The patients’ perspective on coordinated action for cancer and AMR

Abstract The speaker will present the perspective of the cancer patients, and the challenges they encounter across the spectrum of care and what measures they consider relevant in terms of prevention, diagnosis, treatment and, indeed, to raise awareness of the impact of AMR on rendering cancer treatments ineffective. She will elaborate on survivorship, and on the impact of AMR on the quality of life of patients, their carers, and families. Emphasis will be given on the implications of modern therapies, such as immunotherapy, representing a unique challenge in terms of better understanding the effect on overall health of patients, with the effect they have the immune system, further weakening the patient and leaving him/her exposed to infections potentially of higher risk than cancer itself.

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Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ quality of life: An Arabic version of the Functional Living Index-Emesis

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155221998447 ◽

2021 ◽

pp. 107815522199844

Author(s):

Abdullah M Alhammad ◽

Nora Alkhudair ◽

Rawan Alzaidi ◽

Latifa S Almosabhi ◽

Mohammad H Aljawadi

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Arabic Language ◽

Nausea And Vomiting ◽

Cancer Center ◽

Arabic Version ◽

Patient Reported ◽

Arabic Speaking ◽

The Impact

Introduction Chemotherapy-induced nausea and vomiting is a serious complication of cancer treatment that compromises patients’ quality of life and treatment adherence, which necessitates regular assessment. Therefore, there is a need to assess patient-reported nausea and vomiting using a validated scale among Arabic speaking cancer patient population. The objective of this study was to translate and validate the Functional Living Index-Emesis (FLIE) instrument in Arabic, a patient-reported outcome measure designed to assess the influence of chemotherapy-induced nausea and vomiting on patients’ quality of life. Methods Linguistic validation of an Arabic-language version was performed. The instrument was administered to cancer patients undergoing chemotherapy in a tertiary hospital's cancer center in Saudi Arabia. Results One-hundred cancer patients who received chemotherapy were enrolled. The participants’ mean age was 53.3 ± 14.9 years, and 50% were female. Half of the participants had a history of nausea and vomiting with previous chemotherapy. The Cronbach coefficient alpha for the FLIE was 0.9606 and 0.9736 for nausea and vomiting domains, respectively, which indicated an excellent reliability for the Arabic FLIE. The mean FLIE score was 110.9 ± 23.5, indicating no or minimal impact on daily life (NIDL). Conclusions The Arabic FLIE is a valid and reliable tool among the Arabic-speaking cancer population. Thus, the Arabic version of the FLIE will be a useful tool to assess the quality of life among Arabic speaking patients receiving chemotherapy. Additionally, the translated instrument will be a useful tool for future research studies to explore new antiemetic treatments among cancer patients.

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Analysis of the Impact of Personalized Nursing Service and Hospice Care on the Quality of Life of Elderly Cancer Patients

Tobacco Regulatory Science ◽

10.18001/trs.7.4.24 ◽

2021 ◽

Vol 7 (4) ◽

pp. 469-473

Author(s):

Ting Fang ◽

Nian Wang ◽

Meng Chen ◽

Hongmei Ma

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Advanced Cancer ◽

Hospice Care ◽

Pain Treatment ◽

Control Group ◽

Study Group ◽

The Difference ◽

The Impact

Objective Explore the impact of personalized nursing services and hospice care on the quality of life of elderly patients with advanced cancer. Method We selected 80 elderly cancer patients admitted to our hospital from September 2020 to May 2021, and divided these patients into a study group and a control group using a random number table method. The patients in the control group used conventional nursing methods to treat and care for the patients, and the patients in the study group used hospice care measures and combined personalized nursing measures. The quality of life and pain treatment effects of the two groups of patients before and after treatment were compared. Result Before treatment, the quality-of-life scores of the two groups of patients were low, and there was no statistical difference (P>0.05); After treatment, the quality of life of the two groups of patients improved, but compared with the control group, the improvement was more obvious in the study group, and the difference was statistically significant (P<0.05). In terms of pain treatment effect, the total effective rate of pain treatment in the study group was 87.5%, which was significantly better than the 62.5% in the control group. The difference was statistically significant (P<0.05). Conclusion Personalized nursing services and hospice care are conducive to improving the survival and treatment of elderly patients with advanced cancer, and can be used as a clinical application program for the care of advanced cancer patients.

