Public policy is increasingly confounded by transnational policy challenges. The proliferation of global policy dilemmas—climate change, migration, terrorism, economic instability, and so on—diminishes state-level officials’ capacity to deliver local policy outcomes without some form of international collaboration. Yet it is becoming increasingly apparent that international organizations are not always equipped, politically or organizationally, to offer the necessary collaborative mechanisms to tackle many of these challenges. This chapter explores this emergent ‘global–local dilemma’ and questions how policy officials reconcile international and domestic imperatives in managing modern transnational policy challenges. To do so, this chapter examines the rise of transnational policy networks in the Anglosphere. Using interview and policy data, the concerted efforts of Anglosphere civil servants to overcome the global–local dilemma through collaboration and cooperation is revealed, through which insights are generated into how domestic officials interact in the international domain.