A list of selected reference materials in clinical chemistry.

1977 ◽  
Vol 23 (1) ◽  
pp. 143-145 ◽  
Author(s):  
J M Airall
Keyword(s):  
Reference Materials ◽  
Analytical Methods ◽  
Clinical Laboratory ◽  
Clinical Chemistry ◽  
Library Collection ◽  
Reference Collection ◽  
Laboratory Reference

Abstract This is a compilation of reference materials suggested for scientists considering a laboratory reference collection in clinical chemistry, or for librarians seeking to develop or add to an up-t-o-date library collection. Nine areas are represented: general clinical chemistry; analytical methods, procedures, and techniques; calculations and statistics; the clinical laboratory; drugs and metabolism; enzymology; instrumentation, interpretation of data; and ready reference.

scholarly journals Update and clinical management of anti-DNA auto-antibodies

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Concepción González Rodríguez ◽  
MªBelén Aparicio Hernández ◽  
Inmaculada Alarcón Torres
Keyword(s):  
Lupus Erythematosus ◽  
Analytical Methods ◽  
Clinical Laboratory ◽  
Meta Analysis ◽  
Laboratory Methods ◽  
Wide Variability ◽  
Diagnostic Usefulness ◽  
Dna Antibodies ◽  
Editorial Review

Abstract Objectives Anti-deoxyribonucleic acid (DNA) antibodies in the clinical laboratory are intimately linked to the diagnosis and monitoring of systemic lupus erythematosus (SLE); however, the characteristics of the analytical methods and the properties of the antibodies themselves are heterogeneous. To review the definition and properties of anti-double-stranded anti-DNA (anti-dsDNA) antibodies, the adequacy of analytical methods, and the clinical requirements for this biomarker. Content Through PubMed we searched the existing literature with the terms anti-dsDNA, editorial, review, guideline, meta-analysis and SLE. The last search, anti-dsDNA and SLE restricted to the last two years. Information was expanded through related articles and those published in official state bodies related to anti-dsDNA and SLE. Summary Clinical laboratory methods for anti-dsDNA analysis and their characteristics are analyze. The clinical utility of anti-dsDNA in its diagnostic, clinical association and follow-up aspects of SLE is reviewed. Outlook There is wide variability in analytical methods and deficits in standardization persist. They are part of the current SLE classification criteria and are used as markers in the follow-up of the disease. Their diagnostic usefulness improves when they are determined in antinuclear antibody (ANA)-positive patients. In follow-up, quantification is of interest, preferably with the same analytical method (given the deficits in standardization).

scholarly journals "E-books are good if there are no copies left": a survey of e-book usage at UWE Library Services

2009 ◽  
Vol 33 (104) ◽  
pp. 45-65 ◽  
Author(s):  
Jacqueline Ann Chelin ◽  
Jason Briddon ◽  
Elspeth Williams ◽  
Jane Redman ◽  
Alastair Sleat ◽  
...  
Keyword(s):  
Reference Materials ◽  
Academic Staff ◽  
Academic Library ◽  
Library Services ◽  
Considerable Effort ◽  
Teaching And Research ◽  
Library Collection ◽  
Learning And Teaching ◽  
The Impact ◽  
Subject Coverage

This article outlines research carried out with students and academic staff at a large UK university library on how e-books are being used for learning, teaching and research. It was discovered that e-books are meeting many of users' needs, especially in terms of accessibility, but there are still concerns about subject coverage and the impact on students' learning. There are various reasons why e-books are beneficial in developing an academic library collection, most particularly for reference materials and essential readings, but librarians need to work closely with academic staff to integrate use of e-books effectively into learning and teaching, taking care that licence and access implications are better understood. The drivers to the use of e-books appear to be outweighing the barriers, although the latter will require considerable effort on the part of librarians within their institutions and also in terms of communicating concerns to e-book providers.

scholarly journals A review: Analytical methods for heavy metals determination in environment and human samples

