A Rare Case of Cavernous Angiomatosis of the Uterus

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S79-S79
Author(s):  
V Prakash ◽  
C E Middleton ◽  
V Shenoy
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
English Literature ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Abnormal Uterine Bleeding ◽  
Accurate Diagnosis ◽  
Vascular Tumors ◽  
Unexpected Finding ◽  
Female Genital

Abstract Introduction/Objective Angiomatosis is a rare, non-neoplastic vascular malformation characterized by the proliferation of blood vessels which involve skin, soft tissue, and bone. Angiomatosis of the female genital tract is extremely rare with very few cases described in the English literature. Methods/Case Report We present a case of an unexpected finding of angiomatosis of the uterus and cervix in a 34- year-old nulliparous female with a history of abnormal uterine bleeding and dysmenorrhea of one year duration. Imaging studies showed an anteverted uterus measuring 9 cm × 6 cm × 5 cm with thickened irregular endometrium, blood clots within the endometrial cavity, and subserosal uterine fibroids. A subsequent endometrial curettage showed benign superficial endometrium. Hysterectomy was performed and histopathological examination revealed diffuse haphazardly arranged large vascular channels within the uterine wall and cervical stroma. A diagnosis of cavernous angiomatosis of the uterus and cervix was made. Results (if a Case Study enter NA) NA Conclusion Angiomatosis of the female genital tract is a rare vascular proliferation that tends to grow at a slow rate and cause heavy menstrual bleeding in otherwise healthy patients. Differential diagnoses of angiomatosis include other vascular tumors such as hemangiomas, lymphangioma, arteriovenous malformation and papillary endothelial hyperplasia. Clinical examination and investigations like hysteroscopy, endometrial curettage and ultrasonography may not help in accurate diagnosis. Definitive diagnosis relies heavily on histopathological examination. Treatment of symptomatic angiomatosis is purely surgical and in our case, was curative. Following treatment, recurrences can occur and appropriate surveillance is recommended. Malignant transformation have not been reported. It is important to be aware of this rare entity to make an accurate diagnosis.

scholarly journals Cervical superficial myofibroblastoma: Case report and review of the literature

2017 ◽  
Vol 5 ◽  
pp. 2050313X1772693
Author(s):  
Mohamed Abdelaziz ◽  
Noura Eziba ◽  
Suash Sharma ◽  
Daniel Kleven ◽  
Ayman Al-Hendy
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Smooth Muscle Actin ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Review Of The Literature ◽  
Cervical Mass ◽  
Submucosal Mass ◽  
Mass Lesions ◽  
Female Genital

Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells. An immunohistochemistry evaluation revealed reactivity for CD34, desmin, and smooth muscle actin. This neoplasm should be included in the differential diagnosis of cervical mass lesions. This tumor also needs to be differentiated from other mesenchymal lesions of lower female genital tract.

scholarly journals Spectrum of histopathological lesions in the fallopian tubes

2013 ◽  
Vol 3 (5) ◽  
pp. 356-360 ◽  
Author(s):  
S Gon ◽  
A Basu ◽  
B Majumdar ◽  
TK Das ◽  
M Sengupta ◽  
...  
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Secondary Malignancies ◽  
Fallopian Tubes ◽  
Serial Sections ◽  
Pathology Laboratory ◽  
Surgical Specimen ◽  
Neoplastic Lesions ◽  
Female Genital

Background: Fallopian tubes are common surgical specimen in the pathology laboratory; still there is a lack of data to describe the frequency of various histological fi ndings. The aim and objectives of this study was to describe the various histopathological fi ndings of fallopian tubes. Materials and Methods: Two thousand fi ve hundred and seventy fi ve cases where fallopian tubes were removed either separately or along with other female genital tract organs were studied retrospectively and their histopathological fi ndings documented. Results: Ectopic pregnancy comprised maximum number of cases closely followed by salpingitis. Primary neoplastic lesions were rare as compared to secondary malignancies. Serial sections of fallopian tube and sections from representative areas are essential for a pathologist so that the diagnosis of these pathological entities is not missed. Conclusion: Though the fallopian tubes remain unremarkable in majority of the surgical pathological specimens, it must be subjected for histopathological examination to demonstrate the pathological lesions. Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 356-360 DOI: http://dx.doi.org/10.3126/jpn.v3i5.7858

