scholarly journals Psychological and Biological Pathways Linking Perceived Neighborhood Characteristics and Body Mass Index

2018 ◽  
Vol 53 (9) ◽  
pp. 827-838 ◽  
Author(s):  
Diana A Chirinos ◽  
Luz M Garcini ◽  
Annina Seiler ◽  
Kyle W Murdock ◽  
Kristen Peek ◽  
...  

Abstract Background Perceived neighborhood characteristics are linked to obesity, however, the mechanisms linking these two factors remain unknown. Purpose This study aimed to examine associations between perceived neighborhood characteristics and body mass index (BMI), establish whether indirect pathways through psychological distress and inflammation are important, and determine whether these associations vary by race/ethnicity. Methods Participants were 1,112 adults enrolled in the Texas City Stress and Health Study. Perceived neighborhood characteristics were measured using the Perceived Neighborhood Scale. Psychological distress was measured with the Center for Epidemiological Studies Depression Scale, Perceived Stress Scale and mental health subscale of the Short Form Health Survey-36. Markers of inflammation included C-reactive protein, interleukin-6, and tumor necrosis factor receptor-1. Associations were examined with Structural Equation Modeling. Results A model linking neighborhood characteristics with BMI through direct and indirect (i.e., psychological distress and inflammation) paths demonstrated good fit with the data. Less favorable perceived neighborhood characteristics were associated with greater psychological distress (B = −0.87, β = −0.31, p < .001) and inflammation (B = −0.02, β = −0.10, p = .035). Psychological distress and inflammation were also significantly associated with BMI (Bdistress = 0.06, β = 0.08, p = .006; Binflammation = 4.65, β = 0.41, p < .001). Indirect paths from neighborhood characteristics to BMI via psychological distress (B = −0.05, β = −0.03, p = .004) and inflammation (B = −0.08, β = −0.04, p = .045) were significant. In multiple group analysis, a model with parameters constrained equal across race/ethnicity showed adequate fit suggesting associations were comparable across groups. Conclusion Our study extends the literature by demonstrating the importance of neighborhood perceptions as correlates of BMI across race/ethnicity, and highlights the role of psychological and physiological pathways.

Author(s):  
Brian TaeHyuk Keum ◽  
John L. Oliffe ◽  
Simon M. Rice ◽  
David Kealy ◽  
Zac E. Seidler ◽  
...  

AbstractWe examined whether men’s distress disclosure would be indirectly associated with psychological distress through feeling understood by others and loneliness as serial or parallel mediators. We conducted path analyses (N = 1827 adult men; mean 37.53 years, SD = 14.14) to test the mediators while controlling for race/ethnicity. Post-hoc multi-group analysis was conducted to examine differences across White and Asian men. The serial mediation model fit the data better than the parallel mediation model. Controlling for race/ethnicity, a significant partial indirect association was found between greater distress disclosure and lower psychological distress through greater feelings of being understood and lower feelings of loneliness. Post-hoc multi-group analysis suggested that the hypothesized paths fit equivalently across White and Asian men, and the direct effect was not significant for Asian men. Our hypothesized serial model also fit the data significantly better than alternative models with distress and the mediators predicting disclosure. Distress disclosure may be a socially conducive strategy for men to feel understood and socially connected, a process that may be associated with lower psychological distress.


2007 ◽  
Vol 10 (5) ◽  
pp. 703-711 ◽  
Author(s):  
Ellen L. Goode ◽  
Stacey S. Cherny ◽  
Joe C. Christian ◽  
Gail P. Jarvik ◽  
Mariza de Andrade

AbstractBody-mass index (BMI), total cholesterol (TC), lowdensity lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels are known to be highly heritable. We evaluated the genetic and environmental relationships of these measures over time in an analysis of twin pairs. Monozygotic (235 pairs) and dizygotic (260 pairs) male twins were participants in the National Heart Lung and Blood Institute Veteran Twin Study, and were followed with three clinical exams from mean age 48 years to mean age 63 years. Structural equation modeling (SEM) with adjustment forAPOEgenotype (a significant contributor to TC and LDL-C) was used to assess longitudinal patterns of heritability. Results indicated a contribution of genetic factors to BMI, TC, LDL-C, HLD-C, and TG. Modest increases over time were observed in the heritability of BMI (from 0.48 to 0.61), TC (from 0.46 to 0.57), LDL-C (from 0.49 to 0.64), and HDL-C (from 0.50 to 0.62), but this trend was not present for TG. There was a corresponding decrease in shared environmental influences over time for these traits, although shared environment was a significant contributor only for HDL-C. Moreover, we observed that genetic influences for all measures were significantly correlated over time, and we found no evidence of age-specific genetic effects. In summary, longitudinal analyses of twin data indicate that genetic factors do not account for a significant proportion of the variation in age-related changes of BMI or lipid and lipoprotein levels.


