scholarly journals A ruptured giant mediastinal mature teratoma mimicking an encapsulated empyema

Author(s):  
Junjie Zhang ◽  
Xiaobo Zhu ◽  
Minyan Jiang ◽  
Yajun Lv

Abstract A female patient with a right-sided encapsulated pleural effusion was misdiagnosed preoperatively as having an encapsulated empyema. However, a giant mass in the anterior mediastinum was found via thoracoscopy, and a mature teratoma was detected based on the pathological result. Herein we report this case and provide lessons for cardiothoracic surgeons.

Author(s):  
João Tavares ◽  
Bernardo Baptista ◽  
Bebiana Gonçalves ◽  
Pedro Raimundo ◽  
Henrique Vaz Velho ◽  
...  

We present the case of a 22-year-old man who presented with cough, haemoptysis and fever of 3 days’ duration. A teratoma had been diagnosed 2 years previously. Physical examination was unremarkable but laboratory tests showed anaemia, neutrophilic leucocytosis and an increase in C-reactive protein. Chest CT revealed a teratoma of the anterior mediastinum with post-obstructive pneumonitis suggestive of tumour rupture. Antibiotic treatment resulted in a good clinical outcome. The patient was submitted to a left upper lobectomy and pathological examination revealed a mature teratoma. Teratomas are germ cell tumours that are usually asymptomatic and their rupture is a rare event.


2020 ◽  
pp. 014556132092556
Author(s):  
Huiyi Deng ◽  
Zhiyuan Wang ◽  
Qintai Yang ◽  
Jin Ye

There have been few reports of mature cystic teratoma, also known as a dermoid cyst, in the head and neck. Cervical neck teratoma extending into the mediastinum is also relatively rare. Here, we report a mature teratoma found in a cervical tumor in a 21-year-old man. This is the first reported case of a mature cervical teratoma extending into the anterior mediastinum. A combination of frontal X-ray, ultrasonography, computed tomography, and magnetic resonance imaging indicated a large oval heterogeneous mass surrounding the thyroid gland and trachea, underneath the sternocleidomastoid and sternohyoid, which pressed on the left lobar thyroid and trachea and extended into the anterior mediastinum. Based on preoperative observation, a diagnosis of an embryonal benign tumor was made. Although rare, this case demonstrates that these tumors should be completely removed during workup of cervical tumors.


2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Mustafa Erman Dorterler ◽  
Mehmet Emin Boleken ◽  
Sezen Koçarslan

The vast majority of teratomas originating from more than a single germ layer are benign. Often, such teratomas are initially asymptomatic. Later symptoms are caused by the weight per se of the teratoma and include chest pain, cough, dyspnea, and/or recurrent attacks of pneumonia. A mediastinal teratoma is treated by total surgical resection of the mass. Here, we report a case of giant mature cystic teratoma mimicking a pleural effusion in the thorax at the 7-month-old female patient with a symptom of persistent pulmonary infection and tachypnea.


2017 ◽  
Vol 4 ◽  
pp. 282-284
Author(s):  
Krystian Pawlak ◽  
Cezary Piwkowski ◽  
Szymon Smoliński ◽  
Wojciech Dyszkiewicz

Cureus ◽  
2021 ◽  
Author(s):  
Mubashar Iqbal ◽  
Hira Yousuf ◽  
Zara Majeed ◽  
Muhammad Zohaib ◽  
Ashish Mishra ◽  
...  

2019 ◽  
Vol 6 (11) ◽  
pp. 4177
Author(s):  
Divyang Dave ◽  
Nipun Bansal ◽  
Hardik Astik ◽  
Varun Joshi ◽  
Ojas Patel

Teratomas are the most common germ cell tumours composed of two or more germ layers. Mediastinum is the most common site of extragonadal germ cell tumour. Teratomas are relatively rare of all tumours in mediastinum. Here, we report a rare case of an adolescent who presented with chest pain and breathlessness. CT scan showed a large, well-defined lesion with internal fat density, calcifications, cystic and solid components arising from anterior mediastinum. He was successfully operated and treated at New Civil Hospital Surat attached to Government Medical College Surat. The purpose of this case report is to bring in light to the mediastinal mature teratomas in adolescents as they have very low incidence rate.