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The impact of muscle relaxation techniques on the quality of life of cancer patients, as measured by the FACT-G questionnaire

PLoS ONE ◽

10.1371/journal.pone.0184147 ◽

2017 ◽

Vol 12 (10) ◽

pp. e0184147 ◽

Cited By ~ 10

Author(s):

Paula Parás-Bravo ◽

Paloma Salvadores-Fuentes ◽

Cristina Alonso-Blanco ◽

María Paz-Zulueta ◽

Miguel Santibañez-Margüello ◽

...

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Muscle Relaxation ◽

Relaxation Techniques ◽

The Impact

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Effect of different modalities of treatment on the quality of life of breast cancer patients in Egypt

Eastern Mediterranean Health Journal ◽

10.26719/1997.3.1.68 ◽

1997 ◽

Vol 3 (1) ◽

pp. 68-81

Author(s):

Fatma M. El Sharkawi ◽

Mahmoud F. Sakr ◽

Hoda Y. Atta ◽

Hafez M. Ghanem

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Therapy ◽

Adjuvant Therapy ◽

Cancer Patients ◽

Breast Cancer Patients ◽

Breast Cancer Therapy ◽

Egyptian Women ◽

The Impact

The impact of breast cancer therapy on the quality of life [QL] of Egyptian women was studied. Patients were divided into four groups:1:mastectomy alone;2:surgery plus radiotherapy;3:surgery plus chemotherapy;and 4:triple modality. The results revealed that all the four domains of QL of women having adjuvant therapy [groups 2, 3, or 4] were significantly altered compared to those who underwent mastectomy alone. Triple modality adversely affected global QL the most compared to radiotherapy or chemotherapy;radiotherapy had significantly less effect on QL compared to chemotherapy. Triple modality predicted the worst QL. QL measures should be incorporated with the traditional end points for evaluation of treatment and patients given health education on the effects of each therapy

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Patients’ perspective of the impact of COPD on quality of life: a focus group study for patients with COPD

International Journal of Clinical Pharmacy ◽

10.1007/s11096-018-0614-z ◽

2018 ◽

Vol 40 (3) ◽

pp. 573-579 ◽

Cited By ~ 3

Author(s):

Anan Jarab ◽

Eman Alefishat ◽

Tareq Mukattash ◽

Karem Alzoubi ◽

Sharrel Pinto

Keyword(s):

Quality Of Life ◽

Focus Group ◽

Focus Group Study ◽

The Impact ◽

Patients Perspective

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Young-onset colorectal cancer treatment side effects: Infertility, sexual dysfunction, and quality-of-life outcomes.

Journal of Clinical Oncology ◽

10.1200/jco.2021.39.15_suppl.3587 ◽

2021 ◽

Vol 39 (15_suppl) ◽

pp. 3587-3587

Author(s):

