Developing a Pate with Branch Chain Amino Acids and Identifying It Using a QR Code

RESEARCH which goes to the core of the problem directly and with finesse can elicit admiration. The investigation reported in this issue by Dancis and colleagues will find a number of readers experiencing such appreciation. Hypervalinemia has been reported in only one infant in the world, but rarity is not the reason for its interest; this "experiment of nature," discovered as if by accident, has been a most informative disease. Working with as little as 2 ml of blood taken from the patient, Dancis and colleagues studied the metabolism of valine in the white cells in the sample. The simplicity of the "biopsy" and the elegance of the isotope methods are most exemplary.

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Oral Branch Chain Amino Acids and Encephalopathy

Branched Chain Amino Acids in Clinical Nutrition ◽

10.1007/978-1-4939-1914-7_24 ◽

2014 ◽

pp. 299-311

Author(s):

Lise Lotte Gluud ◽

Gitte Dam ◽

Niels Kristian Aagaard ◽

Hendrik Vilstrup

Keyword(s):

Amino Acids ◽

Branch Chain Amino

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Weight gain, but not macronutrient intake, modifies the effect of dietary branch chain amino acids on the risk of metabolic syndrome

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2020.108039 ◽

2020 ◽

Vol 161 ◽

pp. 108039 ◽

Cited By ~ 1

Author(s):

Somayeh Hosseinpour-Niazi ◽

Zhale Tahmasebinejad ◽

Zohre Esfandiar ◽

Bahar Bakhshi ◽

Parvin Mirmiran ◽

...

Keyword(s):

Metabolic Syndrome ◽

Amino Acids ◽

Weight Gain ◽

Macronutrient Intake ◽

Branch Chain Amino

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The effects of branch-chain amino acids on fatigue in the athletes

Interventional Medicine and Applied Science ◽

10.1556/1646.10.2018.10 ◽

2018 ◽

Vol 10 (4) ◽

pp. 233-235 ◽

Cited By ~ 2

Author(s):

Imanipour Vahid ◽

Banaiifar Abdolali ◽

Mahdi Fatemeh ◽

Naderi Alireza ◽

Sadeghi Mehdi

Keyword(s):

Amino Acids ◽

Branch Chain Amino

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The Emerging role of Branch Chain Amino Acids in the Prediction of Diabetes: A Brief Review

Current Diabetes Reviews ◽

10.2174/1573399815666190502113632 ◽

2020 ◽

Vol 16 (6) ◽

pp. 532-537 ◽

Cited By ~ 1

Author(s):

Shaik Sarfaraz Nawaz ◽

Khalid Siddiqui

Keyword(s):

Insulin Resistance ◽

Type 2 Diabetes ◽

Amino Acids ◽

Causative Factor ◽

Undiagnosed Diabetes ◽

Future Research ◽

Important Approach ◽

Branch Chain Amino ◽

Prediction Of Diabetes

Diabetes is a chronic condition; those with diabetes are at high risk of developing diabetes complications. One important approach to tackle the diabetes burden is to screen for undiagnosed diabetes and to identify factors that lead to the risk of developing diabetes in the future. The earlier identification of individuals at risk of developing diabetes is crucial for delaying or preventing the onset of type 2 diabetes. Numerous studies have demonstrated that circulating concentrations of branch chain amino acids (BCAAs) predict the risk for developing diabetes; thus, contributing to the recent resurgence of interest in these common analytes. The present review aimed to address the recent findings regarding BCAAs and their role in insulin resistance and diabetes. Recent studies demonstrate that BCAAs are strongly associated with a number of pathological mechanisms causing insulin resistance and type 2 diabetes. The research findings related to BCAA signaling pathways and metabolism broaden our understanding of this topic. However, it remains unclear how increased levels of BCAAs will assist in the prediction of future insulin resistance or type 2 diabetes. Future research needs to determine whether BCAAs are a causative factor for insulin resistance and type 2 diabetes, or just a biomarker of impaired insulin action.

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