Short-Term Fluctuations and Long-Term Trends in Anchorage-Independent Multiplication Among Cryopreserved Subpopulations of a Spontaneously Transformed Balb/3T3 Clone2

Keyword(s):  
1984 ◽  
Vol 1 (19) ◽  
pp. 112 ◽  
Author(s):  
Jennifer E. Dick ◽  
Robert A. Dalrymple

The coastal processes affecting Bethany Beach, Delaware were studied and the short-term and long-term trends in coastal changes were determined in order to develop recommendations for protecting Bethany against coastal erosion (Dick and Dalrymple, 1983). Bethany Beach is located on the Delaware Atlantic coastline which is a wide sandy baymouth barrier beach distinguished by highlands at Rehoboth Beach and Bethany Beach. The shoreline is straight, with only minor bulges and indentations (see Figure 1). Bethany Beach is a residential and resort community. Privatelyowned properties front the publicly-owned beach. Construction of new motels and summer homes is anticipated along with the continued growth of commercial activities to accommodate the increased number of visitors. Bethany is protected by a series of nine groins built between 1934 and 1945. Many of these groins have deteriorated, and are flanked at the landward end. Winter storms severely erode the beach and damage shorefront property. The beach is generally narrow (approximately 45 m wide), especially along the southern portion, and is backed by low dunes (about 15-45 m above NGVD). A timber bulkhead extends along most of the backshore.


2020 ◽  
pp. 336-362
Author(s):  
Peter Ferdinand

This chapter focuses on democracies, democratization, and authoritarian regimes. It first considers the two main approaches to analysing the global rise of democracy over the last thirty years: first, long-term trends of modernization, and more specifically economic development, that create preconditions for democracy and opportunities for democratic entrepreneurs; and second, the sequences of more short-term events and actions of key actors at moments of national crisis that have precipitated a democratic transition — also known as ‘transitology’. The chapter proceeds by discussing the different types of democracy and the strategies used to measure democracy. It also reviews the more recent literature on authoritarian systems and why they persist. Finally, it examines the challenges that confront democracy in the face of authoritarian revival.


2018 ◽  
Vol 18 (21) ◽  
pp. 16121-16137 ◽  
Author(s):  
Jihoon Seo ◽  
Doo-Sun R. Park ◽  
Jin Young Kim ◽  
Daeok Youn ◽  
Yong Bin Lim ◽  
...  

Abstract. Together with emissions of air pollutants and precursors, meteorological conditions play important roles in local air quality through accumulation or ventilation, regional transport, and atmospheric chemistry. In this study, we extensively investigated multi-timescale meteorological effects on the urban air pollution using the long-term measurements data of PM10, SO2, NO2, CO, and O3 and meteorological variables over the period of 1999–2016 in Seoul, South Korea. The long-term air quality data were decomposed into trend-free short-term components and long-term trends by the Kolmogorov–Zurbenko filter, and the effects of meteorology and emissions were quantitatively isolated using a multiple linear regression with meteorological variables. In terms of short-term variability, intercorrelations among the pollutants and meteorological variables and composite analysis of synoptic meteorological fields exhibited that the warm and stagnant conditions in the migratory high-pressure system are related to the high PM10 and primary pollutant, while the strong irradiance and low NO2 by high winds at the rear of a cyclone are related to the high O3. In terms of long-term trends, decrease in PM10 (−1.75 µg m−3 yr−1) and increase in O3 (+0.88 ppb yr−1) in Seoul were largely contributed by the meteorology-related trends (−0.94 µg m−3 yr−1 for PM10 and +0.47 ppb yr−1 for O3), which were attributable to the subregional-scale wind speed increase. Comparisons with estimated local emissions and socioeconomic indices like gross domestic product (GDP) growth and fuel consumptions indicate probable influences of the 2008 global economic recession as well as the enforced regulations from the mid-2000s on the emission-related trends of PM10 and other primary pollutants. Change rates of local emissions and the transport term of long-term components calculated by the tracer continuity equation revealed a decrease in contributions of local emissions to the primary pollutants including PM10 and an increase in contributions of local secondary productions to O3. The present results not only reveal an important role of synoptic meteorological conditions on the episodic air pollution events but also give insights into the practical effects of environmental policies and regulations on the long-term air pollution trends. As a complementary approach to the chemical transport modeling, this study will provide a scientific background for developing and improving effective air quality management strategy in Seoul and its metropolitan area.


