The article considers and describes in detail the peculiarities of teachers’ professional behavior. The authors determine its most specific and essential features, as well as its structure depending on the type of educational organization and region of residence. Besides, a significant part of the research is devoted to the consideration and comparison of teachers’ professional behavior characteristics depending on the level of occupational health disorders. The experimental study involved the teachers who implement inclusive education in the Northwestern Federal District of the Russian Federation (Kaliningrad and Vologda regions). Among them there are future teachers and secondary school teachers implementing inclusive practice, preschool and secondary school teachers working with the children with disabilities. The total amount of the participants was 1450 people, and the number of representative samples came up to 752 people. In the course of the study, the role of various factors in teachers’ professional behavior was revealed and updated: behavioral and environmental factors as well as personality traits. In order to maintain professional health of teachers, a psychological and pedagogical workshop was organized, which included educational and applied stages. In modular psychological and pedagogical support, the emphasis was made on health-saving technologies that contribute to professional burnout prevention, on the possibility of developing and applying relevant patterns of coping behavior in labor relationships.