to 2.72% with the characteristics of appearance, texture, aroma, and taste still favored by the panelists.

PEMANFAATAN OBAT TRADISIONAL PENANGKAL PENULARAN COVID-19

In this time of the rampant Covid-19 pandemic, all recommended treatments and vaccines do not guarantee that you will be protected from the Covid-19 virus. Moreover, currently the positive rate of Covid-19 is very high in Indonesia so that people really need traditional medicines in dealing with the Covid-19 pandemic. Several researchers in Indonesia suggest traditional medicines that have been tested in the laboratory as an alternative in handling Covid-19, apart from being easy to find and cheap, traditional medicines are also believed to increase the body's immunity. Online media in Indonesia are also not a few who report about traditional medicines that are effective in handling Covid-19, social media is also a place for all information on traditional medicines. This article was created with the aim of making people aware of the benefits of good traditional medicines to increase body immunity. In this article, using normative legal research methods. Soerjono Soekanto and Sri Mamudji (2007) explains that in normative legal research, the basic data used are library materials which in research science are classified as secondary data. The results of this study show that: (1) the role of traditional medicine is very helpful for first aid during the Covid-19 pandemic; (2) factors supporting the body's immunity during the Covid-19 pandemic; (3) disease prevention and cure of minor ailments. Based on the results of this study, it can be concluded that traditional medicines such as garlic, ginger, honey, red ginger, turmeric, bitter, and several other herbal medicines can be focused on extraction to produce active compounds as Covid-19 immunomodulators.Masa pandemi Covid-19 yang sedang marak ini, sehingga segala pengobatan dan vaksin yang dianjurkan tidak menjamin akan terhindar dari virus Covid-19. Terlebih, sekarang ini tingkat angka positif Covid-19 sangat tinggi di Indonesia sehingga masyarakat sangat membutuhkan obat-obat tradisional dalam menghadapi pandemi Covid-19. Beberapa peneliti di Indonesia menyarankan obat-obat tradisional yang sudah teruji di laboratorium sebagai alternatif dalam penanganan Covid-19,alasannya selain karena mudah ditemukan dan murah, obat-obat tradisional juga dipercaya dapat meningkatkan imunitas tubuh. Media online di Indonesia juga tidak sedikit yang memberitakan tentang obat-obat tradisional yang ampuh dalam penanganan Covid-19, sosial media juga menjadi wadah untuk segala informasi obat-obat tradisional. Artikel ini dibuat dengan tujuan agar masyarakat mengetahui manfaat dari obat-obat tradisional yang bagus untuk meningkatkan imunitas tubuh. Dalam artikel ini, menggunakan metode penelitian hukum normatif yang berfokus pada data sekunder pengolahan dan analisis data dilakukan secara kualitatif dengan menggunakan logika deduktif .Obat tradisional sangat membantu untuk pertolongan pertama di masa pandemi Covid-19, faktor penunjang imunitas tubuh di masa pandemi Covid-19, pencegahan penyakit, dan penyembuhan penyakit yang ringan. Obat-obat tradisional seperti, bawang putih, temulawak, madu, jahe merah, kunyit, sambiloto, dan beberapa obat herbal lainnya dapat difokuskan untuk diekstraksi guna menghasilkan senyawa aktif sebagai pengatur sistem kekebalan tubuh Covid-19.