scholarly journals Lipoprotein secretion by intestinal Caco-2 cells is affected differently by trans and cis unsaturated fatty acids: effect of carbon chain length and position of the double bond

1998 ◽  
Vol 68 (3) ◽  
pp. 561-567 ◽  
Author(s):  
M M van Greevenbroek ◽  
M G Robertus-Teunissen ◽  
D W Erkelens ◽  
T W de Bruin
Keyword(s):  
Fatty Acids ◽  
Double Bond ◽  
Chain Length ◽  
Unsaturated Fatty Acids ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Lipoprotein Secretion

Structural Homogeneity in Unsaturated Fatty Acids of Marine Lipids. A Review

1964 ◽  
Vol 21 (2) ◽  
pp. 247-254 ◽  
Author(s):  
R. G. Ackman
Keyword(s):  
Fatty Acids ◽  
Double Bond ◽  
Polyunsaturated Fatty Acids ◽  
Chain Length ◽  
Unsaturated Fatty Acids ◽  
Analytical Data ◽  
Double Bonds ◽  
Marine Origin ◽  
Methyl Group ◽  
Marine Lipids

Consideration of recent analytical data supports the conclusion that the longer-chain polyunsaturated fatty acids of marine origin are all structurally homogeneous in that the double bonds are cis, the double bonds methylene interrupted, and that, with the exception of the C16 chain length, the ultimate double bond will normally be three, six or nine carbon atoms removed from the terminal methyl group.

scholarly journals SELECTIVITY OF CANDIDA RUGOSA LIPASE IMMOBILIZED ONTO LAYERED DOUBLE HYDROXIDES AS CATALYST IN SYNTHESIS OF FATTY ACID ESTERS

2016 ◽  
Vol 78 (5-6) ◽  
Author(s):  
Mohd Basyaruddin Abdul Rahman ◽  
Siti Salhah Othman ◽  
Noor Mona Md Yunus
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Chain Length ◽  
Candida Rugosa ◽  
Candida Rugosa Lipase ◽  
Carbon Chain ◽  
Fatty Acid Esters ◽  
Carbon Chain Length ◽  
Chain Lengths ◽  
Acid Esters

The enzymatic selectivity of Lipase from Candida rugosa immobilized onto a calcined layered double hydroxide (CLDHs-CRL) towards the chain-length of fatty acids and alcohols in the synthesis of fatty acid esters was investigated.  The results showed that CMAN-CRL catalyzed the esterification process with fatty acids of medium chain lengths (C10-C14) effectively while, CNAN-CRL and CZAN-CRL exhibited high percentage conversion in fatty acids with carbon chain lengths of C8-C12 and C10-C18, respectively. In the alcohol selectivity study, CMAN-CRL showed high selectivity toward alcohols with carbon chain lengths of C4, C6 and C10.  On the other hand, both CNAN-CRL and CZAN-CRL exhibited rather low selectivity towards longer carbon chain length of alcohols. 

Influence of Carbon Chain Length and Unsaturation on the Esterification Activity of Fatty Acids on Nb2O5Catalyst

2009 ◽  
Vol 48 (24) ◽  
pp. 10816-10819 ◽  
Author(s):  
Kalaru Srilatha ◽  
N. Lingaiah ◽  
Potharaju S. Sai Prasad ◽  
B. L. A. Prabhavathi Devi ◽  
R. B. N. Prasad ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Esterification Activity

Carbon Chain Length Modulates MDA‐MB‐231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl−Urea Fatty Acids

ChemMedChem ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. 247-255
Author(s):  
Michael Murray ◽  
Ariane Roseblade ◽  
Yongjuan Chen ◽  
Kirsi Bourget ◽  
Tristan Rawling
Keyword(s):  
Breast Cancer ◽  
Fatty Acids ◽  
Chain Length ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Carbon Chain ◽  
Cell Killing ◽  
Carbon Chain Length

Induction by perfluorinated fatty acids with different carbon chain length of peroxisomal β-oxidation in the liver of rats

2000 ◽  
Vol 124 (2) ◽  
pp. 119-132 ◽  
Author(s):  
Naomi Kudo ◽  
Naoki Bandai ◽  
Erika Suzuki ◽  
Masanori Katakura ◽  
Yoichi Kawashima
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length

scholarly journals Polyenoic very-long-chain fatty acids mobilize intracellular calcium from a thapsigargin-insensitive pool in human neutrophils. The relationship between Ca2+ mobilization and superoxide production induced by long- and very-long-chain fatty acids