Benign vascular tumors of female genital tract

2006 ◽  
Vol 16 (3) ◽  
pp. 1195-1200 ◽  
Author(s):  
R. Gupta ◽  
S. Singh ◽  
S. Nigam ◽  
N. Khurana
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Special Problem ◽  
Vascular Lesions ◽  
Vascular Tumors ◽  
Pregnancy Risk ◽  
Duration Of Symptoms ◽  
Clinical Diagnoses ◽  
Microscopic Features ◽  
Female Genital

Vascular tumors are rare in female genital tract (FGT). The aim of this study was to analyze the distribution of vascular tumors in FGT and to highlight their clinicopathologic features. As a retrospective study, clinical features including imaging studies, gross findings, and microscopic features of cases (ten) diagnosed as having vascular tumors of FGT over 4 years were reviewed. The age range of our cases was 12–52 years. The presenting complaint was abdominal pain/mass, postcoital bleeding, and vaginal and vulval mass. In most cases, duration of symptoms was 6 months to 2 years. Only one case had a long-standing history of 8 years. The vascular tumors occurred most commonly in ovary (six), followed by vulva (two), and one each in cervix and vagina. Clinical diagnoses ranged from cystadenoma in ovarian tumors to endocervical polyp in cervical tumor. Histologically, all were benign vascular neoplasms, ranging from hemangioma (five), lymphangioma (one), lymphangioma circumscriptum (one) to angiomatosis (two) and arteriovenous malformation (one). Thus, we conclude that vascular lesions in FGT can present with symptoms similar to epithelial malignancies and may lead to unwarranted radical surgery. Vascular lesions of cervix and vulvovaginal region pose special problem during pregnancy. Risk of Kasabach–Merritt coagulopathy has to be considered in larger vascular tumors. Most of these cases can be treated by surgery.

scholarly journals Xanthogranulomatous Endometritis: A Challenging Imitator of Endometrial Carcinoma

2007 ◽  
Vol 2007 ◽  
pp. 1-3 ◽  
Author(s):  
A. Işın Doğan-Ekici ◽  
Alp Usubütün ◽  
Türkan Küçükali ◽  
Ali Ayhan
Keyword(s):  
Endometrial Carcinoma ◽  
Genital Tract ◽  
Plasma Cells ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Giant Cells ◽  
Polymorphonuclear Leucocytes ◽  
Xanthogranulomatous Inflammation ◽  
Post Menopausal ◽  
Female Genital

Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin. We present a case of a 69-year-old female complained of post menopausal bleeding and weight loss. Clinical preliminary diagnoses were endometrial carcinoma or hyperplasia and ultrasound was supposed to be endometrial malignancy, hyperplasia or pyometra by radiologist. Histopathological examination of uterus revealed xanthogranulomatous endometritis. Since xanthogranulomatous endometritis may mimic endometrial malignancy clinically and pathologically as a result of the replacement of the endometrium and occasionally invasion of the myometrium by friable yellowish tissue composed of histiocytes, knowledge of this unusual inflammatory disease is needed for both clinicians and pathologists.

scholarly journals Hydatid cyst of broad ligament: a rare case report

2020 ◽  
Vol 7 (4) ◽  
pp. 1298
Author(s):  
Ajay Gujar ◽  
Jayant Pednekar ◽  
Nida Khan ◽  
Anurag Tiwary ◽  
Rohith Pillai ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Genital Tract ◽  
Histopathological Examination ◽  
Broad Ligament ◽  
Female Genital Tract ◽  
Surgical Excision ◽  
Cystic Mass ◽  
Rare Case Report ◽  
Peculiar Case ◽  
Female Genital

