The Effect ofl‐Arginine onPorphyromonas gingivalis‐Induced Phagocytosis of a Murine Macrophage‐like Raw 264.7 Cell Line

2004 ◽  
Vol 26 (2) ◽  
pp. 309-313 ◽  
Author(s):  
Wihaskoro Sosroseno
Viruses ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 692
Author(s):  
Pui-San Wong ◽  
Richard Sutejo ◽  
Hui Chen ◽  
Sock-Hoon Ng ◽  
Richard Sugrue ◽  
...  

The poxviruses are large, linear, double-stranded DNA viruses about 130 to 230 kbp, that have an animal origin and evolved to infect a wide host range. Variola virus (VARV), the causative agent of smallpox, is a poxvirus that infects only humans, but other poxviruses such as monkey poxvirus and cowpox virus (CPXV) have crossed over from animals to infect humans. Therefore understanding the biology of poxviruses can devise antiviral strategies to prevent these human infections. In this study we used a system-based approach to examine the host responses to three orthopoxviruses, CPXV, vaccinia virus (VACV), and ectromelia virus (ECTV) in the murine macrophage RAW 264.7 cell line. Overall, we observed a significant down-regulation of gene expressions for pro-inflammatory cytokines, chemokines, and related receptors. There were also common and virus-specific changes in the immune-regulated gene expressions for each poxvirus-infected RAW cells. Collectively our results showed that the murine macrophage RAW 264.7 cell line is a suitable cell-based model system to study poxvirus host response.


PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0222044 ◽  
Author(s):  
Anna Poma ◽  
Giulia Vecchiotti ◽  
Sabrina Colafarina ◽  
Osvaldo Zarivi ◽  
Lorenzo Arrizza ◽  
...  

2005 ◽  
Vol 99 (3) ◽  
pp. 344-354 ◽  
Author(s):  
Roberta Pozzi ◽  
Barbara De Berardis ◽  
Luigi Paoletti ◽  
Cecilia Guastadisegni

2018 ◽  
Vol 94 (6) ◽  
pp. 607-618 ◽  
Author(s):  
Alberto López-Furelos ◽  
Aarón A. Salas-Sánchez ◽  
Francisco J. Ares-Pena ◽  
José M. Leiro-Vidal ◽  
Elena López-Martín

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