Biomarker Measurements of Prenatal Exposure to Polychlorinated Biphenyls (Pcb) in Umbilical Cord Blood from Postpartum Hispanic Women in Brownsville, Texas

2013 ◽  
Vol 76 (22) ◽  
pp. 1225-1235 ◽  
Author(s):  
Ken Sexton ◽  
Jennifer J. Salinas ◽  
Thomas J. McDonald ◽  
Rose M. Z. Gowen ◽  
Rebecca P. Miller ◽  
...  
2016 ◽  
Vol 24 (1) ◽  
pp. 70-76
Author(s):  
Marilene Danieli Simões Dutra ◽  
Marcia Cavadas ◽  
Iracina Maura de Jesus ◽  
Elisabeth Oliveira Santos ◽  
Volney de Magalhães Câmara

Abstract Objective: to assess the central auditory processing of children exposed to mercury during the prenatal period. Design/Study sample: this study evaluated 90 children age eight to ten years, of both genders divided into two groups according to the levels of mercury exposure during the prenatal period: the study group (SG) was composed of children who had total mercury levels in umbilical cord blood samples equal or higher than 8µg/L, and the control group (CG) of children who had Mercury levels lower than 8µg/L. The procedures included a questionnaire, tonal threshold audiometry, word recognition audiometry, tests that assess auditory processing skills; and analysis of the total levels of mercury in umbilical cord blood samples collected at birth. Result: The SG presented mean total mercury in umbilical cord blood of 19.36µg/L and the CG had mean of 4.78µg/L. Regarding the tests that assess central auditory processing, the SG showed worse performance than the CG, and there was a statistically significant difference observed in the Staggered Spondaic Word Test. Conclusion: Children presented disorders in the tests that assess central auditory processing, indicating a possible effect of prenatal exposure to mercury in the central auditory system.


2013 ◽  
Vol 182 ◽  
pp. 63-69 ◽  
Author(s):  
Xijin Xu ◽  
Taofeek Akangbe Yekeen ◽  
Qiongna Xiao ◽  
Yuangping Wang ◽  
Fangfang Lu ◽  
...  

2019 ◽  
Vol 19 (6) ◽  
Author(s):  
Jihyun Kim ◽  
Seonwoo Kim ◽  
Sook-young Woo ◽  
Jin-Yong Chung ◽  
Young-Seoub Hong ◽  
...  

2021 ◽  
Author(s):  
Monica Seefelder de Assis Araujo ◽  
Nataly Damasceno de figueiredo ◽  
Jorge Fonte de Rezende Flho ◽  
Joffre Amim Junior ◽  
Marlos Melo Martins ◽  
...  

Abstract The PIPA Project is a prospective birth cohort study based in Rio de Janeiro, Brazil, whose pilot study was carried out between October 2017 and August 2018. Arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg) concentrations were determined in maternal (n = 49) and umbilical cord blood (n = 46). The Denver Developmental Screening Test II (DDST-II) was applied in 50 six-month-old infants. Metals were detected in 100% of the mother and newborn samples above the limits of detection. Maternal blood lead concentrations were higher in premature newborns (GM: 5.72 µg/dL; p = 0.05). One-third of the infants (17–33%) exhibited at least one fail in the neurodevelopment evaluation (fail group). Maternal blood arsenic concentrations were significantly (p = 0.02) higher in the "fail group" (GM: 11.85 µg /L) compared to infants who did not fail (not fail group) (GM: 8.46 µg /L). Maternal and umbilical cord blood arsenic concentrations were higher in all Denver Test’s domains (except personal/social) in the “fail group”, albeit non-statistically significant. These findings indicate the need to further investigate the toxic effects of prenatal exposure to metals on infant neurodevelopment.


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