Validation and quantification of neonicotinoid insecticide residues in rice whole grain and rice straw using LC-MS/MS

A green, simple and sensitive hydrophobic DES-based dispersive liquid–liquid microextraction coupled with high-performance liquid chromatography (HPLC) was developed for the analysis of neonicotinoid insecticide residues in various samples. A hydrophobic deep eutectic solvent (DES) was synthesized using decanoic acid as a hydrogen bond donor and tetrabutylammonium bromide (TBABr) as a hydrogen bond-acceptor. DESs were synthesized and characterized by Fourier transform-infrared (FTIR) spectroscopy. Two disperser solvents were substituted with surfactants and acetonitrile, which could afford more effective emulsification and make the extraction relatively greener. The hydrophobic DES extraction phase occurred 10 min after centrifugation, being easy to be collected for analysis. Several parameters were investigated and optimized. Under the optimum condition, the calibration curve of this method was linear in the range of 0.003–1.0-µg·mL−1, with a correlation coefficient (R2) higher than 0.99 and a good repeatability, with the relative standard deviations (RSDs) were less than 5.00%. The limits of detection were in the range of 0.001–0.003 µg·mL−1; the limits of quantitation were in the range of 0.003–0.009 µg·mL·mL−1. Finally, the presented method was implemented to determine the neonicotinoid insecticide residues in water, soil, egg yolk samples and acceptable recoveries were obtained.

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Neonicotinoid Insecticide Residues in Surface Water and Soil Associated with Commercial Maize (Corn) Fields in Southwestern Ontario

PLoS ONE ◽

10.1371/journal.pone.0118139 ◽

2015 ◽

Vol 10 (2) ◽

pp. e0118139 ◽

Cited By ~ 106

Author(s):

Arthur Schaafsma ◽

Victor Limay-Rios ◽

Tracey Baute ◽

Jocelyn Smith ◽

Yingen Xue

Keyword(s):

Surface Water ◽

Insecticide Residues ◽

Neonicotinoid Insecticide ◽

Corn Fields

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Application of the QuEChERS procedure and LC–MS/MS for the assessment of neonicotinoid insecticide residues in cocoa beans and shells

Journal of Food Composition and Analysis ◽

10.1016/j.jfca.2015.09.002 ◽

2015 ◽

Vol 44 ◽

pp. 149-157 ◽

Cited By ~ 21

Author(s):

Enock Dankyi ◽

Derick Carboo ◽

Chris Gordon ◽

Inge S. Fomsgaard

Keyword(s):

Cocoa Beans ◽

Insecticide Residues ◽

Neonicotinoid Insecticide

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Quantification of neonicotinoid insecticide residues in soils from cocoa plantations using a QuEChERS extraction procedure and LC-MS/MS

The Science of The Total Environment ◽

10.1016/j.scitotenv.2014.08.051 ◽

2014 ◽

Vol 499 ◽

pp. 276-283 ◽

Cited By ~ 48

Author(s):

Enock Dankyi ◽

Christopher Gordon ◽

Derick Carboo ◽

Inge S. Fomsgaard

Keyword(s):

Extraction Procedure ◽

Insecticide Residues ◽

Neonicotinoid Insecticide

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In-Situ Formation of Modified Nickel–Zinc-Layered Double Hydroxide Followed by HPLC Determination of Neonicotinoid Insecticide Residues

Molecules ◽

10.3390/molecules27010043 ◽

2021 ◽

Vol 27 (1) ◽

pp. 43

Author(s):

Jitlada Vichapong ◽

Rawikan Kachangoon ◽

Rodjana Burakham ◽

Yanawath Santaladchaiyakit ◽

Supalax Srijaranai

Keyword(s):

Limit Of Detection ◽

Sodium Dodecyl ◽

The European Union ◽

Precipitate Phase ◽

Insecticide Residues ◽

Nickel Zinc ◽

Neonicotinoid Insecticide ◽

In Situ Formation

A single-step preconcentration procedure using the in-situ formation of modified nickel–zinc-layered double hydroxides (LDHs) prior to high-performance liquid chromatography (HPLC) is investigated for the determination of neonicotinoid insecticide residues in honey samples. The LDHs could be prepared by the sequential addition of sodium hydroxide, sodium dodecyl sulfate, nickel nitrate 6-hydrate and zinc nitrate 6-hydrate, which were added to the sample solution. The co-precipitate phase and phase separation were obtained by centrifugation, and then the precipitate phase was dissolved in formic acid (concentrate) prior to HPLC analysis. Various analytical parameters affecting extraction efficiency were studied, and the characterization of the LDHs phase was performed using Fourier-transformed infrared spectroscopy and scanning electron microscopy. Under optimum conditions, the limit of detection of the studied neonicotinoids, in real samples, were 30 μg L−1, for all analytes, lower than the maximum residue limits established by the European Union (EU). The developed method provided high enrichment, by a factor of 35. The proposed method was utilized to determine the target insecticides in honey samples, and acceptable recoveries were obtained.

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