scholarly journals Gastric cancer in young patients: Prognostics factors and therapeutic results

2017 ◽  
Vol 28 ◽  
pp. iii18
Author(s):  
Mariem Benhami ◽  
Hajar Ouahbi ◽  
Layla El Achhab ◽  
Lamia Amaadour ◽  
Zineb Benbrahim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Young Patients ◽  
Therapeutic Results ◽  
Prognostics Factors

scholarly journals Clinicopathological Features and Prognosis of Gastric Cancer in Young Patients

2020 ◽  
Vol 23 (4) ◽  
pp. 161-162
Author(s):  
Ki Bum Park ◽  
Kyong Hwa Jun
Keyword(s):  
Gastric Cancer ◽  
Young Patients ◽  
Clinicopathological Features

scholarly journals Ethnic and racial disparities among young patients with noncardia gastric cancer

2018 ◽  
Vol 29 ◽  
pp. v25 ◽  
Author(s):  
C. Hester ◽  
A. Yopp ◽  
P. Polanco ◽  
J. Mansour ◽  
S. Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Racial Disparities ◽  
Young Patients

scholarly journals A systemic review and meta-analysis for prognostic values of pretreatment lymphocyte-to-monocyte ratio on gastric cancer

2019 ◽  
Vol 17 ◽  
pp. 205873921983109
Author(s):  
Zhigui Li ◽  
Zhaofen Xu ◽  
Yuqian Huang ◽  
Yong Wang ◽  
Hare Ram Karn ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Outcomes ◽  
Cancer Progression ◽  
Meta Analysis ◽  
Prognostic Significance ◽  
Young Patients ◽  
Systemic Review ◽  
Cochrane Library ◽  
Low Level ◽  
Lymphocyte To Monocyte Ratio

The systemic inflammation plays a crucial role in carcinogenesis and cancer progression. Pretreatment lymphocyte-to-monocyte ratio (LMR) has been suggested to be associated with clinical outcomes in various malignancies. To evaluate the prognostic significance of pretreatment LMR on gastric cancer, we conducted a comprehensive literature search in PubMed, Embase, Web of Science, Cochrane Library, and ClinicalTrials.gov (Prospero Registration No. CRD42018087263). This meta-analysis included all studies evaluating the prognostic significance of pretreatment LMR on gastric cancer. The main outcome measures included overall survival (OS), progression-free survival (PFS), and the relationship between LMR and clinicopathological features. In total, 11 studies (12 cohorts) enrolling 14,262 patients with gastric cancer were included. The pooled estimates showed that elevated pretreatment LMR was significantly associated with better OS (hazard ratio (HR): 0.71, 95% confidence interval (CI): 0.58–0.83) and better PFS (HR: 0.71, 95% CI: 0.44–0.99). The elevated LMR was also significantly associated with young patients, female, low level of carcinoembryonic antigen (CEA), low level of carbohydrate antigen 19-9 (CA19-9), stage I–II, small tumor size, absence of lymph node metastasis, absence of vascular invasion, and absence of perineural invasion. In conclusion, the elevated pretreatment LMR predicted the better clinical outcomes in patients with gastric cancer.

Is Laparoscopic Gastrectomy More Advantageous for Elderly Patients Than for Young Patients with Resectable Advanced Gastric Cancer?

2020 ◽  
Vol 44 (7) ◽  
pp. 2332-2339
Author(s):  
Yuki Ushimaru ◽  
Yukinori Kurokawa ◽  
Tsuyoshi Takahashi ◽  
Takuro Saito ◽  
Kotaro Yamashita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Laparoscopic Gastrectomy ◽  
Young Patients

scholarly journals Gastric cancer in young patients

2018 ◽  
Vol 29 ◽  
pp. viii233-viii234
Author(s):  
M.M. Seker ◽  
A. Bahceci ◽  
T. Kacan
Keyword(s):  
Gastric Cancer ◽  
Young Patients

