Estimation of regional hemoglobin concentration in biological tissues using diffuse reflectance spectroscopy with a novel spectral interpretation algorithm

2011 ◽  
Vol 56 (13) ◽  
pp. 3985-4000 ◽  
Author(s):  
P Chen ◽  
B Fernald ◽  
W Lin
Keyword(s):  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Hemoglobin Concentration ◽  
Biological Tissues ◽  
Reflectance Spectroscopy ◽  
Spectral Interpretation ◽  
Interpretation Algorithm

Medical applications of reflectance spectroscopy in the diffusive and sub-diffusive regimes

2018 ◽  
Vol 26 (6) ◽  
pp. 337-350 ◽  
Author(s):  
Sharmin Akter ◽  
Md. Golzar Hossain ◽  
Izumi Nishidate ◽  
Hisanao Hazama ◽  
Kunio Awazu
Keyword(s):  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Biological Tissues ◽  
Disease Diagnosis ◽  
Structural Features ◽  
Reflectance Spectroscopy ◽  
Medical Applications ◽  
Light Spectrum ◽  
Tissue Morphology ◽  
Reflected Light

Diffuse reflectance spectroscopy is a widely used technique for medical applications that may analyze the optical characteristics of biological tissues. By using diffuse reflectance spectroscopy, different tissue types can be distinguished based on specific changes on reflected light spectrum that are a result of differences on a molecular level between compared tissues. Identification of the structural features of tissue can be performed by applying diffuse reflectance spectroscopy, and the spectra obtained from this technique could provide important diagnostic information about the tissue morphology and physiology. Moreover, different tissue types can be classified using diffuse reflectance spectroscopy, during surgery on the basis of their optical properties that are related to the tissue morphology and constituents. In recent years, several research groups have been shown the feasibility of diffuse reflectance spectroscopy in discriminating benign and malignant tissue, and thus making it a good competitor for margin assessment. Therefore, the diffuse reflectance spectroscopy has the possibility to become an important optical means for disease diagnosis, treatment and prognosis monitoring. This review represents a summary of the literature on diffuse reflectance spectroscopy and its important clinical applications.

scholarly journals Diffuse Reflectance Spectroscopy reveals heat stress-induced changes in hemoglobin profile in chicken breast

2019 ◽  
Author(s):  
Sina Dadgar ◽  
Liz Greene ◽  
Ahmed Dhamad ◽  
Barbara Mallmann ◽  
Sami Dridi ◽  
...  
Keyword(s):  
Heat Stress ◽  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Hemoglobin Concentration ◽  
Reflectance Spectroscopy ◽  
Optical Data ◽  
Chicken Breast ◽  
Poultry Industry ◽  
Short Period ◽  
Induced Changes

AbstractGlobal rise in incidence of woody breast (WB) syndrome imposes a significant economic burden on the poultry industry. The increase in WB is due to the large increase in the weight of chickens these days within a very short period. An early determination of WB can significantly reduce losses to the poultry industry. Diffuse reflectance spectroscopy provides a noninvasive and rapid method to interrogate tissue function. The sensitivity of DRS to the distinct absorption spectra of oxygenated and deoxygenated hemoglobin allows accurate quantification of average hemoglobin concentration and vascular oxygenation within the sampled tissue. In this study, we used diffuse reflectance spectroscopy to monitor breast hemoglobin concentration (THb) and vascular oxygen saturation (sO2) of 16 chickens that were exposed to heat stress (HS). HS is an important cause of WB myopathy in chickens. Animals were exposed to heat-stress (HS) and optical data were acquired at three time points: at baseline prior to heat stress, 2 days, and 21 days after initiation of HS. Our results show that animals from control and HS groups had a steady decay in optically derived breast hemoglobin concentration consistent with independent i-STAT measurements made on blood sampled from the femoral artery and could provide a noninvasive technology for monitoring tissue function in the poultry industry.

scholarly journals Diffuse reflectance photometric system for noninvasive blood glucose control

2021 ◽  
Vol 2091 (1) ◽  
pp. 012014
Author(s):  
K V Pozhar ◽  
M O Mikhailov ◽  
E A Polyakova ◽  
E L Litinskaia
Keyword(s):  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Blood Glucose Control ◽  
Biological Tissues ◽  
Reflectance Spectroscopy ◽  
Measuring System ◽  
Photometric System ◽  
Pulsed Mode ◽  
Laser Sources ◽  
Fixed System

Abstract The paper considers the method of diffuse reflectance spectroscopy for noninvasive glucose level measuring in biological tissues. It is proposed a portable implementation of the system, based on a laser diode with a wavelength of 1600 nm and a power of 30 mW, operating in a pulsed mode, as well as a set of NIR-photodiodes located around the laser. The measuring system has been tested on model solutions with diffuse reflectance from polystyrene and pigskin. In the course of measurements on fixed system, an error of ~17 mg/dl is observed, which can be reduced by improving miniature laser sources.

scholarly journals Nondestructive Evaluation of Apple Fruit Quality by Frequency-Domain Diffuse Reflectance Spectroscopy: Variations in Apple Skin and Flesh

2019 ◽  
Vol 9 (11) ◽  
pp. 2355 ◽  
Author(s):  
Nan-Yu Cheng ◽  
Chien-Chih Chen ◽  
Bo-Jian Liang ◽  
Sheng-Hao Tseng
Keyword(s):  
Optical Properties ◽  
Nondestructive Evaluation ◽  
Frequency Domain ◽  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Biological Tissues ◽  
Reflectance Spectroscopy ◽  
Apple Fruit ◽  
Scattering Coefficients

The optical properties of fruits, such as light absorption and scattering characteristics, change with biochemical activities during storage. Diffuse reflectance spectroscopy (DRS) systems have been widely applied for noninvasively observing biological tissues. In this study, we used a frequency-domain DRS system to measure the optical properties of apples. Results showed that variations in the chlorophyll, water, and flesh-texture of apples could be noninvasively monitored over time. We also observed substantial differences in the absorption and reduced scattering coefficients between injured and normal apples. The DRS techniques could be used for apple grading, and, by extension, for monitoring the quality of other fruits.

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