Laura Diane Porter ◽

Ronit Yarden ◽

Kim Lynn Newcomer ◽

Negeen Fathi ◽

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Side Effects ◽

Sexual Dysfunction ◽

Cancer Patients ◽

Fertility Preservation ◽

Cancer Treatments ◽

Young Onset

3587 Background: Colorectal cancer is the third-most commonly diagnosed cancer and the second-leading cause of cancer death in men and women combined in the United States. Young-onset colorectal cancer refers to individuals diagnosed under the age of 50. In recent years, the incidence has increased by 2.2% annually in individuals younger than 50 years and 1% in individuals 50-64, in contrast to a 3.3% decrease in adults 65 years and older. Young-onset (YO) CRC patients and survivors face unique clinical challenges with fertility and sexual dysfunctions, but this risk is not well quantified. There is limited data and public discussion on the long-term effects of colorectal cancer treatments on fertility and sexual dysfunction and the long-term impact on the quality of life. Methods: To explore the unique challenges and unmet needs of the young-adult patient population, a cross-sectional study was conducted. Colorectal cancer patients and survivors (N = 884) diagnosed between the ages of 20 to 50 years old (median age 42 ± 7.0) completed an online questionnaire based on established instruments EORTC-QOL-30, EORTC-CR-29, and EORTC-SHC-22. Results: Thirty-one percent of respondents stated that a medical professional spoke to them about fertility preservation at the time of diagnosis and during treatment. Only 31% were referred to a reproductive endocrinologist, even though 37% of women and 16% of men reported that treatment left them infertile or sterile. Among survey respondents, 12% of women had an egg retrieval procedure, and 36% of men had their sperm preserved prior to the start of treatment. Fifty-three percent of women reported treatment led to premature menopause. Sixty-five percent of respondents suffer from some level of sexual dysfunction due to treatment. In patients who received radiation therapy, women were 12% less likely than men to have discussed sexual side effects with the provider before treatment. Patients who have an ostomy reported more severe sexual dysfunction (17.8%). Rectal cancer patients were 2.5 times more likely than those with colon cancer to report severe dysfunction after their treatment. More than 25% of the respondents said they would have considered alternative treatment if they would have known the risks of sexual dysfunction. Conclusions: Our survey demonstrates inadequate communications between patients and providers about the irreversible fertility and sexual effects of colorectal cancer treatments. Younger patients and survivors face unique long-term challenges and require further information about fertility preservation options and emotional support regarding their sexuality post-treatment. Other studies are needed to assess the physical and psychological side effects endured by young-onset CRC patients and survivors.

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Iron deficiency after kidney transplantation

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa123 ◽

2020 ◽

Author(s):

Joanna Sophia J Vinke ◽

Marith I Francke ◽

Michele F Eisenga ◽

Dennis A Hesselink ◽

Martin H de Borst

Keyword(s):

Quality Of Life ◽

Heart Failure ◽

Immune System ◽

Iron Deficiency ◽

Patient Outcomes ◽

Excess Mortality ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

The Impact

Abstract Iron deficiency (ID) is highly prevalent in kidney transplant recipients (KTRs) and has been independently associated with an excess mortality risk in this population. Several causes lead to ID in KTRs, including inflammation, medication and an increased iron need after transplantation. Although many studies in other populations indicate a pivotal role for iron as a regulator of the immune system, little is known about the impact of ID on the immune system in KTRs. Moreover, clinical trials in patients with chronic kidney disease or heart failure have shown that correction of ID, with or without anaemia, improves exercise capacity and quality of life, and may improve survival. ID could therefore be a modifiable risk factor to improve graft and patient outcomes in KTRs; prospective studies are warranted to substantiate this hypothesis.

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Impact of Comorbidities on Quality Of Life in Breast Cancer Patients

Indian Journal of Cardiovascular Disease in Women WINCARS ◽

10.1055/s-0038-1656491 ◽

2016 ◽

Vol 01 (04) ◽

pp. 025-028

Author(s):

Monica Irukulla ◽

Rama Vaghmare ◽

Deepa Joseph ◽

Syed Ahmed ◽

Jyothi Jonnadula ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Physical Functioning ◽

Bodily Pain ◽

Evidence Base ◽

Breast Cancer Patients ◽

Co Morbidity ◽

The Impact

AbstractIntroduction: Comorbidities are common among cancer patients and with an aging population are becoming more prevalent. These can potentially affect the stage at diagnosis, treatment and outcomes of people with cancer. Despite the intimate relationship between comorbidity and cancer, there is limited consensus on how to record, interpret or manage comorbidities in the context of cancer. Addressing the impact of comorbid conditions in cancer patients warrants improvement in the evidence base from which to make treatment decisions for those with comorbidities.Methods: In this prospective study, 64 patients with breast cancer, underwent QOL assessment using FACT –B questionnaire at three time points- pre-radiation and three and six months post radiation.Results: 29(46%) patients had comorbidities of which 23 (35%) had cardiovascular comorbidities and 6 had other comorbidities. The co-morbidities were negatively associated with multiple domains of quality of life, including physical functioning, general health, bodily pain. Patients with diabetes and hypertension had significantly lower scores in physical functioning in comparison to patients without diabetes and hypertension, but improved after treatment. In majority of patients the overall scores were less in patients with co-morbidities compared to patients without any co-morbidity.Conclusion: Comorbidities can significantly affect the quality of life in patients with comorbidities. Hence greater research into the QOL issues for better patient care and symptom management especially during the transitioning phase from active care to follow up will help clinicians improve the quality of care and interdisciplinary co-ordination.

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