scholarly journals Fragile phagocytes: FMRP positively regulates engulfment activity

2017 ◽  
Vol 216 (3) ◽  
pp. 531-533 ◽  
Author(s):  
Mary A. Logan
Keyword(s):  
Innate Immunity ◽  
Drosophila Melanogaster ◽  
Immune System ◽  
Immune Cells ◽  
Fragile X ◽  
Autism Spectrum ◽  
Abnormal Development ◽  
System Function ◽  
Immune System Function ◽  
Spectrum Disorders

Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O’Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

EFFECT OF PETTING A DOG ON IMMUNE SYSTEM FUNCTION

2004 ◽  
Vol 95 (7) ◽  
pp. 1087 ◽  
Author(s):  
CARL J. CHARNETSKI
Keyword(s):  
Immune System ◽  
System Function ◽  
Immune System Function

scholarly journals Effects of Long-Term Supplementation of Bovine Colostrum on the Immune System in Young Female Basketball Players. Randomized Trial

Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 118
Author(s):  
Anna Skarpańska-Stejnborn ◽  
Mirosława Cieślicka ◽  
Hanna Dziewiecka ◽  
Sławomir Kujawski ◽  
Anita Marcinkiewicz ◽  
...  
Keyword(s):  
Immune System ◽  
Physical Exercise ◽  
Exercise Program ◽  
Bovine Colostrum ◽  
Control Group ◽  
System Function ◽  
Basketball Players ◽  
Immune System Function ◽  
Experimental Group

An intensive physical exercise program could lead to a decrease in immune system function. Effects of long-term supplementation of bovine colostrum on the response of immune function on physical exercise test in athletes were examined. Twenty-seven elite female basketball players (age 16–19) were randomly assigned to either an experimental group or a control group. Eventually, n = 11 athletes completed intervention in the experimental group (3.2 g bovine colostrum orally twice a day for 24 weeks), while n = 9 athletes in the control group were given a placebo. Before the supplementation, after 3 and 6 months, subjects performed the physical exercise stress test. Before, just after, and 3 h after physical exercise testing, blood was drawn and immune system indicators were examined. Plasma interleukin (IL)-1alpha, IL-2, IL-10, IL-13, tumor necrosis factor (TNF) alpha, creatine kinase (CK MM), immunoglobulin G (IgG), insulin-like growth factor 1 (IGF1), and WBC, lymphocyte (LYM), monocyte (MON), and granulocyte (GRA) were measured. A statistically significant change in IL-10 in response to the exercise program during the supplementation period in both groups was observed (p = 0.01). However, the results of the rest of the comparisons were statistically insignificant (p > 0.05). Contrary to our initial hypothesis, there were no significant effects of bovine supplementation on the dynamics of immune system function indicators.

Physical exercise and immune system function in cancer survivors

Cancer ◽  
2002 ◽  
Vol 94 (2) ◽  
pp. 539-551 ◽  
Author(s):  
Adrian S. Fairey ◽  
Kerry S. Courneya ◽  
Catherine J. Field ◽  
John R. Mackey
Keyword(s):  
Immune System ◽  
Physical Exercise ◽  
Cancer Survivors ◽  
System Function ◽  
Immune System Function

scholarly journals In utero cell transfer between porcine littermates

2011 ◽  
Vol 23 (2) ◽  
pp. 297 ◽  
Author(s):  
Andrea McConico ◽  
Kim Butters ◽  
Karen Lien ◽  
Bruce Knudsen ◽  
Xiaosheng Wu ◽  
...  
Keyword(s):  
Immune System ◽  
Cord Blood ◽  
Normal Pregnancy ◽  
Human Cells ◽  
Cell Transfer ◽  
System Function ◽  
Human Cord Blood ◽  
Immune System Function ◽  
Vascular Connections

Trafficking of cells between mother and fetus during the course of normal pregnancy is well documented. Similarly, cells are known to travel between twins that share either a placenta (i.e. monozygotic) or associated chorion (i.e. monochorionic). Transferred cells are thought to be channelled via the vessels of the placenta or vascular connections established via the chorion and the long-term presence of these cells (i.e. microchimerism) can have important consequences for immune system function and reparative capacity of the host. Whether cells can be transferred between twins with separate placentas and separate chorions (i.e. no vascular connections between placentas) has not been investigated nor have the biological consequences of such a transfer. In the present study, we tested the possibility of this type of cell transfer by injecting human cord blood-derived cells into a portion of the littermates of swine and probing for human cells in the blood and tissues of unmanipulated littermates. Human cells were detected in the blood of 78% of unmanipulated littermates. Human cells were also detected in various tissues of the unmanipulated littermates, including kidney (56%), spleen (33%), thymus (11%) and heart (22%). Human cells were maintained in the blood until the piglets were sacrificed (8 months after birth), suggesting the establishment of long-term microchimerism. Our findings show that the transfer of cells between fetuses with separate placentas and separate chorions is significant and thus such twins may be subject to the same consequences of microchimerism as monozygotic or monochorionic counterparts.

scholarly journals T-bet-Deficient NOD Mice Are Protected from Diabetes Due to Defects in Both T Cell and Innate Immune System Function

2009 ◽  
Vol 183 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Jonathan H. Esensten ◽  
Michael R. Lee ◽  
Laurie H. Glimcher ◽  
Jeffrey A. Bluestone
Keyword(s):  
Immune System ◽  
T Cell ◽  
Innate Immune System ◽  
Nod Mice ◽  
Innate Immune ◽  
System Function ◽  
Immune System Function

scholarly journals The Effect of Air Pollution on the Immune System

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Diana Liu
Keyword(s):  
Cardiovascular Disease ◽  
Air Pollution ◽  
Innate Immunity ◽  
Particulate Matter ◽  
Immune System ◽  
Sulfur Dioxide ◽  
Nitrogen Oxide ◽  
Immune Cells ◽  
Cytokine Secretion ◽  
Acquired Immunity

Air pollution has become a serious problem, the pollutant mainly came from industrial and vehicle exhaustion will harm people’s bodies to a different extent, cause lots of diseases like asthma, and cardiovascular disease. The system protects us are also be damaged by pollutant entering the tissue barrier, harm to immune cells and regulate cytokine secretion. This essay is mainly focused on the particulate matter, sulfur dioxide, and nitrogen oxide effect on the immune system from the innate immunity to the acquired immunity, and how the immune system defense.

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