Chest Imaging ◽  
2019 ◽  
pp. 475-479
Author(s):  
Melissa L. Rosado-de-Christenson

neoplasms and lymphoma characteristically affect the anterior mediastinum while neurogenic neoplasms typically occur in the paravertebral regions. Patients with mediastinal neoplasms may be asymptomatic or may present because of symptoms of compression or local invasion. Patients with thymoma may also present with paraneoplastic syndromes including myasthenia gravis. Thymoma is the most common primary anterior mediastinal neoplasm and usually manifests as a unilateral soft tissue mass with lobular contours that may exhibit local invasion or drop pleural metastases. Mature teratoma often demonstrates a spherical morphology and cystic change; intrinsic fat attenuation in such a lesion is virtually diagnostic. Malignant germ cell neoplasms almost exclusively affect men and manifest as anterior mediastinal soft tissue masses that may be homogeneous or exhibit areas of low attenuation from central necrosis and are indistinguishable from lymphoma with nodal coalescence on imaging. Neurogenic neoplasms are paravertebral lesions that may produce skeletal erosion and intraspinal extension and are optimally evaluated with MRI. Imaging diagnosis of primary mediastinal neoplasms requires identification of a mediastinal mass, placement of the mass in a specific mediastinal compartment and characterization of the lesion with cross-sectional imaging to formulate a focused differential diagnosis and appropriate management recommendations.


Author(s):  
Tarang Patel ◽  
Swati Jindal ◽  
Ayushi Saxena ◽  
Aruna Panchariya

Introduction: Germ Cell Tumours (GCT) are heterogenous tumours believed to arise from primordial germ cells. The GCT predominantly affects gonads (testis and ovary) and also involves extragonadal sites, characteristically locations along midline of the body. The GCT of testis, ovary and extragonadal sites show peculiar histomorphological features and types subject to the age and site of patient. Definite histopathological typing of GCT is of vital importance to decide the further treatment. Till now, very few studies have been conducted in India on GCT of gonads and extragonadal sites. Aim: To study the pathologic findings of GCT including macroscopic and microscopic features and to classify the tumours according to latest World Health Organisation (WHO) classification of GCT for designated site of origin. Materials and Methods: Retrospective analysis was conducted including 141 cases of GCT of all sites, diagnosed at a tertiary cancer centre in Udaipur, Rajasthan, India between January 2016 to April 2021. Data were collected regarding demographic, clinical, gross and histopathological details. Results were analysed using Statistical Package of Social Sciences (SPSS) software Version 21.0. method. Results: Germinal cell tumours shows various age ranges for different site of origin. Ovarian GCT age varies from seven years to 65 years. Age group of testicular GCT varies from 1-55 years. Extragonadal GCT (EG GCT) was seen as early as in four-day-old newborn. Out of 141 cases, 103 were ovarian, 21 were testicular and 17 were EG GCT cases. Most common ovarian GCT is Mature Teratoma (MT) (85 cases, 82.53%) and most common malignant ovarian GCT is dysgerminoma (9 cases, 8.74%). Most common testicular GCT type is Malignant Mixed GCT (MM GCT) (9 cases, 42.86%) followed by seminoma (5 cases, 23.81%) and Yolk Sac Tumours (YST) (3 cases, 14.29%). EG GCT involves retroperitoneum (5 cases, 29.41%), anterior mediastinum (4 cases, 23.53%), Sacrococcyx (3 cases, 17.65%) and Central Nervous System (CNS) (2 cases, 11.76%) with most common EG GCT is teratoma (9 cases, 52.94%) Conclusion: Gonadal and extragonadal GCT share many common tumours, albeit, distinctive site-specific histopathological findings also present. These features often complicate the definitive diagnosis of GCT for pathologists, specifically in cases of MM GCT.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Eri Nakajima ◽  
Yujin Kudo ◽  
Sachio Maehara ◽  
Hideyuki Furumoto ◽  
Jun Matsubayashi ◽  
...  

Abstract Background Mediastinal teratomas occasionally rupture into the thoracic cavity, which induces mediastinitis or various other severe complications. Surgical treatment is crucial for ruptured teratomas; however, few literature reviews to date have addressed the characteristics of ruptured mediastinal teratomas. Case presentation We report a 29-year-old woman with severe mediastinitis owing to a mediastinal mature teratoma that ruptured into the mediastinum and right pleural cavity. Surgical resection by median sternotomy was performed within 24 hours after emergency admission. Intraoperative findings demonstrated the ruptured wall of the tumor with exposure of its white contents, which appeared similar to skin and fat, and necrotic tissue in the anterior mediastinum. The tumor was adhered to the right upper lobe, the ascending aorta, and pericardium. Owing to the severe adhesion of the tumor caused by inflammation in the surrounding tissues, a small portion of the tumor could not be removed, and hence complete resection with a sufficient surgical margin was not achieved. Pathologically, the tumor consisted of a solid mass and a cystic mass with severe adhesion to the resected portion of the lung, which included skin and lipid tissue. The tumor was concluded to be a mature teratoma as neither an immature component nor malignant transformation was observed. The patient had an uneventful postoperative course. Conclusions To our knowledge, this is the report of successful surgical resection of a ruptured mediastinal teratoma causing severe mediastinitis, with the first literature review of ruptured mediastinal teratomas. We also discuss relevant findings from reports in the literature.


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