Import of fructose bisphosphate aldolase into the glycosomes of Trypanosoma brucei.
1987 ◽
Vol 105
(6)
◽
pp. 2649-2654
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Keyword(s):
The glycolytic enzymes of Trypanosomatids are compartmentalized within peroxisome-like microbodies called glycosomes. Fructose bisphosphate aldolase is synthesized on free polysomes and imported into glycosomes within 5 min. Peptide mapping reveals no primary structural differences between the in vivo-synthesized protein and that made in vitro from a synthetic template. However, native aldolase from glycosomes is partially protease resistant, whereas the in vitro translation product is not. Pulse-chase results indicate that aldolase in bloodstream trypanosomes has a much longer half-life than in the procyclic tsetse fly form.
2021 ◽
Keyword(s):
1987 ◽
Vol 66
(2)
◽
pp. 457-461
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1996 ◽
Vol 40
(11)
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pp. 2567-2572
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1986 ◽
Vol 6
(7)
◽
pp. 2663-2673
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Keyword(s):
1974 ◽
Vol 49
(2)
◽
pp. 215-222
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Keyword(s):
1977 ◽
Vol 43
(1)
◽
pp. 211-219
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Keyword(s):