scholarly journals Lack of Clinical Significance for the Common Arginine‐to‐Leucine Substitution at Codon 463 of the katG Gene in Isoniazid‐Resistant Mycobacterium tuberculosis in Singapore

1997 ◽  
Vol 176 (4) ◽  
pp. 1126-1127 ◽  
Author(s):  
James M. Musser
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Clinical Significance ◽  
Katg Gene ◽  
The Common

scholarly journals Lack of Clinical Significance for the Common Arginine‐to‐Leucine Substitution at Codon 463 of the katG Gene in Isoniazid‐Resistant Mycobacterium tuberculosis in Singapore

1997 ◽  
Vol 176 (4) ◽  
pp. 1125-1126 ◽  
Author(s):  
Ann Siew‐Gek Lee ◽  
Lynn Lay‐Hoon Tang ◽  
Irene Hua‐Khim Lim ◽  
Moi‐Lin Ling ◽  
Leng Tay ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Clinical Significance ◽  
Katg Gene ◽  
The Common

scholarly journals Vitamin C and the common cold

1992 ◽  
Vol 67 (1) ◽  
pp. 3-16 ◽  
Author(s):  
Harri Hemilä
Keyword(s):  
Vitamin C ◽  
Clinical Significance ◽  
Common Cold ◽  
Antioxidant Property ◽  
Considerable Decrease ◽  
Infected People ◽  
Supplemental Vitamin ◽  
The Subject ◽  
The Common

The effect of vitamin C on the common cold has been the subject of several studies. These studies do not support a considerable decrease in the incidence of the common cold with supplemental vitamin C. However, vitamin C has consistently decreased the duration of cold episodes and the severity of symptoms. The benefits that have been observed in different studies show a large variation and, therefore, the clinical significance may not be clearly inferred from them. The biochemical explanation for the benefits may be based on the antioxidant property of vitamin C. In an infection, phagocytic leucocytes become activated and they produce oxidizing compounds which are released from the cell. By reacting with these oxidants, vitamin C may decrease the inflammatory effects caused by them. Scurvy, which is caused by a deficiency in vitamin C, is mostly attributed to the decreased synthesis of collagen. However, vitamin C also participates in several other reactions, such as the destruction of oxidizing substances. The common cold studies indicate that the amounts of vitamin C which safely protect from scurvy may still be too low to provide an efficient rate for other reactions, possibly antioxidant in nature, in infected people.

Anatomic relationship between the common femoral artery and vein: CT evaluation and clinical significance.

Radiology ◽  
1989 ◽  
Vol 173 (3) ◽  
pp. 775-777 ◽  
Author(s):  
P A Baum ◽  
A H Matsumoto ◽  
G P Teitelbaum ◽  
R A Zuurbier ◽  
K H Barth
Keyword(s):  
Clinical Significance ◽  
Femoral Artery ◽  
Common Femoral Artery ◽  
Ct Evaluation ◽  
The Common ◽  
Anatomic Relationship

scholarly journals Pulmonary Azygous Lobe-An Anatomical Variant

2015 ◽  
Vol 12 (2) ◽  
pp. 151-152 ◽  
Author(s):  
W Seiber ◽  
N Karcara ◽  
P Pant
Keyword(s):  
Medical Journal ◽  
Clinical Significance ◽  
Anatomical Variant ◽  
X Ray ◽  
Accessory Lobe ◽  
Anatomical Basis ◽  
Deep Groove ◽  
Chest X Ray ◽  
The Common ◽  
The Right

Pulmonary azygous lobe is one of the common lung malformations. There is only few article about azygous lobe. Its a small accessory lobe sometimes found on the upper part of the right lung, separated from the rest of the upper lobe by a deep groove lodging the ayzygous vein. This reports describes the presence of azygous lobe, a rare anatomical variant, encountered during chest x-ray discussion. We describe here the anatomical basis and the clinical significance of azygous lobe.Kathmandu University Medical Journal Vol.12(2) 2014: 151-152

scholarly journals Direct detection of rpoB and katG gene mutations of Mycobacterium tuberculosis in clinical samples

2017 ◽  
Vol 7 (8) ◽  
pp. 698-701
Author(s):  
Sunil Pandey ◽  
Ashima Lamichhane ◽  
Anu Byanjankar ◽  
Ansuma Kharel ◽  
Chandrakala Rai ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Direct Detection ◽  
Gene Mutations ◽  
Clinical Samples ◽  
Katg Gene

scholarly journals Vascular Supply to the Liver: A Report of a Rare Arterial Variant

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Peter B. Johnson ◽  
Shamir O. Cawich ◽  
Sundeep Shah ◽  
Michael T. Gardner ◽  
Patrick Roberts ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Clinical Significance ◽  
Rare Variant ◽  
Vascular Supply ◽  
Common Hepatic Artery ◽  
Arterial Supply ◽  
Variant Pattern ◽  
Classic Pattern ◽  
Coeliac Trunk ◽  
The Common

In the classic description of hepatic arterial supply, the common hepatic artery originates from the coeliac trunk. However, there are numerous variations to this classic pattern. We report a rare variant pattern of hepatic arterial supply and discuss the clinical significance of this variation.

