scholarly journals Effects of Long-Term Supplementation of Bovine Colostrum on the Immune System in Young Female Basketball Players. Randomized Trial

Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 118
Author(s):  
Anna Skarpańska-Stejnborn ◽  
Mirosława Cieślicka ◽  
Hanna Dziewiecka ◽  
Sławomir Kujawski ◽  
Anita Marcinkiewicz ◽  
...  

An intensive physical exercise program could lead to a decrease in immune system function. Effects of long-term supplementation of bovine colostrum on the response of immune function on physical exercise test in athletes were examined. Twenty-seven elite female basketball players (age 16–19) were randomly assigned to either an experimental group or a control group. Eventually, n = 11 athletes completed intervention in the experimental group (3.2 g bovine colostrum orally twice a day for 24 weeks), while n = 9 athletes in the control group were given a placebo. Before the supplementation, after 3 and 6 months, subjects performed the physical exercise stress test. Before, just after, and 3 h after physical exercise testing, blood was drawn and immune system indicators were examined. Plasma interleukin (IL)-1alpha, IL-2, IL-10, IL-13, tumor necrosis factor (TNF) alpha, creatine kinase (CK MM), immunoglobulin G (IgG), insulin-like growth factor 1 (IGF1), and WBC, lymphocyte (LYM), monocyte (MON), and granulocyte (GRA) were measured. A statistically significant change in IL-10 in response to the exercise program during the supplementation period in both groups was observed (p = 0.01). However, the results of the rest of the comparisons were statistically insignificant (p > 0.05). Contrary to our initial hypothesis, there were no significant effects of bovine supplementation on the dynamics of immune system function indicators.

Cancer ◽  
2002 ◽  
Vol 94 (2) ◽  
pp. 539-551 ◽  
Author(s):  
Adrian S. Fairey ◽  
Kerry S. Courneya ◽  
Catherine J. Field ◽  
John R. Mackey

2011 ◽  
Vol 23 (2) ◽  
pp. 297 ◽  
Author(s):  
Andrea McConico ◽  
Kim Butters ◽  
Karen Lien ◽  
Bruce Knudsen ◽  
Xiaosheng Wu ◽  
...  

Trafficking of cells between mother and fetus during the course of normal pregnancy is well documented. Similarly, cells are known to travel between twins that share either a placenta (i.e. monozygotic) or associated chorion (i.e. monochorionic). Transferred cells are thought to be channelled via the vessels of the placenta or vascular connections established via the chorion and the long-term presence of these cells (i.e. microchimerism) can have important consequences for immune system function and reparative capacity of the host. Whether cells can be transferred between twins with separate placentas and separate chorions (i.e. no vascular connections between placentas) has not been investigated nor have the biological consequences of such a transfer. In the present study, we tested the possibility of this type of cell transfer by injecting human cord blood-derived cells into a portion of the littermates of swine and probing for human cells in the blood and tissues of unmanipulated littermates. Human cells were detected in the blood of 78% of unmanipulated littermates. Human cells were also detected in various tissues of the unmanipulated littermates, including kidney (56%), spleen (33%), thymus (11%) and heart (22%). Human cells were maintained in the blood until the piglets were sacrificed (8 months after birth), suggesting the establishment of long-term microchimerism. Our findings show that the transfer of cells between fetuses with separate placentas and separate chorions is significant and thus such twins may be subject to the same consequences of microchimerism as monozygotic or monochorionic counterparts.


2015 ◽  
Vol 5 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Hanna Karen M. Antunes ◽  
Marco Túlio De Mello ◽  
Valdir de Aquino Lemos ◽  
Ruth Ferreira Santos-Galduróz ◽  
Luciano Camargo Galdieri ◽  
...  

Background: Physical exercise influences homocysteine (Hcy) concentrations, cognitive function and the metabolic profile. The purpose of this study was to investigate the influence of regular physical exercise on Hcy levels, the metabolic profile and cognitive function in healthy elderly males before and after an endurance exercise program. Methods: Forty-five healthy and sedentary volunteers were randomized into 2 groups: (1) a control group asked not to change their normal everyday activities and not to start any regular physical exercise program and (2) an experimental group trained at a heart rate intensity corresponding to ventilatory threshold 1 (VT-1) for 60 min/day 3 times weekly on alternate days for 6 months using a cycle ergometer. All volunteers underwent cognitive evaluations, blood sample analyses and ergospirometric assessments. Results: A significant improvement in cognitive function was observed in the experimental group compared with the control group (p < 0.05). No significant changes in Hcy levels were observed in the experimental group (p > 0.05), but there was a significant increase in peak oxygen consumption and workload at VT-1 as well as a significant improvement in cholesterol, triglycerides, HDL, glucose, alkaline phosphatase, urea, T3, T4 and prostate-specific antigen compared with the control group (p < 0.05). Conclusion: The data suggest that a physical exercise program does not reduce Hcy levels in healthy elderly males, although it improves the cardiovascular and metabolic profile as well as cognitive function.


