scholarly journals Erratum to: Mortality attributable to third-generation cephalosporin resistance in Gram-negative bloodstream infections in African hospitals: a multi-site retrospective study

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Angela Dramowski ◽  
Gerald Ong’ayo ◽  
Andrea M Rehman ◽  
Andrew Whitelaw ◽  
Appiah-Korang Labi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Bloodstream Infections ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
Gram Negative ◽  
Cephalosporin Resistance

scholarly journals Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada

1995 ◽  
Vol 6 (2) ◽  
pp. 76-82 ◽  
Author(s):  
Shelley R Scriver ◽  
Canadian Antimicrobial Resistance Study Group ◽  
Donald E Low
Keyword(s):  
Antimicrobial Agents ◽  
Wide Spectrum ◽  
Generation Cephalosporin ◽  
Third Generation ◽  
Beta Lactamase ◽  
Gram Negative ◽  
The Third ◽  
Cephalosporin Resistance ◽  
Third Generation Cephalosporins ◽  
Group 1

In 1992, a surveillance study was performed in Canada to determine the susceptibility of nosocomial Gram-negative rods to several wide spectrum antimicrobials. Consecutive isolates from 10 institutions, as well as additional strains of selected species of Enterobacteriaceae that are known to possess the Bush group 1 beta-lactamase, were tested for susceptibility to 12 antimicrobials. Third-generation cephalosporin resistance was found to be as high as 29% inEnterobacter cloacaethat possesses the Bush group 1 beta-lactamase and less than 4% in those isolates not possessing this enzyme. Cefepime equalled or exceeded the activity of the third-generation cephalosporins against the species of Enterobacteriaceae that demonstrated resistance to the third-generation cephalosporins.

scholarly journals Increasing incidence and antimicrobial resistance in Escherichia coli bloodstream infections: a multinational population-based cohort study

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Melissa C. MacKinnon ◽  
Scott A. McEwen ◽  
David L. Pearl ◽  
Outi Lyytikäinen ◽  
Gunnar Jacobsson ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Incidence Rate ◽  
Bloodstream Infections ◽  
Generation Cephalosporin ◽  
Population Based ◽  
Incidence Rates ◽  
Third Generation ◽  
Common Cause ◽  
E Coli ◽  
Cephalosporin Resistance

Abstract Background Escherichia coli is an important pathogen in humans and is the most common cause of bacterial bloodstream infections (BSIs). The objectives of our study were to determine factors associated with E. coli BSI incidence rate and third-generation cephalosporin resistance in a multinational population-based cohort. Methods We included all incident E. coli BSIs (2014–2018) from national (Finland) and regional (Australia [Canberra], Sweden [Skaraborg], and Canada [Calgary, Sherbrooke, and western interior]) surveillance. Incidence rates were directly age and sex standardized to the European Union 28-country 2018 population. Multivariable negative binomial and logistic regression models estimated factors significantly associated with E. coli BSI incidence rate and third-generation cephalosporin resistance, respectively. The explanatory variables considered for inclusion in both models were year (2014–2018), region (six areas), age (< 70-years-old and ≥ 70-years-old), and sex (female and male). Results We identified 31,889 E. coli BSIs from 40.7 million person-years of surveillance. Overall and third-generation cephalosporin-resistant standardized rates were 87.1 and 6.6 cases/100,000 person-years, respectively, and increased 14.0% and 40.1% over the five-year study. Overall, 7.8% (2483/31889) of E. coli BSIs were third-generation cephalosporin-resistant. Calgary, Canberra, Sherbrooke, and western interior had significantly lower E. coli BSI rates compared to Finland. The significant association between age and E. coli BSI rate varied with sex. Calgary, Canberra, and western interior had significantly greater odds of third-generation cephalosporin-resistant E. coli BSIs compared to Finland. Compared to 2014, the odds of third-generation cephalosporin-resistant E. coli BSIs were significantly increased in 2016, 2017, and 2018. The significant association between age and the odds of having a third-generation cephalosporin-resistant E. coli BSI varied with sex. Conclusions Increases in overall and third-generation cephalosporin-resistant standardized E. coli BSI rates were clinically important. Overall, E. coli BSI incidence rates were 40–104% greater than previous investigations from the same study areas. Region, sex, and age are important variables when analyzing E. coli BSI rates and third-generation cephalosporin resistance in E. coli BSIs. Considering E. coli is the most common cause of BSIs, this increasing burden and evolving third-generation cephalosporin resistance will have an important impact on human health, especially in aging populations.

Prevalence and Predictors of Third-Generation Cephalosporin Resistance in the Empirical Treatment of Spontaneous Bacterial Peritonitis

2019 ◽  
Vol 94 (8) ◽  
pp. 1499-1508 ◽  
Author(s):  
Dharma B. Sunjaya ◽  
Ryan J. Lennon ◽  
Vijay H. Shah ◽  
Patrick S. Kamath ◽  
Douglas A. Simonetto
Keyword(s):  
Spontaneous Bacterial Peritonitis ◽  
Generation Cephalosporin ◽  
Empirical Treatment ◽  
Third Generation ◽  
Bacterial Peritonitis ◽  
Cephalosporin Resistance

scholarly journals Superbugs in the supermarket? Assessing the rate of contamination with third-generation cephalosporin-resistant gram-negative bacteria in fresh Australian pork and chicken

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Jade E. McLellan ◽  
Joshua I. Pitcher ◽  
Susan A. Ballard ◽  
Elizabeth A. Grabsch ◽  
Jan M. Bell ◽  
...  
Keyword(s):  
Generation Cephalosporin ◽  
Gram Negative Bacteria ◽  
Third Generation ◽  
Gram Negative

Gram-negative bloodstream infections in hemodialysis patients: A retrospective study

2018 ◽  
Vol 90 (2) ◽  
pp. 117-124
Author(s):  
Orit Shimon ◽  
Hefziba Green ◽  
Noa Eliakim-Raz ◽  
Benaya Rozen-Zvi ◽  
Haim Ben-Zvi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Bloodstream Infections ◽  
Hemodialysis Patients ◽  
Gram Negative

Characterization of Third-Generation Cephalosporin-ResistantEscherichia colifrom Bloodstream Infections in Denmark

2014 ◽  
Vol 20 (4) ◽  
pp. 316-324 ◽  
Author(s):  
Frank Hansen ◽  
Stefan S. Olsen ◽  
Ole Heltberg ◽  
Ulrik S. Justesen ◽  
David Fuglsang-Damgaard ◽  
...  
Keyword(s):  
Bloodstream Infections ◽  
Generation Cephalosporin ◽  
Third Generation

scholarly journals Third-Generation Cephalosporin Resistance inShigella sonnei, Argentina

2001 ◽  
Vol 7 (3) ◽  
pp. 442-443 ◽  
Author(s):  
Marcela Radice ◽  
Cristina González ◽  
Pablo Power ◽  
María del Carmen Vidal ◽  
Gabriel Gutkind
Keyword(s):  
Generation Cephalosporin ◽  
Third Generation ◽  
Cephalosporin Resistance
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