An “artificial tongue” for calibrating solution flow characteristics of taste stimulus delivery systems

Pore-throat ratio is a significant parameter expressing the characteristics of reservoir pores. It has an apparent influence on viscoelastic polymer solution flow in micro-pores. In this article, Upper-Convected Maxwell (UCM) equation is adapted to describe the viscoelastic polymer behavior. The contraction channel models of different pore-throat ratio are selected in process of simulation. And contours of stream function and velocity of different Weissenberg number (We) are calculated and drawn by Finite Volume Method. Results show that, vortex will occur at the re-entrant corner caused by the sudden contraction of channel, size and intensity of the corner recirculation vortex. The residual oil region is reduced and the mobile oil region is enlarged. Microscopic sweep efficiency is increased relatively. Vortex will be larger and stronger, and the velocity will be increased for We. Vortex will be lager with the bigger pore-throat ratio. Micro-sweep efficiency will be capitalized by viscoelastic polymer solution to the utmost.

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Flow Characteristics of Viscoelastic Polymer Solution in Expansion Micro-Pores of Different Pore-Throat Ratio

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.268-270.1119 ◽

2012 ◽

Vol 268-270 ◽

pp. 1119-1122 ◽

Cited By ~ 1

Author(s):

Jing Fu

Keyword(s):

Polymer Solution ◽

Flow Characteristics ◽

Weissenberg Number ◽

Sudden Expansion ◽

Pore Throat ◽

Sweep Efficiency ◽

Solution Flow ◽

Viscoelastic Polymer ◽

Volume Method ◽

Apparent Influence

Pore-throat ratio is a significant parameter expressing the characteristics of reservoir pores. It has an apparent influence on viscoelastic polymer solution flow in micro-pores. In this paper, Upper-Convected Maxwell (UCM) equation is applied in describing the viscoelastic polymer behavior. The expansion channel models of different pore-throat ratio are selected in process of simulation. And contours of stream function and velocity of different Weissenberg number (We) are calculated and drawn by Finite Volume Method. Results show that, vortex will occur at the re-entrant corner caused by the sudden expansion of channel, size and intensity of the corner recirculation vortex. The residual oil region is reduced and the mobile oil region is enlarged. Microscopic sweep efficiency is increased relatively. Vortex will be larger and stronger, and the velocity will be increased for We. Vortex will be lager as the bigger pore-throat ratio. Micro-sweep efficiency will be capitalized by viscoelastic polymer solution to the utmost.

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Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100120242 ◽

1985 ◽

Vol 43 ◽

pp. 710-711

Author(s):

G.E. Visscher ◽

R. L. Robison ◽

G. J. Argentieri

Keyword(s):

Drug Delivery ◽

Drug Delivery Systems ◽

Gastrocnemius Muscle ◽

Degradation Process ◽

Delivery Systems ◽

Tissue Reaction ◽

Electron Microscopic ◽

Tissue Samples ◽

Injectable Polymer ◽

Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

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