Gastric cancer in young patients: a separate entity with aggressive features and poor prognosis

2020 ◽  
Vol 146 (11) ◽  
pp. 2937-2947
Author(s):  
Lyujia Cheng ◽  
Songyao Chen ◽  
Wenhui Wu ◽  
Zi Chong Kuo ◽  
Zhewei Wei ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Poor Prognosis ◽  
Young Patients ◽  
Separate Entity

Clinical Outcomes and the Role of Adjuvant Concurrent Chemoradiation Therapy in D2-resected LN-positive Young Patients (≤45 Years) With Gastric Cancer

2019 ◽  
Vol 39 (10) ◽  
pp. 5811-5820 ◽  
Author(s):  
JEONG IL YU ◽  
DO HOON LIM ◽  
JEEYUN LEE ◽  
WON KI KANG ◽  
SE HOON PARK ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Outcomes ◽  
Young Patients ◽  
Chemoradiation Therapy ◽  
Concurrent Chemoradiation ◽  
Concurrent Chemoradiation Therapy

PS01.162: IS THERE A DIFFERENCE IN SURVIVAL BETWEEN YOUNGER AND OLDER GASTRIC CANCER (INCLUDING AEG II AND AEG III) PATIENTS AFTER GASTRECTOMY?

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 95-95
Author(s):  
Benjamin Babic ◽  
Florian Matthias Corvinus ◽  
Edin Hadjijusufovic ◽  
Evangelos Tagkalos ◽  
Hauke Lang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Elderly Patients ◽  
Conflicts Of Interest ◽  
Subtotal Gastrectomy ◽  
Young Patients ◽  
Western World ◽  
Old Patients ◽  
Younger Patients ◽  
Significant Difference

Abstract Background The incidence of gastric cancer decreases in the western world, however, it remains one of the most common diseases (1). There is just little data from Europe comparing the outcome of young and elderly gastric cancer patients. This study compares, depending on the age of 266 patients, the outcome of 266 consecutive gastrectomy cases due to gastric cancer Methods 266 consecutive patients with gastric cancer received a gastrectomy between 2008–2016 at our comprehensive cancer centre. The mean age of the patients in this study was 64 years old (21- 93 years). All patients were followed up regarding survival. The patients were separated in 6 different groups, depending on the age at the time of operation. The different groups were re-analysed and compared to each other regarding median and 5-year survival. Results In this collective the 5-year survival rate for all patients was 43%. There were more diffuse type adenocarcinomas in Patients < 40 years. In younger patients the tumour was staged in an advanced stadium compared to the elderly patients group. There is a significantly higher 5-year survival rate for younger patients after gastrectomy. There is no significant difference, when separating patient groups in to decades of age. Conclusion Young patients have a higher 5-year survival rate after gastrectomy compared to old patients. However, comparing patients from chronologic age in decades, the significance is not reproducible. Therefore gastrectomy or subtotal gastrectomy is the determining therapeutic approach for gastric cancer with an acceptable outcome in both young and elderly patients. Older patients might have an lower 5 year survival rate not only due to the cancer or the surgical therapy itself, it is related to comorbidities and a lower rate in neoadjuvant therapy as well Disclosure All authors have declared no conflicts of interest.

scholarly journals Higher Risk of Lymph Node Metastasis in Young Patients with Early Gastric Cancer

2019 ◽  
Vol 10 (18) ◽  
pp. 4389-4396 ◽  
Author(s):  
Zu-Kai Wang ◽  
Jian-Xian Lin ◽  
Ping Li ◽  
Jian-Wei Xie ◽  
Jia-Bin Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Young Patients ◽  
Node Metastasis

Divergent Outcomes in Young Patients With Gastric Cancer

2013 ◽  
Vol 179 (2) ◽  
pp. 293
Author(s):  
D.K. Nguyen ◽  
M. Maggard-Gibbons
Keyword(s):  
Gastric Cancer ◽  
Young Patients
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