scholarly journals An evaluation of the anti-inflammatory, antipyretic and analgesic effects of hydroethanol leaf extract of Albizia zygia in animal models

2016 ◽  
Vol 55 (1) ◽  
pp. 338-348 ◽  
Author(s):  
Wonder Kofi Mensah Abotsi ◽  
Stanley Benjamin Lamptey ◽  
Stephen Afrane ◽  
Eric Boakye-Gyasi ◽  
Ruth Uwa Umoh ◽  
...  
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Analgesic Effects ◽  
Anti Inflammatory

scholarly journals Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models

2018 ◽  
Vol 9 ◽  
Author(s):  
Mansour Sobeh ◽  
Mona F. Mahmoud ◽  
Ganna Petruk ◽  
Samar Rezq ◽  
Mohamed L. Ashour ◽  
...  
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Anti Inflammatory

scholarly journals Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents

2019 ◽  
Vol 65 (3) ◽  
pp. 22-31
Author(s):  
Ighodaro Igbe ◽  
Osaze Edosuyi ◽  
Agbonlahor Okhuarobo ◽  
Adarki Pongri ◽  
Nkechi Maduako ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Analgesic Effect ◽  
Leaf Extract ◽  
Methanol Extract ◽  
Tail Flick ◽  
Hot Plate ◽  
Analgesic Effects ◽  
Paw Oedema ◽  
Anti Inflammatory ◽  
Ear Oedema

Summary Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa. Various parts of the plant are used for the treatment of a variety of ailments in ethno-medicine. Objective: To evaluate the anti-inflammatory and analgesic effect of the methanol leaf extract of Cussonia barteri. Material and methods: The leaves were air-dried, powdered and repeatedly extracted with methanol using a Soxhlet apparatus. The resulting methanol extract (100, 200 and 400 mg/kg) was evaluated for anti-inflammatory activity using carrageenan-induced paw oedema, xylene-induced ear oedema and formalin-induced arthritis tests. Analgesic effect was evaluated using acetic acid-induced mouse writhing, hot plate and tail flick tests. Results: All doses of the extract significantly (p<0.05) reduced carrageenan-induced paw oedema, however the 400 mg/kg dose gave a sustained effect. The extract significantly inhibited xylene induced ear oedema at all doses. There were no significant (p>0.05) reductions in paw swellings due to formalin. In the acetic acid induced writhing test, the extract significantly (p<0.05) decreased writhing at 400 mg/kg only. Reaction times were not significantly different from the control in the hot plate and tail flick tests. Conclusion: This study has shown that the methanol extract possesses acute anti-inflammatory and peripherally mediated analgesic effects.

scholarly journals Analgesic, anti-inflammatory and antipyretic activities of ethanol extract of Annona senegalensis leaves in experimental animal models

2020 ◽  
Vol 9 (10) ◽  
pp. 1477
Author(s):  
Anthony U. Megwas ◽  
Godwin C. Akuodor ◽  
Leo C. Chukwu ◽  
Daniel O. Aja ◽  
Edmund M. Okorie ◽  
...  
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Therapeutic Potential ◽  
Ethanol Extract ◽  
Tail Flick ◽  
Experimental Animal Models ◽  
Antipyretic Activity ◽  
Egg Albumen ◽  
Anti Inflammatory ◽  
Abdominal Constriction

Background: This study was carried out to establish the analgesic, anti-inflammatory and antipyretic effects of the ethanol extract of Anonna senegalensis leaves in experimental animals.Methods: The analgesic activity was measured using the abdominal constriction and tail flick tests. The anti-inflammatory activity was performed using xylene and egg-albumen paw induced tests, while the antipyretic activity was measured using brewer’s yeast and 2, 4 dinitrophenol induced pyrexia tests, respectively.Results: The leaf extract at all doses used exhibited significant (p<0.05) analgesic, anti-inflammatory and antipyretic activities.Conclusions: Results show that ethanol leaf extract of Anonna senegalensis possess therapeutic potential against pains and feverish conditions, supporting the claims of its this plant as remedy for similar ailments.

