scholarly journals Outpatient parenteral antimicrobial therapy (OPAT): is it safe for selected patients to self-administer at home? A retrospective analysis of a large cohort over 13 years

2007 ◽  
Vol 60 (2) ◽  
pp. 356-362 ◽  
Author(s):  
Philippa C. Matthews ◽  
Christopher P. Conlon ◽  
Anthony R. Berendt ◽  
Jill Kayley ◽  
Lorrayne Jefferies ◽  
...  
2018 ◽  
Vol 13 (12) ◽  
pp. 1363-1373 ◽  
Author(s):  
Pedro Sanroma ◽  
Pedro Muñoz ◽  
Manuel Mirón-Rubio ◽  
Ana Aguilera ◽  
Oriol Estrada ◽  
...  

2015 ◽  
Vol 71 (2) ◽  
pp. 506-512 ◽  
Author(s):  
Nabin K. Shrestha ◽  
Jugnu Shrestha ◽  
Angela Everett ◽  
Donald Carroll ◽  
Steven M. Gordon ◽  
...  

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S213-S214
Author(s):  
Nabin Shrestha ◽  
Jugnu Shrestha ◽  
Angela Everett ◽  
Don Carroll ◽  
Steven Gordon ◽  
...  

2016 ◽  
Vol 11 (3) ◽  
pp. 375-390 ◽  
Author(s):  
Manuel Mirón-Rubio ◽  
Víctor González-Ramallo ◽  
Oriol Estrada-Cuxart ◽  
Pedro Sanroma-Mendizábal ◽  
Antonio Segado-Soriano ◽  
...  

2017 ◽  
Vol 50 (1) ◽  
pp. 114-118 ◽  
Author(s):  
V.J. González-Ramallo ◽  
M. Mirón-Rubio ◽  
A. Mujal ◽  
O. Estrada ◽  
C. Forné ◽  
...  

2020 ◽  
Vol 7 (11) ◽  
Author(s):  
Judith Álvarez Otero ◽  
Jose Luis Lamas Ferreiro ◽  
Ana Sanjurjo Rivo ◽  
Javier de la Fuente Aguado

Abstract We present a case of Pseudomonas aeruginosa osteomyelitis treated with surgery and antibiotic therapy with ceftolozane-tazobactam in continuous infusion at home using an elastomeric pump. We discuss the use of ceftolozane-tazobactam in continuous infusion administered at home as an effective alternative for the treatment of multidrug-resistant Pseudomonas aeruginosa osteomyelitis.


BMJ Open ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. e019099 ◽  
Author(s):  
Maureen Twiddy ◽  
Carolyn J Czoski Murray ◽  
Samantha J Mason ◽  
David Meads ◽  
Judy M Wright ◽  
...  

ObjectiveOutpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation is patchy and a variety of service models are in use. The slow uptake in the UK and Europe is due to a number of clinical, financial and logistical issues, including concern about patient safety. The measurement of patient experience data is commonly used to inform commissioning decisions, but these focus on functional aspects of services and fail to examine the relational aspects of care. This qualitative study examines patients’ experiences of OPAT.DesignIn-depth, semistructured interviews.SettingPurposive sample of OPAT patients recruited from four acute National Health Service (NHS) Trusts in Northern England. These NHS Trusts between them represented both well-established and recently set-up services running nurse at home, hospital outpatient and/or self-administration models.ParticipantsWe undertook 28 semistructured interviews and one focus group (n=4).ResultsDespite good patient outcomes, experiences were coloured by patients' personal situation and material circumstances. Many found looking after themselves at home more difficult than they expected, while others continued to work despite their infection. Expensive car parking, late running services and the inconvenience of waiting in for the nurse to arrive frustrated patients, while efficient services, staffed by nurses with the specialist skills needed to manage intravenous treatment had the opposite effect. Many patients felt a local, general practitioner or community health centre based service would resolve many of the practical difficulties that made OPAT inconvenient. Patients could find OPAT anxiety provoking but this could be ameliorated by staff taking the time to reassure patients and provide tailored information.ConclusionServices configurations must accommodate the diversity of the local population. Poor communication can leave patients lacking the confidence needed to be a competent collaborator in their own care and affect their perceptions of the service.


2019 ◽  
Vol 105 (3) ◽  
pp. 276-281
Author(s):  
Bernie Carter ◽  
Debra Fisher-Smith ◽  
David Porter ◽  
Steven Lane ◽  
Matthew Peak ◽  
...  

ObjectiveTo better understand the factors that facilitate and hinder a positive experience of paediatric outpatient parenteral antimicrobial therapy (OPAT).DesignQualitative study using semistructured interviews.SettingA dedicated paediatric consultant-led hospital-based, outreach OPAT service in England.ParticipantsParticipants were primarily parents of children who had received OPAT; one child participated.MethodsChildren and parents of children who received OPAT and who had participated in the survey phase of the larger study were invited to be interviewed.Results12 parents (10 mothers and 2 fathers) of 10 children participated; one child (aged 15 years). Data analysis resulted in one meta-theme, ‘At-homeness’ with OPAT, this reflected the overall sense of home being a place in which the children and their parents could be where they wanted to be. Four key themes were identified that reflect the ways in which parents and children experienced being at-home on OPAT: ‘Comfort, security, freedom, and control’; ‘Faith, trust and confidence’; ‘Explanations and communication’ and ‘Concerns, restrictions and inconveniences’.ConclusionsDespite feeling anxious at times, parents reported that they and their children generally had a positive experience of OPAT; being at-home brought many benefits compared with in-patient care. Recommendations arising from the study include a ‘whole-system’ approach to discharge home that includes support related to return to school/nursery, reduction in disruptions to home-based routines, more clarity on choice and preparation for managing potential anxiety, better consideration of dose timing and enhanced preparation and information.


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