Phosphomatics: interactive interrogation of substrate–kinase networks in global phosphoproteomics datasets
Abstract Motivation Mass spectrometry-based phosphoproteomics can routinely identify and quantify thousands of phosphorylated peptides from a single experiment. However interrogating possible upstream kinases and identifying key literature for phosphorylation sites is laborious and time-consuming. Results Here, we present Phosphomatics—a publicly available web resource for interrogating phosphoproteomics data. Phosphomatics allows researchers to upload phosphoproteomics data and interrogate possible relationships from a substrate-, kinase- or pathway-centric viewpoint. Availability and implementation Phosphomatics is freely available via the internet at: https://phosphomatics.com. Supplementary information Supplementary data are available at Bioinformatics online.