Activity of Adenosine Deaminase and Adenylate Deaminase on Adenosine and 2', 3'-Isopropylidene Adenosine: Role of the Protecting Group at Different pH Values

2008 ◽  
Vol 27 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Laura Alessandrini ◽  
Pierangela Ciuffreda ◽  
Radmila Pavlovic ◽  
Enzo Santaniello
Urology ◽  
2015 ◽  
Vol 86 (4) ◽  
pp. 730-734
Author(s):  
Amir Fattahi ◽  
Iraj Khodadadi ◽  
Iraj Amiri ◽  
Zeinab Latifi ◽  
Marzieh Ghorbani ◽  
...  

2010 ◽  
Vol 39 (10) ◽  
pp. 2262-2267 ◽  
Author(s):  
Raul Franzolin ◽  
Burk A. Dehority

In order to study the effect of pH on defaunation in the rumen, four rumen fistulated steers were fed a basal roughage diet for a 4-week adaptation period followed by 17 weeks of feeding with three diets and two feeding levels of high concentrate diet. Rumen outflow fluid rate was evaluated in both ration levels. Rumen protozoa population was monitored weekly and when animals became defaunated, protozoa were reinoculated with rumen contents from one of the faunated steers. At every two weeks, during all the experimental period, rumen pH was measured in all animals at 0, 4, 8 and 12 h after feeding. It was observed an individual animal influence on the establishment and maintenance of the rumen ciliate protozoa population. In all sampling times, mean rumen pH values were higher in faunated steers than in the defaunated ones. No differences were observed in rumen outflow fluid rates between the two ration levels. Extended periods of low rumen pH are probably more detrimental to the survival of ciliate protozoa in the rumen than other factors.


1992 ◽  
Vol 263 (4) ◽  
pp. G487-G493 ◽  
Author(s):  
D. R. Sawmiller ◽  
C. C. Chou

The role of adenosine in postprandial jejunal hyperemia was investigated by determining the effect of placement of predigested food into the jejunal lumen on blood flow and oxygen consumption before and during intra-arterial infusion of dipyridamole (1.5 microM arterial concn) or adenosine deaminase (9 U/ml arterial concn) in anesthetized dogs. Neither drug significantly altered resting jejunal blood flow and oxygen consumption. Before dipyridamole or deaminase, food placement increased blood flow by 30-36%, 26-42%, and 21-46%, and oxygen consumption by 13-22%, 21-22%, and 26-29%, during 0- to 3-, 4- to 7-, and 8- to 11-min placement periods, respectively. Adenosine deaminase abolished the entire 11-min hyperemia, whereas dipyridamole significantly enhanced the initial 7-min hyperemia (45-49%). Both drugs abolished the initial 7-min food-induced increase in oxygen consumption. Dipyridamole attenuated (14%), whereas deaminase did not alter (28%), the increased oxygen consumption that occurred at 8-11 min. Adenosine deaminase also prevented the food-induced increase in venoarterial adenosine concentration difference. In separate series of experiments, luminal placement of food significantly increased jejunal lymphatic adenosine concentration and release. Also, reactive hyperemia was accompanied by an increase in venous adenosine concentration and release. This study provides further evidence to support the thesis that adenosine plays a role in postprandial and reactive hyperemia in the canine jejunum.


BioResources ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. 4591-4635
Author(s):  
Martin A. Hubbe ◽  
Douglas S. McLean ◽  
Karen R. Stack ◽  
Xiaomin Lu ◽  
Anders Strand ◽  
...  

This review article considers the role of fatty acids and the mutual association of their long-chain (e.g. C18) alkyl and alkenyl groups in some important aspects of papermaking. In particular, published findings suggest that interactions involving fatty acids present as condensed monolayer films can play a controlling role in pitch deposition problems. Self-association among the tails of fatty acids and their soaps also helps to explain some puzzling aspects of hydrophobic sizing of paper. When fatty acids and their soaps are present as monolayers in papermaking systems, the pH values associated with their dissociation, i.e. their pKa values, tend to be strongly shifted. Mutual association also appears to favor non-equilibrium multilayer structures that are tacky and insoluble, possibly serving as a nucleus for deposition of wood extractives, such, as resins and triglyceride fats, in pulp and paper systems.


Author(s):  
Hiroyuki Ohta ◽  
Risa Tamura ◽  
Masashi Arake ◽  
Yuji Morimoto ◽  
Toshiaki Ishizuka

2020 ◽  
Vol 11 (4) ◽  
pp. 7990-7993
Author(s):  
Sangeetha R ◽  
Ramesh Raju K A P ◽  
Hemapriya S ◽  
Suganthi V ◽  
Panneerselvam P

Rheumatoid arthritis (RA) is a chronic disease that causes inflammatory synovitis. The treatment plan of RA includes reducing inflammation and improving the quality of life. Hence, understanding the role of Adenosine deaminase (ADA) and C-reactive protein helps for a better plan of treatment. The present study was undertaken to determine the serum ADA activity and CRP in RA patients and correlate with the severity of the progression of the disease. 25 patients diagnosed with RA as per 2010 ACR/EULAR criteria and 25 age and sex matched healthy controls were included in the study after informed consent. Blood samples were collected from all the subjects after an overnight fast, serum separated was analyzed immediately for Adenosine deaminase(ADA) activity measured using colorimetric method of Guisti and Galanti. Disease score, C-reactive protein, RA factor, ADA and ESR were significantly higher in cases when compared with controls. Significant positive correlation was present between the disease score and C-reactive protein, RA factor among cases. A positive correlation was observed between the disease score and ADA, but it was not statistically significant among cases.


1981 ◽  
Vol 94 (1) ◽  
pp. 269-274 ◽  
Author(s):  
R. P. HENRY ◽  
G. A. KORMANIK ◽  
N. J. SMATRESK ◽  
J. N. CAMERON

Blood calcium concentrations are elevated during a hypercapnic acidosis in the terrestrial crab Gecarcinus lateralis, but not in the aquatic Callincetes sapidus. The increase occurs concomitantly with a rise in blood HCO3- and partial restoration of resting blood pH values. It is believed that in G. lateralis that a source of CaCO3, possibly the shell, is being dissolved for buffering purposes.


Sign in / Sign up

Export Citation Format

Share Document