1995 ◽  
Vol 311 (2) ◽  
pp. 689-697 ◽  
Author(s):  
S J Hardy ◽  
B S Robinson ◽  
A Ferrante ◽  
C S T Hii ◽  
D W Johnson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Chain Length ◽  
Carbon Chain ◽  
Superoxide Production ◽  
Human Neutrophils ◽  
Carbon Chain Length ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

Fatty acids with more than 22 carbon atoms (very-long-chain fatty acids; VLCFAs) are normal cellular components that have been implicated in the pathophysiology of a number of peroxisomal disorders. To date, however, essentially nothing is known regarding their biological activities. Ca2+ mobilization is an important intracellular signalling system for a variety of agonists and cell types. Given that several polyunsaturated long-chain fatty acids mobilize intracellular Ca2+ and that we have postulated that the VLCFAs may be involved in signal transduction, we examined whether the tetraenoic VLCFA induced Ca2+ mobilization in human neutrophils. We report that fatty acid-induced intracellular Ca2+ mobilization declined for fatty acid species of more than 20 carbon atoms, but increased again as the carbon chain length approached 30. This Ca2+ mobilization occurred independently of inositol 1,4,5-triphosphate production and protein kinase C translocation and involved both the release of Ca2+ from the intracellular stores and changes to the influx or efflux of the ion. We further observed that triacontatetraenoic acid [30:4(n-6)] mobilized Ca2+ from a thapsigargin-insensitive intracellular pool distinct from the thapsigargin-sensitive pools affected by arachidonic acid [20:4(n - 6)] or N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP). 20:4 (n - 6) induced strong superoxide production (chemiluminescence) which was inhibited by thapsigargin pretreatment. In contrast, fatty acid-induced superoxide production progressively declined as the carbon chain length increased beyond 20-22 carbon atoms. Further studies suggested that the thapsigargin-insensitive Ca2+ mobilization elicited by 30:4 (n - 6) was not related to oxyradical formation, while the thapsigargin-sensitive Ca2+ mobilization induced by 20:4 (n - 6) may be involved in the initiation but not necessarily the maintenance of superoxide production. In conclusion, this is the first report to demonstrate a biological activity for the VLCFA and indicates that 30:4 (n - 6) influences second messenger systems in intact cells that differ from those affected by long-chain fatty acids such as 20:4 (n - 6).

STUDIES ON THE IN VITRO ANTITUMOR ACTIVITY OF FATTY ACIDS: V. UNSATURATED ACIDS

1962 ◽  
Vol 40 (7) ◽  
pp. 869-875 ◽  
Author(s):  
Susan Tolnai ◽  
Joseph F. Morgan
Keyword(s):  
Fatty Acids ◽  
Antitumor Activity ◽  
Unsaturated Fatty Acids ◽  
Relative Effectiveness ◽  
Carbon Chain ◽  
Ehrlich Carcinoma ◽  
Carbon Chain Length ◽  
Ascites Tumors ◽  
Arachidonic Acids

Previous studies on the in vitro antitumor activity of saturated mono- and dicarboxylic fatty acids have been extended to a series of unsaturated fatty acids ranging in carbon chain length from C6to C20- All 10 compounds tested exhibited some activity at pH 4.0 against the ascites forms of the Ehrlich carcinoma, 6C3HED lymphosarcoma, and TA3mammary carcinoma. Only three compounds (2-decenoic, linoleic, and linolenic acids) were found to be active at neutrality against all three tumors, while four compounds (2-nonenoic, 10-undecenoic, oleic, and arachidonic acids) were active against one or two tumors under neutral conditions. Considerable variations were encountered in the relative effectiveness of these compounds against the three ascites tumors. The compounds with the most marked in vitro antitumor activity were linoleic and linolenic acids.

scholarly journals Effect of Carbon Chain Length of Fatty Acids on Ketogenesis in the Ruminant

1968 ◽  
Vol 51 (7) ◽  
pp. 1094-1097 ◽  
Author(s):  
S. Yamdagni ◽  
L.H. Schultz ◽  
H.D. Radloff
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length
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