Real-­time parametric estimation of periodic wake-­foil interactions using bioinspired pressure sensing and machine learning

Author(s):  
Wen-Hua Xu ◽  
Guo-Dong Xu ◽  
Lei Shan

Abstract Periodic wake-­foil interactions occur in the collective swimming of bio­inspired robots. Wake interaction pattern estimation (and control) is crucial to thrust enhancement and propulsive efficiency optimization. In this paper, we study the wake interaction pattern estimation of two flapping foils in tandem configurations. The experiments are conducted at a Reynolds number of 1.41×10^4 in a water channel. A modified wake-­foil phase parameter Φ, which unifies the influences of inter­foil distance Lx, motion phase difference ∆φ and wake convection velocity Uv, is introduced to describe the wake interaction patterns parametrically. We use a differential pressure sensor on the downstream foil to capture wake interaction characteristics. Data sets at different tandem configurations are collected. The wake-­foil phase Φ is used to label the pressure signals. A one ­dimensional convolutional neural networks (1D-CNN) model is used to learn an end­to­end mapping between the raw pressure measurements and the wake-­foil phase Φ. The trained 1D-­CNN model shows accurate estimations (average error 3.5%) on random wake interaction patterns and is fast enough (within 40 ms). Then the trained 1D ­CNN model is applied to online thrust enhancement control of a downstream foil swimming in a periodic wake. Synchronous force monitoring and flow visualization demonstrate the effectiveness of the 1D-­CNN model. The limitations of the model are discussed. The proposed approach can be applied to the online estimation and control of wake interactions in the collective swimming and flying of biomimetic robots.

2020 ◽  
pp. 1-17
Author(s):  
Francisco Javier Balea-Fernandez ◽  
Beatriz Martinez-Vega ◽  
Samuel Ortega ◽  
Himar Fabelo ◽  
Raquel Leon ◽  
...  

Background: Sociodemographic data indicate the progressive increase in life expectancy and the prevalence of Alzheimer’s disease (AD). AD is raised as one of the greatest public health problems. Its etiology is twofold: on the one hand, non-modifiable factors and on the other, modifiable. Objective: This study aims to develop a processing framework based on machine learning (ML) and optimization algorithms to study sociodemographic, clinical, and analytical variables, selecting the best combination among them for an accurate discrimination between controls and subjects with major neurocognitive disorder (MNCD). Methods: This research is based on an observational-analytical design. Two research groups were established: MNCD group (n = 46) and control group (n = 38). ML and optimization algorithms were employed to automatically diagnose MNCD. Results: Twelve out of 37 variables were identified in the validation set as the most relevant for MNCD diagnosis. Sensitivity of 100%and specificity of 71%were achieved using a Random Forest classifier. Conclusion: ML is a potential tool for automatic prediction of MNCD which can be applied to relatively small preclinical and clinical data sets. These results can be interpreted to support the influence of the environment on the development of AD.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 286-286
Author(s):  
Anatoliy Yashin ◽  
Dequing Wu ◽  
Konstantin Arbeev ◽  
Arseniy Yashkin ◽  
Galina Gorbunova ◽  
...  

Abstract Persistent stress of external or internal origin accelerates aging, increases risk of aging related health disorders, and shortens lifespan. Stressors activate stress response genes, and their products collectively influence traits. The variability of stressors and responses to them contribute to trait heterogeneity, which may cause the failure of clinical trials for drug candidates. The objectives of this paper are: to address the heterogeneity issue; to evaluate collective interaction effects of genetic factors on Alzheimer’s disease (AD) and longevity using HRS data; to identify differences and similarities in patterns of genetic interactions within two genders; and to compare AD related genetic interaction patterns in HRS and LOADFS data. To reach these objectives we: selected candidate genes from stress related pathways affecting AD/longevity; implemented logistic regression model with interaction term to evaluate effects of SNP-pairs on these traits for males and females; constructed the novel interaction polygenic risk scores for SNPs, which showed strong interaction potential, and evaluated effects of these scores on AD/longevity; and compared patterns of genetic interactions within the two genders and within two datasets. We found there were many genes involved in highly significant interactions that were the same and that were different within the two genders. The effects of interaction polygenic risk scores on AD were strong and highly statistically significant. These conclusions were confirmed in analyses of interaction effects on longevity trait using HRS data. Comparison of HRS to LOADFS data showed that many genes had strong interaction effects on AD in both data sets.


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