Hydatid cyst is a parasitic disease caused by tapeworm Echinococcus. It affects the liver and lung most commonly, but may rarely affect fallopian tube, broad ligament and other structures. One such peculiar case is where a 17 years old female presented with a rapidly growing cystic mass in lower abdomen, clinically suspicious of ovarian mass or mesentric cyst. Investigations failed to identify the nature. On laparotomy, excision of the mass was done. Suprisingly histopathological examination identified the lesion as hydatid cyst arising from the broad ligament. Patient responded well to surgical excision followed by albendazole administration. Female genital tract hydatidosis is a rare entity and in most cases the involvement is secondary. Primary hydatid disease of female genital tract is even very rarer and generates considerable diagnostic difficulty.

scholarly journals Ovarian enterobiasis: a case report

2018 ◽  
Vol 6 (3) ◽  
pp. 1055 ◽  
Author(s):  
Geethu G. Nair ◽  
Prejisha Balan
Keyword(s):  
Gastrointestinal Tract ◽  
Cross Section ◽  
Genital Tract ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Female Genital Tract ◽  
Inflammatory Cells ◽  
Enterobius Vermicularis ◽  
Intestinal Nematode ◽  
Female Genital

Enterobius vermicularis (the pinworm) is the most common intestinal nematode in gastrointestinal tract of humans. It commonly infests the lumen of the intestine but on rare occasions has been found in the wall or in the tissues outside the gastrointestinal tract; female genital tract and peritoneum being the commonest sites. It is usually seen as an incidental finding. This is a case of 29-year-old female presented for elective sterilization. A tiny nodule was noted on the surface of ovary during procedure which was sent for histopathological examination. Lesion was composed of necrotic areas and inflammatory cells with cross section of a degenerated worm. The features of the eggs were diagnostic of Enterobius vermicularis. Multiple histologic sections may be required to establish diagnosis in older lesions as in this case.

An audit of the clinicopathological spectrum of benign vascular tumors of female genital tract; with a mini narrative review

2016 ◽  
Vol 5 (1) ◽  
pp. 33
Author(s):  
SainathK Andola ◽  
ShruthiS Andola ◽  
Vatsala Kishore ◽  
KruthikaS Andola ◽  
UmadeviS Andola
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Narrative Review ◽  
Vascular Tumors ◽  
Female Genital

scholarly journals A Case of Primary Uterina Lymphoma Presenting with Bleeding, Pelvic Pain, and Dysmenorrhea

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Lilian Yukari Miura ◽  
Miriam Anyury Daquin Maure ◽  
Monica Tessmann Zomer ◽  
Reitan Ribeiro ◽  
Teresa Cristina Santos Cavalcanti ◽  
...  
Keyword(s):  
Pelvic Pain ◽  
Genital Tract ◽  
Transvaginal Ultrasound ◽  
Female Genital Tract ◽  
Abnormal Uterine Bleeding ◽  
Laparoscopic Hysterectomy ◽  
Primary Lymphoma ◽  
Female Population ◽  
Histologic Evaluation ◽  
Female Genital

Primary non-Hodgkin’s lymphoma (NHL) can arise from lymphatic cells located in solid organs (extranodal) and it accounts for 25 to 35% of all NHL. Primary lymphoma on the female genital tract (PLFGT) is a rare disease, comprising 0.2 to 1.1% of all extranodal lymphomas in the female population. In this paper, the authors report an extremely rare case of a 48-year-old woman who exhibited an abnormal uterine bleeding, pelvic pain, and dysmenorrhea history. The transvaginal ultrasound showed an anteverted uterus measuring 153 cm3 in volume, with intramural leiomyomas. She underwent a total laparoscopic hysterectomy with bilateral salpingectomy. The histologic evaluation of the specimen showed a follicular lymphoma with diffuse pattern in the endometrium. This report illustrates the difficulty in the diagnosis of primary lymphomas of the female genital tract.

