scholarly journals Considerations for the Use of Human Participants in Vector Biology Research: A Tool for Investigators and Regulators

2015 ◽  
Vol 15 (2) ◽  
pp. 89-102 ◽  
Author(s):  
Nicole L. Achee ◽  
Laura Youngblood ◽  
Michael J. Bangs ◽  
James V. Lavery ◽  
Stephanie James
Author(s):  
Adriana Costero-Saint Denis ◽  
Wolfgang W. Leitner ◽  
Tonu Wali ◽  
Randall Kincaid

2016 ◽  
Vol 110 (4-5) ◽  
pp. 164-172 ◽  
Author(s):  
Alain Kohl ◽  
Emilie Pondeville ◽  
Esther Schnettler ◽  
Andrea Crisanti ◽  
Clelia Supparo ◽  
...  

Insects ◽  
2018 ◽  
Vol 9 (4) ◽  
pp. 139 ◽  
Author(s):  
Jeffrey Powell

The issue of typological versus population thinking in biology is briefly introduced and defined. It is then emphasized how population thinking is most relevant and useful in vector biology. Three points are made: (1) Vectors, as they exist in nature, are genetically very heterogeneous. (2) Four examples of how this is relevant in vector biology research are presented: Understanding variation in vector competence, GWAS, identifying the origin of new introductions of invasive species, and resistance to inbreeding. (3) The existence of high levels of vector genetic heterogeneity can lead to failure of some approaches to vector control, e.g., use of insecticides and release of sterile males (SIT). On the other hand, vector genetic heterogeneity can be harnessed in a vector control program based on selection for refractoriness.


2016 ◽  
Author(s):  
Alain Kohl ◽  
Emilie Pondeville ◽  
Esther Schnettler ◽  
Andrea Crisanti ◽  
Clelia Supparo ◽  
...  

Background: Vector-borne pathogens impact public health and economies worldwide. It has long been recognized that research on arthropod vectors such as mosquitoes, ticks, sandflies and midges which transmit parasites and arboviruses to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is an increasing issue. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies. This has increased interest in vector biology and genetics as well as vector-pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructures will benefit from community input. Methodology/Principal Findings: A survey initiated by the European Horizon2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key issues that should be addressed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such work to be carried out. Conclusions/Significance: We summarize the key findings of the survey which in particular reflect priorities in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations.


1999 ◽  
Author(s):  
Gary Jahns ◽  
Paul Savage ◽  
Teri Schnepp

2020 ◽  
Author(s):  
Shunsuke Ikeda ◽  
Miho Fuyama ◽  
Hayato Saigo ◽  
Tatsuji Takahashi

Machine learning techniques have realized some principal cognitive functionalities such as nonlinear generalization and causal model construction, as far as huge amount of data are available. A next frontier for cognitive modelling would be the ability of humans to transfer past knowledge to novel, ongoing experience, making analogies from the known to the unknown. Novel metaphor comprehension may be considered as an example of such transfer learning and analogical reasoning that can be empirically tested in a relatively straightforward way. Based on some concepts inherent in category theory, we implement a model of metaphor comprehension called the theory of indeterminate natural transformation (TINT), and test its descriptive validity of humans' metaphor comprehension. We simulate metaphor comprehension with two models: one being structure-ignoring, and the other being structure-respecting. The former is a sub-TINT model, while the latter is the minimal-TINT model. As the required input to the TINT models, we gathered the association data from human participants to construct the ``latent category'' for TINT, which is a complete weighted directed graph. To test the validity of metaphor comprehension by the TINT models, we conducted an experiment that examines how humans comprehend a metaphor. While the sub-TINT does not show any significant correlation, the minimal-TINT shows significant correlations with the human data. It suggests that we can capture metaphor comprehension processes in a quite bottom-up manner realized by TINT.


Sign in / Sign up

Export Citation Format

Share Document