scholarly journals The variability of volatile organic compounds in the indoor air of clinical environments

2021 ◽  
Author(s):  
Dahlia Salman ◽  
Wadah Ibrahim ◽  
Amisha Kanabar ◽  
Abigail Joyce ◽  
Bo Zhao ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Indoor Air ◽  
Breath Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Air Contamination ◽  
Breath Testing ◽  
Volatile Organic ◽  
Reliable Interpretation ◽  
The Uk

Abstract The development of clinical breath-analysis is confounded by the variability of background volatile organic compounds (VOC). Reliable interpretation of clinical breath-analysis at individual, and cohort levels requires characterisation of clinical-VOC levels and exposures. Active-sampling with thermal-desorption/gas chromatography-mass spectrometry recorded and evaluated VOC concentrations in 245 samples of indoor air from three sites in a large NHS provider trust in the UK over 27 months. Data deconvolution, alignment and clustering isolated 7344 features attributable to VOC and described the variability (composition and concentration) of respirable clinical VOC. 328 VOC were observed in more than 5% of the samples and 68 VOC appeared in more than 30% of samples. Common VOC were associated with exogenous and endogenous sources and 17 VOC were identified as seasonal differentiators. The presence of metabolites from the anaesthetic sevoflurane, and putative-disease biomarkers in room air, indicated that exhaled VOC were a source of background-pollution in clinical breath-testing activity. With the exception of solvents, and PPE waxes, exhaled VOC concentrations above 3 µg m-3 are unlikely to arise from room air contamination, and in the absence of extensive survey-data, this level could be applied as a threshold for inclusion in studies, removing a potential environmental confounding-factor in developing breath-based diagnostics.

Low temperature headspace desorption of volatile organic compounds trapped in air sampling solid-supports

2009 ◽  
Vol 6 (5) ◽  
pp. 452 ◽  
Author(s):  
Francesc A. Esteve-Turrillas ◽  
Agustín Pastor ◽  
Miguel de la Guardia
Keyword(s):  
Volatile Organic Compounds ◽  
Low Temperature ◽  
Organic Compounds ◽  
Indoor Air ◽  
Gas Chromatography Mass Spectrometry ◽  
Attractive Alternative ◽  
Solid Sorbent ◽  
Solid Supports ◽  
Volatile Organic

Environmental context. The monitoring of volatile organic compounds (VOCs) in air is of great importance for air quality on both local and global scales. The determination of VOCs can be carried out by gas chromatography–mass spectrometry (GC-MS) after active or passive sampling and (high temperature) thermal desorption. An attractive alternative would be to combine GC-MS with headspace (HS) systems as it allows simpler, faster, low temperature desorption. We present here the first report of HS-GC-MS for the determination of VOCs in air sampled using solid supports. Abstract. The use of a headspace (HS) for low temperature desorption of VOCs, previously sorbed from indoor air on solid supports, has been evaluated in order to improve the GC-MS determinations in environmental studies. Graphitised carbon black (GCB), Porapak and Tenax were considered in this study. The HS injector does not allow temperatures higher than 150°C, so there is no a complete desorption of VOCs. However highly volatile compounds were completely desorbed from Porapak and Tenax, but compounds of low volatility showed a strong retention with recoveries of 71–100% for Porapak and 59–100% for Tenax. All studied VOCs were quantitatively desorbed from GCB. Only 100 μL of the HS volume is injected in the chromatographic system. So in spite of the reduced sensitivity we are able to make replicate analyses on the same sampler. Additional experiments were performed using the proposed methodology for the analysis of aforementioned supports in passive and active sampling modes. In short, the proposed methodology reduces the energy consumed and makes it possible to determine the VOCs in air with reduced cost media. The developed methodology permits the determination of 32 VOCs with limits of detection values around 1 μg m–3 when actively sampling air at 50 mL min–1 for 2 h and using 100 mg solid sorbent.

scholarly journals Volatile metabolites of willows determining host discrimination by adult Plagiodera versicolora

2021 ◽  
Author(s):  
Jiahao Ling ◽  
Xiaoping Li ◽  
Guo Yang ◽  
Tongming Yin
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Insect Pests ◽  
Leaf Beetle ◽  
Gas Chromatography Mass Spectrometry ◽  
Host Discrimination ◽  
Plagiodera Versicolora ◽  
Volatile Metabolites ◽  
Hexenyl Acetate ◽  
Volatile Organic

