The role of medications in successful aging

Climacteric ◽  
2021 ◽  
pp. 1-8
Author(s):  
R. D. Langer
Keyword(s):  
Successful Aging

Community-Led Ecosystem

2020 ◽  
pp. 29-47
Author(s):  
Elzbieta Bobrowicz-Campos ◽  
Filipa Costa Couto ◽  
Luísa Teixeira-Santos ◽  
João Apóstolo
Keyword(s):  
Decision Making ◽  
Successful Aging ◽  
Scaling Up ◽  
Informed Decision Making ◽  
Integrated Healthcare ◽  
Joint Actions ◽  
Current Health ◽  
Innovative Solutions ◽  
Healthcare Model

In this chapter, the triangulation analysis of connections between older adults, relevant stakeholders, and community will be made in order to acknowledge the challenges resulting from demographic changes, identify the gaps in current health and social policy in the field of geriatric care, and outline the pathways for joint actions to achieve successful aging. This analysis will also consider health and health equity drivers, highlighting the relevance of the community-led ecosystem in the spreading and scaling up of the person-centered and integrated healthcare model. By focusing on frailty and frailty-related consequences, this chapter will reflect on the need for implementing joint actions that promote health throughout the lifecycle and that empower citizens for informed decision making. It will also discuss the role of modern societies in creating innovative solutions for successful aging.

Older Adults’ Recalled Memorable Messages about Aging and Their Associations with Successful Aging

2019 ◽  
Vol 45 (4) ◽  
pp. 474-507 ◽  
Author(s):  
Quinten S Bernhold ◽  
Howard Giles
Keyword(s):  
Older Adults ◽  
Successful Aging ◽  
Hope Theory ◽  
Memorable Messages ◽  
Subjective State ◽  
Age Related ◽  
Dispositional Hope ◽  
The Right ◽  
Memorable Message

Abstract Using the Communicative Ecology Model of Successful Aging (CEMSA), this study examined how one’s own age-related communication and memorable message characteristics indirectly predict successful aging, via aging efficacy. Older adults with higher dispositional hope recalled memorable messages as (a) higher in positivity, (b) higher in efficacy, and (c) more likely to contain a theme of aging not being important or being a subjective state that can be overcome with the right mindset. Older adults were classified as engaged, bantering, or disengaged agers, based on their own age-related communication. Uniquely for CEMSA’s development and the blended role of hope theory within it, memorable message efficacy indirectly predicted greater successful aging, via heightened aging efficacy.

scholarly journals CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging

2019 ◽  
Vol 75 (9) ◽  
pp. 1618-1623 ◽  
Author(s):  
Ana Kolicheski ◽  
Ronald L Walton ◽  
Alexandra I Soto-Beasley ◽  
Michael G Heckman ◽  
Ryan J Uitti ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Neurodegenerative Disease ◽  
Neurological Disease ◽  
Successful Aging ◽  
Snp Array ◽  
Missense Variant ◽  
Caucasian Population ◽  
Healthy Individuals ◽  
Specific Subset

Abstract A number of efforts are underway to better understand the role of genetic variation in successful aging and longevity. However, to date, only two genes have been consistently associated with longevity in humans: APOE and FOXO3, with the APOE ɛ2 allele also protective against dementia. Recently, using an exome-wide SNP array approach, a missense variant CLEC3B c.316G>A (rs13963 p.S106G) was reported to associate with longevity in two independent cohorts of Japanese and Chinese participants. Interestingly, CLEC3B p.S106G is more frequent in Caucasian populations. Herein, we examined the frequency of CLEC3B p.S106G in a Caucasian series of 1,483 neurologically healthy individuals with a specific subset >80 years of age. Although our findings do not support an association between CLEC3B p.S106G and aging without neurological disease (p = .89), we confirmed the association between the APOE ε2 allele and better survival without neurological disease (p = .001). Further assessment of healthy aged cohorts that retain intact neurological function will be critical to understand the etiology of neurodegenerative disease and the role of age at risk.

Physical activity as a protective factor for successful aging

2019 ◽  
Vol 29 (87) ◽  
pp. 47-52
Author(s):  
Andrzej Jopkiewicz ◽  
Monika Królicka–Czerniak ◽  
Anita Zaręba
Keyword(s):  
Physical Activity ◽  
Prefrontal Cortex ◽  
Cognitive Processes ◽  
Cognitive Aging ◽  
Successful Aging ◽  
Protective Factor ◽  
Protective Role ◽  
Factors Affecting ◽  
The Brain

To divide the types of aging (successful, usual and impaired), as well as factors affecting this process, the protective role of physical activity was discussed in the literature. It was emphasized that physical activity is also a very important protective factor for cognitive aging - mainly executive function and memory. The prefrontal cortex and hippocampus, i.e. the regions of the brain responsible for the control and course of cognitive processes, show susceptibility to stimulation, which is movement exercises, which are prevention of degenerative changes within the brain.

scholarly journals The Role of the Mitochondrial Genome in Ageing and Carcinogenesis

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Anna M. Czarnecka ◽  
Ewa Bartnik
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Genome ◽  
Cancer Cells ◽  
Successful Aging ◽  
Mitochondrial Haplogroups ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations

Mitochondrial DNA mutations and polymorphisms have been the focus of intensive investigations for well over a decade in an attempt to understand how they affect fundamental processes such as cancer and aging. Initial interest in mutations occurring in mitochondrial DNA of cancer cells diminished when most were found to be the same mutations which occurred during the evolution of human mitochondrial haplogroups. However, increasingly correlations are being found between various mitochondrial haplogroups and susceptibility to cancer or diseases in some cases and successful aging in others.

The Role of Energy Balance in Successful Aging Among Elderly Individuals

2015 ◽  
Vol 27 (8) ◽  
pp. 1375-1391 ◽  
Author(s):  
Stefanos Tyrovolas ◽  
Josep Maria Haro ◽  
Anargiros Mariolis ◽  
Suzanne Piscopo ◽  
Giuseppe Valacchi ◽  
...  
Keyword(s):  
Energy Balance ◽  
Successful Aging ◽  
Elderly Individuals

scholarly journals Ego and Spiritual Transcendence: Relevance to Psychological Resilience and the Role of Age

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Barbara Hanfstingl
Keyword(s):  
Meaning In Life ◽  
Successful Aging ◽  
Spiritual Experience ◽  
Psychological Resilience ◽  
Loss Of Control ◽  
Theoretical Assumption ◽  
Spiritual Transcendence ◽  
Age Related ◽  
The One

The paper investigates different approaches of transcendence in the sense of spiritual experience as predictors for general psychological resilience. This issue is based on the theoretical assumption that resilience does play a role for physical health. Furthermore, there is a lack of empirical evidence about the extent to which spirituality does play a role for resilience. As potential predictors for resilience, ego transcendence, spiritual transcendence, and meaning in life were measured in a sample of 265 people. The main result of a multiple regression analysis is that, in the subsample with people below 29 years, only one rather secular scale that is associated with ego transcendence predicts resilience, whereas for the older subsample of 29 years and above, spiritual transcendence gains both a positive (oneness and timelessness) and a negative (spiritual insight) relevance to psychological resilience. On the one hand, these results concur with previous studies that also found age-related differences. On the other hand, it is surprising that the MOS spiritual insight predicts psychological resilience negatively, the effect is increasing with age. One possible explanation concerns wisdom research. Here, an adaptive way of dealing with the age-related loss of control is assumed to be relevant to successful aging.

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