Thymidine Kinase 1 is a Potential Marker for Prognosis and Monitoring the Response to Treatment of Patients with Breast, Lung, and Esophageal Cancer and Non-Hodgkin's Lymphoma

2010 ◽  
Vol 29 (4-6) ◽  
pp. 352-358 ◽  
Author(s):  
E. He ◽  
X. H. Xu ◽  
H. Guan ◽  
Y. Chen ◽  
Z. H. Chen ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Thymidine Kinase ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Response To Treatment ◽  
Thymidine Kinase 1 ◽  
Non Hodgkin’S Lymphoma ◽  
Potential Marker ◽  
Non Hodgkin's Lymphoma

scholarly journals Non Hodgkin’s Lymphoma Presenting with Urticarial Vasculitis - A Rare Association

1970 ◽  
Vol 29 (1) ◽  
pp. 41-43
Author(s):  
N Puri ◽  
SK Malhotra
Keyword(s):  
Hodgkin’S Lymphoma ◽  
Hematological Malignancy ◽  
Hodgkin's Lymphoma ◽  
Response To Treatment ◽  
Urticarial Vasculitis ◽  
Old Patients ◽  
Rare Association ◽  
Key Words Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma

Urticarial vasculitis (UV) has been described as a rare association with hematological malignancy. We report the case of a 52 year old patients of localized B-cell non- Hodgkin’s lymphoma who presented with a recurrent nonpainful urticarial type rash distributed around his face, arms, forearms, buttocks and lower legs since 1 year. The patient was managed by intensive combination chemotherapy (CHOP) regime for several cycles. The patient showed good response to treatment. The case is being reported because of the rare association of Non Hodgkin’s lymphoma with urticarial vasculitis. Key Words: Lymphoma; lymphadenopathy; chemotherapy; bone marrow; lymphoid; cutaneous; histology. DOI: 10.3329/jbsp.v29i1.7170J Bangladesh Coll Phys Surg 2011; 29:41-43

scholarly journals Prognostic relevance of thymidine kinase isozymes in adult non- Hodgkin's lymphoma

Blood ◽  
1981 ◽  
Vol 58 (5) ◽  
pp. 926-930 ◽  
Author(s):  
PH Ellims ◽  
T Eng Gan ◽  
G Medley ◽  
MB Van Der Weyden
Keyword(s):  
Thymidine Kinase ◽  
Peripheral Blood ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Current Therapy ◽  
Therapeutic Approaches ◽  
New Therapeutic Approaches ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Peripheral Blood Plasma

Abstract To determine whether kinase (TK) isozyme status adds clinically useful information in adult non-Hodgkin's lymphoma (NHL), we have analyzed peripheral blood plasma and lymphocytes of 44 patients with NHL for either TK1 or TK2 isozyme activity. On the basis of isozyme status, patients could be divided into two groups that did not differ significantly with respect to known determinants for survival. The median survival of patients exhibiting peripheral blood TK1 thymidine kinase activity was 40 wk and that of individuals with TK2 activity was in excess of 200 wk. These data suggest that peripheral blood TK1 isozyme is a useful independent biochemical marker for a subgroup of NHL who respond poorly to current therapy and thus require new therapeutic approaches.

scholarly journals Prognostic relevance of thymidine kinase isozymes in adult non- Hodgkin's lymphoma

Blood ◽  
1981 ◽  
Vol 58 (5) ◽  
pp. 926-930 ◽  
Author(s):  
PH Ellims ◽  
T Eng Gan ◽  
G Medley ◽  
MB Van Der Weyden
Keyword(s):  
Thymidine Kinase ◽  
Peripheral Blood ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Current Therapy ◽  
Therapeutic Approaches ◽  
New Therapeutic Approaches ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Peripheral Blood Plasma

To determine whether kinase (TK) isozyme status adds clinically useful information in adult non-Hodgkin's lymphoma (NHL), we have analyzed peripheral blood plasma and lymphocytes of 44 patients with NHL for either TK1 or TK2 isozyme activity. On the basis of isozyme status, patients could be divided into two groups that did not differ significantly with respect to known determinants for survival. The median survival of patients exhibiting peripheral blood TK1 thymidine kinase activity was 40 wk and that of individuals with TK2 activity was in excess of 200 wk. These data suggest that peripheral blood TK1 isozyme is a useful independent biochemical marker for a subgroup of NHL who respond poorly to current therapy and thus require new therapeutic approaches.

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