e14577 Background: Social media (SM) could transform how individuals learn of clinical trials. In an ongoing, single-center cohort study to collect serial biospecimens and clinical data from high-risk individuals (HRIs) for pancreatic cancer (PC), we explored how HRIs learned of the study, surveyed relevant SM posts and compared those referred by SM vs. other means. Methods: Initial recruitment focused on HRIs with familial risk for PC. Referral method was self-reported. We identified relevant SM posts and compared those referred via SM vs. other means by ANOVA and t-test. Investigators did not create SM content but were featured in a relevant local news clip, institutional blog post and Project Purple podcast; study-related media was IRB-approved. Results: We enrolled 91 HRIs between Aug 2018 and Jan 2019. Over half self-referred; 55.0% of self-referrals came from SM. We identified 16 unique SM posts, all to Facebook. Authors were 2 administrators for local hereditary cancer organizations, Project Purple, UNMC and 2 study subjects (9,4, 3 and 2 posts). Content included links to a podcast, clinicaltrials.gov, local news story, blog post, live chat and anecdotes from subjects. Nine posts shared study contact information or clinicaltrials.gov link. The mean age of those referred via SM was younger than for other methods (mean 49.2 vs. 53.4y) but was not statistically significant (p = 0.19). SM was more likely to recruit HRIs with familial risk than other methods (100.0% vs. 76.3%; p < 0.01) Conclusions: SM effectively recruited HRIs with familial risk for PC; this group may be more likely to seek information online. Individuals may find studies via SM without investigator involvement. SM may be an effective tool to recruit HRIs to early detection research in PC and other conditions. Clinical trial information: NCT03568630. [Table: see text]
Colaphellus palaestinus Achard, a new leaf-beetle for Europe (Coleoptera, Chrysomelidae, Chrysomelinae)