Kinesiology ◽  
2017 ◽  
Vol 49 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Miguel-Ángel Gómez ◽  
Jaime Sampaio

This study identified the short- and long-term effects of using a shooting strap on the accuracy of freethrows performed by U15 female basketball players during training and competition. Thirty six female<br>basketball player volunteers (aged 14.3±0.5 years) from the Lithuanian Schoolchildren Basketball League were randomly assigned to either an experimental or control group. The experimental group used a shooting strap that immobilized movements of the supporting hand while shooting. The control group performed freethrows without any training aid. Learning and transfer of performance was assessed before and after the intervention training sessions (4-week intervention program applied 4 times per week), and on a retention test after one year. Results showed that: (a) free-throw accuracy was higher after one month and after one year of intervention than before the intervention training program in both practice and competition; (b) the experimental group scored better in practice and competition than the control group after one month and one year of the intervention; and (c) free-throw accuracy was higher during training sessions than during&nbsp;competition. The identified short-term and long-term improvements in free-throw shooting accuracy support the usage of shooting straps. The use of shooting straps and external assisting devices might allow adjusting programs of training to provide fluent free-throw accuracy progresses from youth to senior categories.


2020 ◽  
Vol 10 (23) ◽  
pp. 8391
Author(s):  
María Victoria Palop-Montoro ◽  
Emilio Lozano-Aguilera ◽  
Milagros Arteaga-Checa ◽  
Víctor Serrano-Huete ◽  
Juan Antonio Párraga-Montilla ◽  
...  

Background: Sleep is an important phenomenon to restore the body, both physically and emotionally, providing a state of balance in the person. It has been proven that adequate sleep at night is one of the main needs of older people in order to maintain an active and healthy life; among other factors, regular physical exercise can improve the quality of sleep. The aim of this research is to evaluate the effects of a physical exercise program supplemented with vibration training on sleep quality and the use of sleep drugs in women over 65 years of age. Methods: Fifty-two independent, physically active adult women were randomised into two groups: a physical exercise program (n = 26, control group) and the same physical exercise program supplemented with vibration training (n = 26, experimental group). The control group performed two weekly sessions of exercise, and the experimental group added another two sessions of vibration training to these two sessions for 12 weeks. Sleep quality was assessed using the Pittsburgh index. Statistical significance was established as p < 0.05. Results: After the intervention, there were significant changes to the quality of sleep (p = 0.001) and hours of sleep (p = 0.002) in the experimental group. The consumption of drugs decreased in this group, although not significantly; however, it did have a moderate effect size (p = 0.058; d = 0.36). The control group, on the other hand, reported significantly worsened sleep quality (p = 0.001) and increased drug use (p = 0.008). Conclusion: Three months of vibration training, as a complement to a conventional physical exercise program, improves sleep quality and reduces the consumption of sleeping pills in women over 65 years of age.


2021 ◽  
Vol 73 (10) ◽  
pp. 695-701
Author(s):  
Jittima Panyasarawut ◽  
Wallada Chanruangvanich ◽  
Prangtip Chayaput ◽  
Theerapol Witthiwej

Objective: This research aimed to study the effects of a physical exercise program on physical mobility in cranial surgery patients.Materials and Methods: The researcher used a quasi-experimental method of surveying 58 patients who had cranial surgery at Siriraj Hospital. The research group was divided into two groups: an experimental group (28 patients) participating in a physical exercise program of patients after cranial surgery, and a control group (30 patients) receiving routine nursing care only. The evaluation of the patients’ physical mobility was performed three days after the surgery.Results: Most patients in the research group had an intracranial tumor (86.2%). One day after the surgery, the experimental group had minor pain at the wound site while the control group had moderate pain. Both groups felt discomfort (64.2%) or had muscle stiffness in the neck and shoulder areas (63.3%). Three days after the surgery, at the end of the program, the body movement function of both groups was reduced compared with the preoperative data. However, the experimental group showed better body movement function scores than the control one as the scores of the former were reduced less than those of the latter at p < 0.05.Conclusion: Nurses who provide health care services to patients after cranial surgery should apply the physical exercise program to promote the recovery of the patients’ physical mobility.