Evaluation of the analgesic, anti-inflammatory, anti-oxidant, phytochemical and toxicological properties of the methanolic leaf extract of commercially processed Moringa oleifera in some laboratory animals

2015 ◽  
Vol 26 (5) ◽  
Author(s):  
Adeolu Alex Adedapo ◽  
Olufunke Olubunmi Falayi ◽  
Ademola Adetokunbo Oyagbemi
Keyword(s):  
Leaf Extract ◽  
Moringa Oleifera ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Laboratory Animals ◽  
Phytochemical Analysis ◽  
Writhing Test ◽  
Analgesic Effects ◽  
Anti Oxidant ◽  
Anti Inflammatory

AbstractThe commercially processedThe phytochemical analysis showed that the extract contained flavonoids, terpenoids, glycosides, tannins and saponins. In the acetic acid-induced writhing test, the extract significantly reduced the number of writhes at 100 and 200 mg/kg but not so much at 50 mg/kg. In the formalin-induced paw lick test, the effect was similar to that of the acetic writhing test. The analgesic effects were comparable to that of indomethacin used at 10 mg/kg. In the anti-inflammatory test, the extract reduced the formation of oedema especially at a dose of 200 mg/kg. In the anti-oxidant test, the extract was found to possess a free radical-scavenging property and is concentration related.The use of this extract for medicinal and nutritional purposes may have thus been justified; however, caution must be exercised in its use to prevent the toxic effect.

scholarly journals Musanga cecropioides leaf extract exhibits anti-inflammatory and anti-nociceptive activities in animal models

2015 ◽  
Vol 25 (5) ◽  
pp. 506-512 ◽  
Author(s):  
Abimbola Sowemimo ◽  
Eboji Okwuchuku ◽  
Fageyinbo Muyiwa Samuel ◽  
Olowokudejo Ayoola ◽  
Ibrahim Mutiat
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Anti Inflammatory

Anti-inflammatory and analgesic effects of Careya arborea stem bark in experimental animal models

2006 ◽  
Vol 9 (1) ◽  
Author(s):  
R Sambathkumar ◽  
T Sivakumar ◽  
R Shanmuga Sundaram ◽  
P Sivakumar ◽  
R Nethaji ◽  
...  
Keyword(s):  
Animal Models ◽  
Experimental Animal ◽  
Stem Bark ◽  
Experimental Animal Models ◽  
Analgesic Effects ◽  
Anti Inflammatory

scholarly journals Phytochemical Screening and Anti-Inflammatory Activities of Methanolic Leaf Extract of Bauhinia monandra in Animal Models

2018 ◽  
Vol 11 ◽  
pp. 7-16
Author(s):  
Augustine Nkemakolam Okorie ◽  
Kelechi Martins Nworie
Keyword(s):  
Animal Models ◽  
Topical Application ◽  
Leaf Extract ◽  
Methanol Extract ◽  
Therapeutic Potential ◽  
Phytochemical Screening ◽  
Paw Edema ◽  
Egg Albumin ◽  
Ear Edema ◽  
Anti Inflammatory

The leaves of Bauhinia monandra prepared as poultices are used in many Brazilian tribes and some Nigerian communities to relieve swelling and pains, arthritis, diabetes among other ailments. These folkloric claimed benefits inspired this study in which topical and systemic anti-inflammatory activities of a methanol extract of B. monandra leaves (MEBmL) was assessed in rodents. The anti-inflammatory activities of B. monandra were determined by egg albumin-induced (systemic) paw edema in rats, and xylene-induced (topical) ear edema in mice. Treatment of rats with MEBmL at different concentration (200 and 400 mg/kg) led to significant (p<0,05) reduction (31.0% and 28.0% respectively) of the egg albumin-induced paw edema. Topical application of mice ear with MEBmL (50, 100 mg/kg) also significantly (p<0.05) reduced (39.50% and 41.87% respectively) xylene-induced ear edema. Based on the findings of the study, B. monandra has a promising therapeutic potential with its anti-inflammatory activities as associated with folkloric use of the plant.

Sign in / Sign up

Export Citation Format

Share Document