AbstractPlagiodera versicolora Laicharting is a highly damaging leaf beetle foraging on willow leaves. In willow germplasm collections, observation has shown that Salix suchowensis Cheng was severely foraged by this leaf beetle while Salix triandra L. was damage free or only slightly damaged. Results of olfactometer bioassays show that the headspace volatiles from leaves of S. triandra significantly repelled adult beetles, suggesting that this species produces volatile repellents against P. versicolora. S. suchowensis had no effect on the beetles. Gas chromatography-mass spectrometry was carried out to profile the headspace volatile organic compounds and 23 compounds from leaves of the alternate species in significantly different concentrations were detected. The effects of 20 chemical analogs on host discrimination were examined. Olfactory response to these chemicals showed that o-cymene, a S. suchowensis specific constituent, significantly attracted adult P. versicolora. In contrast, cis-3-hexenyl acetate, a constituent concentrated more in S. triandra than in S. suchowensis, significantly repelled beetles. Mixing o-cymene and cis-3-hexenyl acetate in comparable concentrations as in the volatiles of S. suchowensis demonstrated that the latter could mask the attracting effect of the former, causing a neutral response by adult beetles to leaves of S. suchowensis against clean air. In addition, chemical analogs have the same effect as plants when resembling volatile organic compounds in real samples. Two volatile metabolites were detected triggering host discrimination by one of the most damaging insect pests to host and non-host willows. The two metabolites are of considerable potential for use as olfactory signs in managing the beetles.

scholarly journals Volatile Organic Compounds (VOCs) Emitted from Coated Furniture Units

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 806
Author(s):  
Ozge Cemiloglu Ulker ◽  
Onur Ulker ◽  
Salim Hiziroglu
Keyword(s):  
Air Quality ◽  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Indoor Air ◽  
Exposure Period ◽  
Point Of View ◽  
Health Concerns ◽  
Volatile Organic ◽  
Significant Health

Volatile organic compounds (VOCs) are the main source influencing the overall air quality of an environment. It is a well-known fact that coated furniture units, in the form of paints and varnishes, emit VOCs, reducing the air quality and resulting in significant health problems. Exposure time to such compounds is also an important parameter regarding their possible health effects. Such issues also have a greater influence when the exposure period is extended. The main objective of this study was to review some of the important factors for the emission of VOCs from coated furniture, from the perspective of material characteristics, as well as health concerns. Some methods for controlling VOC emissions to improve indoor air quality, from the point of view recent regulations and suggestions, are also presented in this work.

scholarly journals Trichoderma Strains and Metabolites Selectively Increase the Production of Volatile Organic Compounds (VOCs) in Olive Trees

Metabolites ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 213
Author(s):  
Irene Dini ◽  
Roberta Marra ◽  
Pierpaolo Cavallo ◽  
Angela Pironti ◽  
Immacolata Sepe ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Gas Chromatography Mass Spectrometry ◽  
Lipid Signaling ◽  
Plant Interactions ◽  
Growth Promoters ◽  
Volatile Organic ◽  
Trichoderma Fungi ◽  
Olive Trees ◽  
Plant Plant

Plants emit volatile organic compounds (VOCs) that induce metabolomic, transcriptomic, and behavioral reactions in receiver organisms, including insect pollinators and herbivores. VOCs’ composition and concentration may influence plant-insect or plant-plant interactions and affect soil microbes that may interfere in plant-plant communication. Many Trichoderma fungi act as biocontrol agents of phytopathogens and plant growth promoters. Moreover, they can stimulate plant defense mechanisms against insect pests. This study evaluated VOCs’ emission by olive trees (Olea europaea L.) when selected Trichoderma fungi or metabolites were used as soil treatments. Trichoderma harzianum strains M10, T22, and TH1, T. asperellum strain KV906, T. virens strain GV41, and their secondary metabolites harzianic acid (HA), and 6-pentyl-α-pyrone (6PP) were applied to olive trees. Charcoal cartridges were employed to adsorb olive VOCs, and gas chromatography mass spectrometry (GC-MS) analysis allowed their identification and quantification. A total of 45 volatile compounds were detected, and among these, twenty-five represented environmental pollutants and nineteen compounds were related to olive plant emission. Trichoderma strains and metabolites differentially enhanced VOCs production, affecting three biosynthetic pathways: methylerythritol 1-phosphate (MEP), lipid-signaling, and shikimate pathways. Multivariate analysis models showed a characteristic fingerprint of each plant-fungus/metabolite relationship, reflecting a different emission of VOCs by the treated plants. Specifically, strain M10 and the metabolites 6PP and HA enhanced the monoterpene syntheses by controlling the MEP pathway. Strains GV41, KV906, and the metabolite HA stimulated the hydrocarbon aldehyde formation (nonanal) by regulating the lipid-signaling pathway. Finally, Trichoderma strains GV41, M10, T22, TH1, and the metabolites HA and 6PP improve aromatic syntheses at different steps of the shikimate pathway.

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