2019 ◽  
Vol 25 (6) ◽  
pp. 515-519
Author(s):  
Rafael Cunha Laux ◽  
Sara Teresinha Corazza

ABSTRACT Introduction Work activities have been occupying an increasing amount of time in the daily lives of the population, making individuals less physically active. A job market strategy is to invest in physical exercise programs in the actual workplace to improve the physical and cognitive aspects of these employees. Objective To verify the effects of a workplace physical exercise program on the simple and choice reaction times of public university employees. Methods Twenty-six physically inactive male and female subjects with a mean age of 29.62 ± 6.47 years underwent a program consisting of thirty-six sessions with physical exercises in the workplace, held three times a week over twelve weeks. Simple reaction time (SRT) and choice reaction time (CRT) were assessed before and after the intervention, using the Vienna Test System®, and the results were presented in: I) reaction time, II) movement time; and (III) response time. Descriptive and inferential statistical analyses were conducted using the statistical program SPSS® (version 21.0 for Windows), with a significance level of 5%. Results When observing the SRT and CRT variables before and after the experiment, we noticed an improvement in reaction time, movement time and response time in the experimental group but not in the control group. Conclusion The workplace physical exercise program was able to reduce the SRT and CRT of the experimental group. Level of evidence I; randomized clinical trial.


2021 ◽  
Vol 67 (4) ◽  
pp. 482-489
Author(s):  
Romana Romanov ◽  
Ladislav Mesarič ◽  
Dušan Perić ◽  
Jasna Vešligaj Damiš ◽  
Yoana Petrova Filišič

Objectives: This study aims to investigate the effects of adapted physical exercise on the level of muscular ability and attention process in patients with traumatic brain injury (TBI). Patients and methods: Between September 2018 and November 2018, a total of 25 male patients with TBI (mean age: 41.1±9.7 years; range, 30 to 50 years) that occurred two years ago were included in this randomized-controlled study. The patients were divided into two groups as the experimental group (n=13) and the control group (n=12). The experimental group implemented a regular rehabilitation program and an additional program of adapted physical exercise. The control group implemented only a regular rehabilitation program (morning gymnastics and gymnastics for the brain). Motor and functional abilities were assessed by a Senior Fitness battery and Berg's balance scale. Attention process was assessed by a standardized d2 test. Results: A significant improvement in physical abilities (strength, flexibility and balance) and attention process was observed in both groups (p<0.01). The improvement was greater in the experimental group (p<0.01). Conclusion: Traumatic brain injury causes difficulties in the memory and executive functions of the body and impairs working ability. The short-term adapted physical exercise program can yield a positive change in working abilities of patients with TBI.


2020 ◽  
Author(s):  
Ann Van de Winckel ◽  
Tanjila Nawshin ◽  
Casey Byron

BACKGROUND Patients with chronic diseases often must adhere to a long-term individualized home exercise program (HEP) to manage their symptoms, and improve or maintain their cardiovascular health, flexibility and/or strength. Those exercises are provided and updated during physical therapy (PT) visits. Limited adherence (ie, perform the required number of HEP/week) to long-term exercise reduces the capacity of exercise to improve or stabilize impairments related to chronic disease. Lower socio-economic status is an additional factor that negatively impacts exercise adherence. To mitigate this, online apps available to motivate people to exercise could be a viable option. Using an app through telehealth may benefit adults with chronic diseases achieve long-term home exercise program (HEP) adherence. However, because using apps for rehabilitation is an emerging field, the app’s feasibility needs to be evaluated. OBJECTIVE To address HEP adherence in participants with chronic diseases and in financial distress, defined by people being on Medicaid or similar programs, we evaluated HEP adherence, compliance (ie, percentage of participant-recorded videos sent), as well as satisfaction with the PT care and with the Hudl Technique® app and telehealth in terms of feasibility, compared to standard HEP on paper. METHODS We recruited patients scheduled for outpatient PT. We performed a randomized controlled trial where the experimental group received weekly HEP demonstrations through app videos on a tablet and received feedback on their self-recorded HEP video performance from the telehealth-physical therapist. The control group received HEP on paper without feedback as is custom in PT practice. The treating therapist and data analyst were blinded to the allocation. Demographic, clinical, and health coverage information was collected for screening and baseline measurements. Adherence and compliance were evaluated. Both groups completed surveys at 8 and 24 weeks on satisfaction with PT care and, for the experimental group, also satisfaction with the app/telehealth use. RESULTS Forty-five adults with chronic diseases and financial distress were randomized into an experimental (n=23) and a control group (n=22), with respectively 17 and 19 participants completing the 24-week HEP. The experimental group maintained a HEP adherence frequency of 4±2 times/week at 8 and 24 weeks (P=.29), whereas in the control group HEP adherence decreased from 4±2 to 3±2 times/week (P=.07), with a significant difference (P=.04) between groups at 24 weeks. Sixty-eight percent of participants sent videos. They sent on average 68% of the requested number of videos. The average score for satisfaction with PT care was maintained at 87% in the experimental group (P=1.00) whereas it dropped from 89% at 8 weeks to 74% at 24 weeks (P=.008) in the control group. There were no app-related adverse events. CONCLUSIONS The Hudl app/telehealth is feasible for delivering HEP and helps participants with chronic diseases and financial distress maintain HEP adherence. CLINICALTRIAL The full trial protocol is available at ClinicalTrials.gov (NCT02659280).


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