Angiosarcomas of Primary Gynecologic Origin: A Clinicopathologic Review and Quantitative Analysis of Survival

2014 ◽  
Vol 24 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Arnold-Jan Kruse ◽  
Simone Sep ◽  
Brigitte F.M. Slangen ◽  
Nathalie M. Vandevijver ◽  
Toon Van Gorp ◽  
...  
Keyword(s):  
Genital Tract ◽  
Cox Regression ◽  
English Literature ◽  
Female Genital Tract ◽  
Primary Treatment ◽  
Demographic Variables ◽  
Cox Regression Analysis ◽  
Kaplan Meier ◽  
Malignant Soft Tissue ◽  
Female Genital

ObjectiveAngiosarcomas are aggressive, malignant soft tissue neoplasms of endothelial origin and occur rarely in the female genital tract. There is lack of consensus on risk factors for poor outcome and optimal treatment. To this end, we performed a clinicopathologic review and survival analysis.MethodsWe report a case of a woman with an angiosarcoma of the vagina. Published English literature was reviewed for angiosarcomas of the vulva, vagina, uterus, and ovary. Survival was evaluated by using Kaplan-Meier analysis and the effect of clinical and demographic variables on survival by using Cox regression analysis.ResultsA total of 51 patients were identified with a median age of 47 years (range, 17–87 years). Two of the patients had an angiosarcoma of the vulva; 2 had an angiosarcoma of the vagina; 18 had an angiosarcoma of the uterus, and 29 had an angiosarcoma of the ovary. Five-year overall survival was 27% (SE, 8%). Most patients presented with locoregional disease, having surgery as their primary intervention. Overall, adjuvant therapy significantly improved survival (hazards ratio, 0.17; 95% confidence interval, 0.05–0.59; adjusted for age and tumor size). Adjuvant treatment consisted of radiotherapy for angiosarcomas of the vulva, vagina, and uterus and chemotherapy for ovarian angiosarcomas. Subgroup analysis of the female genital tract site was hampered by the small number of cases.ConclusionsThis review supports the use of surgical and adjuvant radiotherapy for angiosarcomas of the vulva, vagina, and uterus. Cytoreductive surgery and adjuvant chemotherapy remain the primary treatment of angiosarcomas of the ovary.

scholarly journals Abnormal Contour Huge Uterine Fibroids

2016 ◽  
Vol 27 (2) ◽  
pp. 49-50
Author(s):  
Parveen Ahmed ◽  
GM Farid ◽  
Tanveen Ishague ◽  
Ayesha Siddiqua
Keyword(s):  
Genital Tract ◽  
Benign Tumor ◽  
Female Genital Tract ◽  
Uterine Fibroids ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Pelvic Ultrasound ◽  
Benign Leiomyoma ◽  
History Of ◽  
Female Genital

Uterine fibroids represent the most common large solid benign tumor of the female genital tract. This 35 years old lady, mother of one child represented to our clinic with a history of progressive abdominal swelling that had rapidly increased in the last two years. There were associated abdominal pain, easy fatigability, heavy menstrual loss and prolong secondary subfertility of about ten years. On examination abdomen was enlarged and the mass measuring about 25cm from xiphisternum, firm, irregular and fairly mobile. Pelvic ultrasound scan revealed features of huge multiple uterine fibroids and the size of the largest one was about 20x25cm,moderate bilateral hydro-nephrosis. Intraoperative findings were moderate pelvic adhesions, huge multiple fibroids and the largest measuring about 18x20cm. Total abdominal hysterectomy with preservation of both ovaries were done. Histopathological report confirmed benign leiomyoma with no evidence of malignancy.Medicine Today 2015 Vol.27(2): 49-50

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