scholarly journals Size-dependent chemosensitization of doxorubicin-loaded polymeric nanoparticles for malignant glioma chemotherapy

Bioengineered ◽  
2021 ◽  
Author(s):  
Meng Gao ◽  
Yue Chen ◽  
Chenghu Wu
Keyword(s):  
Malignant Glioma ◽  
Polymeric Nanoparticles ◽  
Size Dependent

Size-dependent uptake of electrically neutral amphipathic polymeric nanoparticles by cell-sized liposomes and an insight into their internalization mechanism in living cells

2018 ◽  
Vol 54 (36) ◽  
pp. 4557-4560 ◽  
Author(s):  
S. Ichikawa ◽  
N. Shimokawa ◽  
M. Takagi ◽  
Y. Kitayama ◽  
T. Takeuchi
Keyword(s):  
Polymeric Nanoparticles ◽  
Living Cells ◽  
Size Dependent ◽  
Internalization Mechanism ◽  
Insight Into

The size-dependent uptake of amphipathic uncharged-nanoparticles in cell-sized liposomes is emerging as a new insight into their internalization mechanism in living cells.

Size-Dependent Radiosensitization Effects of Gold Nanoparticles on Human U251 Malignant Glioma Cells

2013 ◽  
Vol 5 (9) ◽  
pp. 990-994 ◽  
Author(s):  
Alexander Zaboronok ◽  
Hideo Tsurushima ◽  
Tetsuya Yamamoto ◽  
Tomonori Isobe ◽  
Kenta Takada ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Malignant Glioma ◽  
Glioma Cells ◽  
Size Dependent ◽  
Malignant Glioma Cells

scholarly journals Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

Pharmaceutics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 191 ◽  
Author(s):  
Vijay Mishra ◽  
Kuldeep Bansal ◽  
Asit Verma ◽  
Nishika Yadav ◽  
Sourav Thakur ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Solid Lipid Nanoparticles ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Lipid Nanoparticles ◽  
Delivery Systems ◽  
Routes Of Administration ◽  
Size Dependent ◽  
Solid Lipid ◽  
Nano Drug Delivery

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.

scholarly journals Size‐Dependent EPR Effect of Polymeric Nanoparticles on Tumor Targeting

2019 ◽  
Vol 9 (1) ◽  
pp. 1901223 ◽  
Author(s):  
Homan Kang ◽  
Sunghoon Rho ◽  
Wesley R. Stiles ◽  
Shuang Hu ◽  
Yoonji Baek ◽  
...  
Keyword(s):  
Tumor Targeting ◽  
Polymeric Nanoparticles ◽  
Epr Effect ◽  
Size Dependent

scholarly journals Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma

2014 ◽  
Vol 10 (1) ◽  
pp. 149-157 ◽  
Author(s):  
Giovanna M. Bernal ◽  
Michael J. LaRiviere ◽  
Nassir Mansour ◽  
Peter Pytel ◽  
Kirk E. Cahill ◽  
...  
Keyword(s):  
Malignant Glioma ◽  
In Vivo Imaging ◽  
Polymeric Nanoparticles ◽  
Convection Enhanced Delivery

Production and STEM examination of controlled-size silver clusters

1983 ◽  
Vol 41 ◽  
pp. 338-339
Author(s):  
M. A. Listvan ◽  
R. P. Andres
Keyword(s):  
Cluster Size ◽  
Metal Clusters ◽  
Experimental Parameter ◽  
Carbon Films ◽  
Metal Species ◽  
Silver Clusters ◽  
Free Jet ◽  
Size Dependent ◽  
Cluster Properties ◽  
Controllable Size

Knowledge of the function and structure of small metal clusters is one goal of research in catalysis. One important experimental parameter is cluster size. Ideally, one would like to produce metal clusters of regulated size in order to characterize size-dependent cluster properties.A source has been developed which is capable of producing microscopic metal clusters of controllable size (in the range 5-500 atoms) This source, the Multiple Expansion Cluster Source, with a Free Jet Deceleration Filter (MECS/FJDF) operates as follows. The bulk metal is heated in an oven to give controlled concentrations of monomer and dimer which were expanded sonically. These metal species were quenched and condensed in He and filtered to produce areosol particles of a controlled size as verified by mass spectrometer measurements. The clusters were caught on pre-mounted, clean carbon films. The grids were then transferred in air for microscopic examination. MECS/FJDF was used to produce two different sizes of silver clusters for this study: nominally Ag6 and Ag50.

Transfer Technique for Electron Microscopy of Membrance Filter Samples

1974 ◽  
Vol 32 ◽  
pp. 554-555
Author(s):  
Lawrence W. Ortiz ◽  
Bonnie L. Isom
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Pore Size ◽  
Membrane Filters ◽  
Size Dependent

A procedure is described for the quantitative transfer of fibers and particulates collected on membrane filters to electron microscope (EM) grids. Various Millipore MF filters (Millipore AA, HA, GS, and VM; 0.8, 0.45, 0.22 and 0.05 μm mean pore size) have been used with success. Observed particle losses have not been size dependent and have not exceeded 10%. With fibers (glass or asbestos) as the collected media this observed loss is approximately 3%.

Spindle scaling mechanisms

2020 ◽  
Vol 64 (2) ◽  
pp. 383-396
Author(s):  
Lara K. Krüger ◽  
Phong T. Tran
Keyword(s):  
Cell Size ◽  
Spindle Assembly ◽  
Dependent Manner ◽  
Post Translational Modification ◽  
Size Dependent ◽  
A Cell ◽  
Chromosome Separation ◽  
Spindle Elongation ◽  
Protein Gradients ◽  
Spindle Structure

Abstract The mitotic spindle robustly scales with cell size in a plethora of different organisms. During development and throughout evolution, the spindle adjusts to cell size in metazoans and yeast in order to ensure faithful chromosome separation. Spindle adjustment to cell size occurs by the scaling of spindle length, spindle shape and the velocity of spindle assembly and elongation. Different mechanisms, depending on spindle structure and organism, account for these scaling relationships. The limited availability of critical spindle components, protein gradients, sequestration of spindle components, or post-translational modification and differential expression levels have been implicated in the regulation of spindle length and the spindle assembly/elongation velocity in a cell size-dependent manner. In this review, we will discuss the phenomenon and mechanisms of spindle length, spindle shape and spindle elongation velocity scaling with cell size.

Miniaturised preparation of polymeric nanoparticles using droplet manipulation on open surfaces

2019 ◽  
Vol 14 (13) ◽  
pp. 1312-1316 ◽  
Author(s):  
Alsaeed M. Abualsayed ◽  
Sara A. Abouelmagd ◽  
Mohamed Abdelgawad
Keyword(s):  
Polymeric Nanoparticles ◽  
Droplet Manipulation
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