2016 ◽  
Vol 40 (9) ◽  
pp. 1384-1391 ◽  
Author(s):  
K R Smith ◽  
H A Hanson ◽  
B B Brown ◽  
C D Zick ◽  
L Kowaleski-Jones ◽  
...  

2021 ◽  
Author(s):  
Michelle Asinobi ◽  
Cristina Palacios ◽  
Yanyan Wu ◽  
Jinan Banna

Abstract Background: A healthy pre-pregnancy BMI fosters positive outcomes for both mother and infant both during and after pregnancy. To design interventions to promote a healthy pre-pregnancy BMI in low-income women, it is important to understand correlates. The purpose of this study was to identify the socio-demographic correlates of pre-pregnancy body mass index (BMI) among low-income women.Methods: Participants were low-income pregnant women (n=83) in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) program in Hawai‘i enrolled in a four-month text message-based nutrition intervention program. Participants reported pre-pregnancy weight and height and completed a demographics questionnaire on age, race/ethnicity, education, employment status and number of children. Descriptive statistics (mean, standard deviation for continuous variables, and frequencies and proportions for categorical variables) were used to summarize the sample. Simply linear regression analyses were performed to examine if independent variables were associated with BMI before pregnancy. Results: Among the 83 women, 33 (39.8%) were 18-24 years old, 22 (26.5%) were between 25 and 29, 19 (22.9%) were 30-34 and 9 (10.8%) were 35-41. A total of 18 (21.7%) were Asian. Age and race/ethnicity were marginally associated with BMI before pregnancy. The age group 30-34 had the highest BMI before pregnancy (p=0.06) and Asian had lower BMI before pregnancy than the other races/ethnicities (p=0.01). Conclusions: Being classified as Asian was associated with lower BMI before pregnancy, while those who were 30-34 years old had the highest pre-pregnancy BMI compared to other age groups. These socio-demographic factors should be taken into account when designing interventions to promote healthy weight in women of childbearing age. Trial registration: The trial is registered on clinicaltrials.gov (NCT04330976). Date of registration April 2, 2020 (restrospectively registered). URL: https://clinicaltrials.gov/ct2/show/NCT04330976


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Lauren Kupis ◽  
Zachary T. Goodman ◽  
Salome Kornfeld ◽  
Celia Romero ◽  
Bryce Dirks ◽  
...  

Obesity is associated with negative physical and mental health outcomes. Being overweight/obese is also associated with executive functioning impairments and structural changes in the brain. However, the impact of body mass index (BMI) on the relationship between brain dynamics and executive function (EF) is unknown. The goal of the study was to assess the modulatory effects of BMI on brain dynamics and EF. A large sample of publicly available neuroimaging and neuropsychological assessment data collected from 253 adults (18–45 years; mean BMI 26.95 kg/m2 ± 5.90 SD) from the Nathan Kline Institute (NKI) were included (http://fcon_1000.projects.nitrc.org/indi/enhanced/). Participants underwent resting-state functional MRI and completed the Delis-Kaplan Executive Function System (D-KEFS) test battery (1). Time series were extracted from 400 brain nodes and used in a co-activation pattern (CAP) analysis. Dynamic CAP metrics including dwell time (DT), frequency of occurrence, and transitions were computed. Multiple measurement models were compared based on model fit with indicators from the D-KEFS assigned a priori (shifting, inhibition, and fluency). Multiple structural equation models were computed with interactions between BMI and the dynamic CAP metrics predicting the three latent factors of shifting, inhibition, and fluency while controlling for age, sex, and head motion. Models were assessed for the main effects of BMI and CAP metrics predicting the latent factors. A three-factor model (shifting, inhibition, and fluency) resulted in the best model fit. Significant interactions were present between BMI and CAP 2 (lateral frontoparietal (L-FPN), medial frontoparietal (M-FPN), and limbic nodes) and CAP 5 (dorsal frontoparietal (D-FPN), midcingulo-insular (M-CIN), somatosensory motor, and visual network nodes) DTs associated with shifting. A higher BMI was associated with a positive relationship between CAP DTs and shifting. Conversely, in average and low BMI participants, a negative relationship was seen between CAP DTs and shifting. Our findings indicate that BMI moderates the relationship between brain dynamics of networks important for cognitive control and shifting, an index of cognitive flexibility. Furthermore, higher BMI is linked with altered brain dynamic patterns associated with shifting.