scholarly journals Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus)

2013 ◽  
Vol 81 (8) ◽  
pp. 2909-2919 ◽  
Author(s):  
Laura E. Via ◽  
Danielle M. Weiner ◽  
Daniel Schimel ◽  
Philana Ling Lin ◽  
Emmanuel Dayao ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Human Disease ◽  
Small Animal ◽  
Common Marmoset ◽  
Callithrix Jacchus ◽  
Primate Model ◽  
Content Type ◽  
Positron Emission ◽  
The Common ◽  
Fdg Pet Ct

ABSTRACTExisting small-animal models of tuberculosis (TB) rarely develop cavitary disease, limiting their value for assessing the biology and dynamics of this highly important feature of human disease. To develop a smaller primate model with pathology similar to that seen in humans, we experimentally infected the common marmoset (Callithrix jacchus) with diverse strains ofMycobacterium tuberculosisof various pathogenic potentials. These included recent isolates of the modern Beijing lineage, the Euro-American X lineage, andM. africanum. All three strains produced fulminant disease in this animal with a spectrum of progression rates and clinical sequelae that could be monitored in real time using 2-deoxy-2-[18F]fluoro-d-glucose (FDG) positron emission tomography (PET)/computed tomography (CT). Lesion pathology at sacrifice revealed the entire spectrum of lesions observed in human TB patients. The three strains produced different rates of progression to disease, various extents of extrapulmonary dissemination, and various degrees of cavitation. The majority of live births in this species are twins, and comparison of results from siblings with different infecting strains allowed us to establish that the infection was highly reproducible and that the differential virulence of strains was not simply host variation. Quantitative assessment of disease burden by FDG-PET/CT provided an accurate reflection of the pathology findings at necropsy. These results suggest that the marmoset offers an attractive small-animal model of human disease that recapitulates both the complex pathology and spectrum of disease observed in humans infected with variousM. tuberculosisstrain clades.

scholarly journals Hasil diagnostik Mycobacterium tuberculosis pada penderita batuk ≥2 minggu dengan pewarnaan Ziehl-Neelsen di Puskesmas Ranomuut dan Puskesmas Kombos Manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Ramalia P. Mohamad ◽  
John Porotu'o ◽  
Heriyannis Homenta
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Positive Result ◽  
Staining Method ◽  
Descriptive Study ◽  
Health Centers ◽  
Common Symptom ◽  
Acid Fast Bacilli ◽  
Primary Health ◽  
The Common

Abstract: The common symptom of lung disease is cough which is usually recovered after 2-3 weeks. However, if the cough persists continually then it should be paid attention seriously ith detect Mycobacterium tuberculosis in the sputum of patients with cough ≥2 weeks at Puskesmas Ranomuut and Puskesmas Kombos (primary health centers) in Manado by using the Ziehl-Neelsen staining method. This was a descriptive study using total sampling from August to November 2016. The results showed that there were 25 patients with cough ≥2 weeks; 7 patients at Puskesmas Ranomuut and 18 patients at Puskesmas Kombos. The majority of patients were male (68%) and aged 15-34 years old (44%). The Ziehl-Neelsen staining of patients’ sputum revealed that at Puskesmas Kombos there were 2 patients (11,1%) with positive acid-fast bacilli meanwhile at Puskesmas Ranomuut there was no positive result. Conclusion: Acid-fast bacilli were detected in 11.1% patients with cough ≥2 weeks at Puskesmas Kombos only. Keywords: Mycobacterium tuberculosis, pulmonary tuberculosis, Ziehl-Neelsen Abstrak: Gejala penyakit paru yang paling sering ditemukan ialah batuk. Batuk biasanya akan membaik dalam 2-3 minggu namun bila batuk terjadi terus-menerus perlu diselidiki lebih lanjut karena merupakan gejala utama dari penyakit tuberkulosis paru. Penelitian ini bertujuan untuk mendeteksi adanya kuman Mycobacterium tuberkulosis dalam dahak penderita batuk ≥2 minggu di Puskesmas Ranomuut dan Puskesmas Kombos dengan pemeriksaan mikrobiologi menggunakan teknik pewarnaan Ziehl-Neelsen. Jenis penelitian ialah deskriptif. Pengambilan sampel menggunakan cara total sampling dalam kurun waktu Agustus-November 2016. Hasil penelitian mendapatkan 25 pasien batuk ≥2 minggu terdiri dari 7 pasien di Puskesmas Ranomuut dan 18 pasien di Puskesmas Kombos. Jumlah pasien laki-laki (68%) lebih banyak dibandingkan perempuan (32%) dengan usia terbanyak 15-34 tahun (44%). Pada pemeriksaan BTA di Puskesmas Ranomuut tidak ditemukan pasien dengan BTA positif sedangkan di Puskesmas Kombos terdapat 2 pasien dengan BTA positif (11,1%). Simpulan: Kuman BTA positif dalam sputum penderita batuk ≥2 minggu sebanyak 2 orang (11,1%) hanya di Puskesmas Kombos.Kata kunci: Mycobacterium tuberculosis, tuberkulosis paru, Ziehl-Neelsen

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