2019 ◽  
pp. 97-126 ◽  
Author(s):  
Mojtaba Arjomandi ◽  
*Hamid Shirkhanloo
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Human Health ◽  
Human Body ◽  
Analytical Methods ◽  
Review Paper ◽  
Clinical Chemistry ◽  
Daily Lives ◽  
Soil And Water

Heavy metals are vital and necessary in our daily lives. Moreover, if the amounts of heavy metals are more than the acceptable amounts (mentioned by WHO) in soil, water, and air, indeed, they cause a lot of diseases in human bodies. Therefore, monitoring and measuring the amounts of heavy metals that are arduous and difficult are so important. In this review paper, a lot of studies that have been carried out on the determination and quantification of heavy metals in human bodies, soil, and water are considered. Moreover, the effect of toxicity of each heavy metal on human health is assessed. According to WHO, EPA, NIOSH, ACGIH, and clinical chemistry, the determination of heavy metals such as Cd, Pb, Zn, Hg, Cu, Mn is very important in the human body and Environmental matrixes. 

Analytical Methods and Development of Reference Materials for Toxic Metals and Metal Species in Food and Dietary Supplements

2017 ◽  
pp. 639-678
Author(s):  
Stephen E. Long ◽  
Michael Ellisor ◽  
Frances Nilsen ◽  
Laura Wood ◽  
Karen Murphy ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Reference Materials ◽  
Toxic Metals ◽  
Analytical Methods ◽  
Metal Species

Comparison of results for 13 clinical laboratory determinations with three automated analytical systems.

1976 ◽  
Vol 22 (3) ◽  
pp. 346-349 ◽  
Author(s):  
E J Sampson ◽  
D D Derck ◽  
L M Demers
Keyword(s):  
Normal Control ◽  
Continuous Flow ◽  
Clinical Laboratory ◽  
Clinical Chemistry ◽  
Chemistry Laboratory ◽  
Upper Limits ◽  
Control Serum ◽  
Flow Systems ◽  
Clinical Chemistry Laboratory ◽  
Better Than

Abstract We evaluated the Abbott Bichromatic Analyzer-100 (ABA-100) for use in the routine clinical chemistry laboratory by examining 13 different determinations that can be performed on the instrument. Results with the Du Pont "aca" and Technicon continuous-flow systems were compared to the ABA-100 in terms of upper limits of linearity, inter-run coefficient of variation, and results for samples from patients. The upper limits of linearity for the methods on the ABA-100 exceeded all of those for the continuous-flow systems, except for urea nitrogen. Precision of the ABA-100 was as good as or better than that of the aca for all determinations, except for glucose in a normal control serum and creatine kinase and creatinine in an above-normal control serum.

A Decade of Development in Immunoassay Methodology

1990 ◽  
Vol 36 (8) ◽  
pp. 1408-1427 ◽  
Author(s):  
James P Gosling
Keyword(s):  
Monoclonal Antibodies ◽  
Liquid Phase ◽  
Analytical Methods ◽  
Clinical Laboratory ◽  
Solid Phase ◽  
Detection Limits ◽  
Assay System ◽  
Future Trends ◽  
Homogeneous Systems ◽  
Major Trend

Abstract Immunoassays are now very widely used in the clinical laboratory, either because no other type of assay system is feasible or because they are often the most effective and suitable of the possible analytical methods. The last decade has seen the development and refinement of many new immunoassay reagents and systems. The major trend has been away from liquid-phase assays involving radioisotopic labels, towards fast homogeneous or solid-phase assays capable of operation anywhere; and towards precise and reliable nonisotopic, automated or semi-automated laboratory assays, often with detection limits measured in pico- or attomoles. The use of monoclonal antibodies is now widespread, and the methodologies of labels and of solid-phase components are much more sophisticated. New assay formulations, novel homogeneous systems, immunosensors, free-analyte assays, the importance of thorough validation and of interfering substances, and future trends are discussed.

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