Preventing Episode II: Relapse Prevention in First-Episode Psychosis

2005 ◽  
Vol 13 (4) ◽  
pp. 384-387 ◽  
Author(s):  
John Gleeson ◽  

Objective: This paper outlines a rationale for expanding research and clinical innovations focused upon relapse prevention following a first episode of psychosis. Some general principles for further progress are extracted from an overview of the first-episode psychosis (FEP) relapse literature. A cognitive behaviour therapy intervention for relapse prevention for FEP, that has been developed at the Early Psychosis Prevention and Intervention Centre, is described to illustrate these principles. Conclusions: Further progress is needed in refining interventions specific to the prevention of relapse following FEP. Future progress is dependent upon improved understanding of the interaction of biological, interpersonal and psychological processes underpinning relapse.

2011 ◽  
Vol 132 (2-3) ◽  
pp. 125-130 ◽  
Author(s):  
Kelly Allott ◽  
Mario Alvarez-Jimenez ◽  
Eoin J. Killackey ◽  
Sarah Bendall ◽  
Patrick D. McGorry ◽  
...  

2006 ◽  
Vol 34 (3) ◽  
pp. 277-291 ◽  
Author(s):  
Sarah Bendall ◽  
Henry J. Jackson ◽  
Eoin Killackey ◽  
Kelly Allott ◽  
Tracy Johnson ◽  
...  

There is increasing evidence that cognitive behavioural therapy (CBT) is efficacious in treating psychosis. However, very little attention has been paid to the nature of the control treatments used in studies of this. Befriending has been used as a control treatment in several randomized control trials (RCTs) of CBT for psychosis as it is simple to learn and administer. The aim of the present study was to examine whether Befriending controlled for important non-specific aspects of therapy when compared to CBT in a RCT for acute first episode psychosis (FEP). These non-specific factors included time in, expectancy created by, and acceptability of therapy. Expectations and enjoyment of therapy were measured by questionnaire. Time in therapy and the number of drop-outs were also recorded. Results showed that Befriending was comparable to CBT on measures of expectancy, enjoyment of therapy and drop-out rate, but significantly different with regard to time in therapy. This suggests that Befriending is a credible and acceptable control therapy for FEP with modification to increase time in therapy sessions. Methodological issues are raised, and suggestions for future research are made regarding control treatments.


2009 ◽  
Vol 70 (4) ◽  
pp. 477-486 ◽  
Author(s):  
John F. M. Gleeson ◽  
Sue M. Cotton ◽  
Mario Alvarez-Jimenez ◽  
Darryl Wade ◽  
Donna Gee ◽  
...  

1997 ◽  
Vol 25 (4) ◽  
pp. 371-379
Author(s):  
Ronald Siddle ◽  
Douglas Turkington ◽  
Robert E. J. Dudley

This single case study investigates a woman with organic hallucinosis, who was assessed using the Comprehensive Psychopathological Rating Scale (CPRS). She then received cognitive behaviour therapy (CBT) for 11 months. The CBT approach involved engaging the patient and specific symptom targeting. An individual formulation was developed, leading to schema focused intervention and relapse prevention. The subjects total CPRS scores and schizophrenia subscale scores were reduced dramatically.


2007 ◽  
Vol 37 (12) ◽  
pp. 1797-1806 ◽  
Author(s):  
VIOLA SPEK ◽  
IVAN NYKLÍČEK ◽  
NIELS SMITS ◽  
PIM CUIJPERS ◽  
HELEEN RIPER ◽  
...  

ABSTRACTBackgroundSubthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression. The current study had two aims: (1) to determine whether an internet-based cognitive behaviour therapy intervention and a group cognitive behaviour therapy intervention are more effective than a waiting-list control group; and (2) to determine whether the effect of the internet-based cognitive behaviour therapy differs from the group cognitive behaviour therapy intervention.MethodA total of 191 women and 110 men with subthreshold depression were randomized into internet-based treatment, group cognitive behaviour therapy (Lewinsohn's Coping With Depression course), or a waiting-list control condition. The main outcome measure was treatment response after 10 weeks, defined as the difference in pre- and post-treatment scores on the Beck Depression Inventory (BDI). Missing data, a major limitation of this study, were imputed using the Multiple Imputation (MI) procedure Data Augmentation.ResultsIn the waiting-list control group, we found a pre- to post-improvement effect size of 0·45, which was 0·65 in the group cognitive behaviour therapy condition and 1·00 within the internet-based treatment condition. Helmert contrasts showed a significant difference between the waiting-list condition and the two treatment conditions (p=0·04) and no significant difference between both treatment conditions (p=0·62).ConclusionsAn internet-based intervention may be at least as effective as a commonly used group cognitive behaviour therapy intervention for subthreshold depression in people over 50 years of age.


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