2016 ◽  
Vol 33 (3) ◽  
Author(s):  
Cristina Casals ◽  
María Ángeles Vázquez Sánchez ◽  
José Luis Casals Sánchez ◽  
Ernesto Suárez-Cadenas

Introduction: Malnutrition is a serious and relatively common problem among hospitalized patients; moreover, it is known that a good hydration state contributes to health and wellbeing. Objective: The aim of this study was to determine the relationship between nutritional status, functional dependency, quality of life and liquid-intake habits in malnourished patients after hospital discharge. Methods: Cross-sectional descriptive study in 91 patients (45 males) who presented malnutrition at hospital discharge. The patients were grouped according to their liquid intake estimated through the Mini Nutritional Assessment questionnaire: 3-5 glasses (n = 42), and > 5 glasses (n = 46); removing from analysis < 3 glasses of liquid intake (n = 3). The body mass index, weight, Malnutrition Universal Screening Tool (MUST), functional dependency (Barthel questionnaire), and quality of life (Short Form 12 Health Survey [SF-12]) were assessed 2-months after discharge. Results: The > 5 glasses liquid intake group showed better nutritional status than the 3-5 glasses intake group, for weight (p < 0.001), body mass index (p = 0.001), and MUST scale (p = 0.020). Additionally, the > 5 glasses liquid intake group signifi cantly scored higher values in the total SF-12 questionnaire (p = 0.013), presenting better self-reported quality of life, and higher functional independency in the Barthel index (p = 0.037) than the 3-5 glasses liquid intake group (p = 0.013). Conclusions: Although further research is needed to elucidate the characteristics of this relationship, descriptive comparisons between groups showed favorable nutritional status, functional independency and quality of life for the > 5 glasses of liquid intake compared with the 3-5 glasses of liquid intake group during a 2-months follow-up.


Cartilage ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Dean Wang ◽  
Brian J. Rebolledo ◽  
David M. Dare ◽  
Mollyann D. Pais ◽  
Matthew R. Cohn ◽  
...  

Objective To characterize the graft survivorship and clinical outcomes of osteochondral allograft transplantation (OCA) of the knee in patients with an elevated body mass index (BMI). Design Prospective data on 38 consecutive patients with a BMI ≥30 kg/m2 treated with OCA from 2000 to 2015 were reviewed. Complications, reoperations, and patient responses to validated outcome measures were examined. Failures were defined by any removal/revision of the allograft or conversion to arthroplasty. Results Thirty-one knees in 31 patients (mean age, 35.4 years [range, 17-61 years]; 87% male) met the inclusion criteria. Mean BMI was 32.9 kg/m2 (range, 30-39 kg/m2). Mean chondral defect size was 6.4 cm2 (range, 1.0-15.3 cm2). Prior to OCA, 23 patients (74%) had undergone previous surgery to the ipsilateral knee. Mean duration of follow-up was 4.1 years (range, 2-11 years). After OCA, 5 knees (13%) underwent conversion to unicompartmental (1) or total (4) knee arthroplasty. Two- and 5-year graft survivorship were 87% and 83%, respectively. At final follow-up, clinically significant improvements were noted in the pain (49.3-72.6) and physical functioning (52.9-81.3) subscales of the Short Form–36 ( P ≤ 0.001), International Knee Documentation Committee subjective form (43.5-67.0; P = 0.002), Knee Outcome Survey–Activities of Daily Living (58.2-80.4; P = 0.002), and overall condition subscale of the Cincinnati Knee Rating System (4.7-6.9; P = 0.046). Conclusions OCA can be a successful midterm treatment option for focal cartilage defects of the knee in select patients with a BMI ≥30 kg/m2.


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