Bloodborne Viral Infections in Patients Attending an Emergency Room in Mexico City: Estimate of Seroconversion Probability in Healthcare Workers After an Occupational Exposure

2000 ◽  
Vol 21 (9) ◽  
pp. 600-602 ◽  
Author(s):  
Midori Kato-Maeda ◽  
Samuel Ponce-de-León ◽  
Jose Sifuentes-Osornio ◽  
M. Sigfrido Rangel-Frausto ◽  
Juan Calva-Mercado ◽  
...  

AbstractThe frequency of hepatitis C (HCV), hepatitis B (HBV), human immunodeficiency virus (HIV), and human T-cell lymphotropic virus (HTLV) I/II was determined in the emergency room of a teaching hospital. Of 909 patients, 19% had at least one infection; 7.8% had HCV, 6.9% HBV, 3.3% HIV, and 2.8% HTLV I/II. The probability that a healthcare worker would have an accident with an infected patient and seroconvert was 4.99 to 24.9 per 100,000 venipunctures for HBV, 5.6 to 8.4 for HCV, and 0.12-0.16 for HIV in our emergency room.


Biology ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 192 ◽  
Author(s):  
Paulina Glowacka ◽  
Lidia Rudnicka ◽  
Olga Warszawik-Hendzel ◽  
Mariusz Sikora ◽  
Mohamad Goldust ◽  
...  

This review updates current knowledge regarding the risk of viral infections, including COVID-19, in patients treated with cyclosporine. We also shortly refer to bacterial infections and parasitic infestations in patients treated with cyclosporin. Cyclosporine is an immunosuppressive drug, which is widely used in medicine, including in the treatment of autoimmune skin diseases in dermatology, rheumatology, ophthalmology and nephrology, and in organ transplantation. A usual concern associated with immunosuppressive treatment is the potential risk of infections. Interestingly, several data indicate a relatively low risk of infections, especially viral infections, in patients receiving cyclosporine. It was shown that cyclosporine exerts an inhibitory effect on the replication of some viruses, or may have a potentially beneficial effect on the disease course in infections. These include hepatitis C, influenza virus, rotavirus, human immunodeficiency virus and coronavirus infections. Available data indicate that cyclosporine may have a beneficial effect on COVID-19, which is caused by the coronavirus SARS-COV2.





2017 ◽  
Vol 4 (3) ◽  
pp. 896
Author(s):  
Ashish Pradhan ◽  
Dheeraj Khatri ◽  
Luna Adhikari

Background: There is a high prevalence of HIV infection in adolescents of India, especially the north eastern states but awareness on blood borne viral infections among them is poor.Methods: Four hundred and ninety students aged thirteen to nineteen from seven schools and seven colleges of East Sikkim were interviewed on behavior related to transmission of blood borne viral infections and their blood was tested for Hepatitis B surface antigen, anti-Human Immunodeficiency virus and Hepatitis C virus antibodies.Results: None of the students tested positive for anti-Human Immunodeficiency virus and Hepatitis C virus antibodies and only one tested positive for Hepatitis B surface antigen. 6.7% of students gave history of heterosexual relationship.Conclusions: Despite the presence of behaviors associated with risk of acquiring blood borne viral infections in our adolescents we found a low prevalence of these infections, hence there is a need to do similar studies involving more and different cohort of adolescents.





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