Author(s):  
Simone Amendola ◽  
Martin Plöderl ◽  
Michael P Hengartner

Abstract Background Ecological studies have explored associations between suicide rates and antidepressant prescriptions in the population, but most of them are limited as they analyzed short-term correlations that may be spurious. The aim of this long-term study was to examine whether trends in suicide rates changed in three European countries when the first antidepressants were introduced in 1960 and when prescription rates increased steeply after 1990 with the introduction of the serotonin reuptake inhibitors (SSRIs). Methods Data were extracted from the WHO Mortality Database. Suicide rates were calculated for people aged 10–89 years from 1951–2015 for Italy, 1955–2016 for Austria and 1951–2013 for Switzerland. Trends in suicide rates stratified by gender were analyzed using joinpoint regression models. Results There was a general pattern of long-term trends that was broadly consistent across all three countries. Suicide rates were stable or decreasing during the 1950s and 1960s, they rose during the 1970s, peaked in the early 1980s and thereafter they declined. There were a few notable exceptions to these general trends. In Italian men, suicide rates increased until 1997, then fell sharply until 2006 and increased again from 2006 to 2015. In women from all three countries, there was an extended period during the 2000s when suicide rates were stable. No trend changes occurred around 1960 or 1990. Conclusions The introduction of antidepressants around 1960 and the sharp increase in prescriptions after 1990 with the introduction of the SSRIs did not coincide with trend changes in suicide rates in Italy, Austria or Switzerland.


2019 ◽  
Author(s):  
Eirini Boleti ◽  
Christoph Hueglin ◽  
Stuart K. Grange ◽  
André S. H. Prévôt ◽  
Satoshi Takahama

Abstract. Air quality measures that were implemented in Europe in the 1990s resulted in reductions of ozone precursors concentrations. In this study, the effect of these reductions on ozone is investigated by analyzing surface measurements of ozone for the time period between 2000 and 2015. Using a non-parametric time scale decomposition methodology, the long-term, seasonal and short-term variation of ozone observations were extracted. A clustering algorithm was applied to the different time scale variations, leading to a classification of sites across Europe based on the temporal characteristics of ozone. The clustering based on the long-term variation resulted in a site type classification, while a regional classification was obtained based on the seasonal and short-term variations. Long-term trends of de-seasonalized mean and meteo-adjusted peak ozone concentrations were calculated across large parts of Europe for the time period 2000–2015. A multi-dimensional scheme was used for a detailed trend analysis, based on the identified clusters, which reflect precursor emissions and meteorological influence either on the inter-annual or the short-term time scale. Decreasing mean ozone concentrations at rural sites and increasing or stabilizing at urban sites were observed. At the same time downward trends for peak ozone concentrations were detected for all site types. The effect of hemispheric transport of ozone can be seen either in regions affected by synoptic patterns in the northern Atlantic or at sites located at remote high altitude locations. In addition, a reduction of the amplitude in the seasonal cycle of ozone was observed, and a shift in the occurrence of the seasonal maximum towards earlier time of the year. Finally, a reduced sensitivity of ozone to temperature was identified. It was concluded that long-term trends of mean and peak ozone concentrations are mostly controlled by precursors emissions changes, while seasonal cycle trends and changes in the sensitivity of ozone to temperature are driven by regional climatic conditions.


2015 ◽  
Vol 8 ◽  
pp. 73-77
Author(s):  
Piia Jallinoja ◽  
Nina Kahma ◽  
Satu Helakorpi ◽  
Mari Niva ◽  
Mikko Jauho

Dietary fat has long been a target of several Finnish policy sectors with conflicting interests. Changes in fat use from animal to vegetable fats have often been characterized as “a public policy success story”, in which policy interventions have led to healthier diets. The aim of this paper is to elaborate the picture of the developments in the consumption of different fat products, and to explore whether and what kind of other developments there may have been besides the general change from animal to vegetable fats. Based on population statistics between 1978 and 2014, the study shows that instead of a uniform transformation from animal to vegetable fats, there have been multiple developments simultaneously, and not all of them unambiguously agree with the "success story" discourse. The changes were related to novel fat products, health policy interventions, cultural trends, public debates on dietary fats, and fad diets.


This introduction explains how the Labour Party’s current difficulties have made a number of concerns that seemed outmoded topical again and have rekindled the interest of both academics and practitioners in organisational matters. It shows that there is a need to put present troubles into historical perspective, to demonstrate that the present disunities are nothing new, and that they are far from capturing every source of disagreement within the British labour movement, which was, from its inception, never a homogeneous entity, and was formed of different groups trying to achieve different things. This does not imply that those different components did not seek to achieve some form of unity, since for practical reasons it was often felt that divergences over long term objectives should not be an obstacle to united action around short term goals. In order to better bring out these long-term trends, the book follows a diachronic approach, from the 1830s to the present day, progressively zooming on the dilemmas experienced by the contemporary Labour Party.


10 Be is produced in a similar way as 14 C by the interaction of cosmic radiation with the nuclei in the atmosphere. Assuming that the 10 Be and 14 C variation are proportional and considering the different behaviour in the Earth system, the 10 Be concentrations in ice cores can be compared with the 14 C variations in tree rings. A high correlation is found for the short-term variations ( 14 C-Suess-wiggles). They reflect with a high probability production rate variations. More problematic is the interpretation of the long-term trends of 14 C and 10 Be. Several explanations are discussed. The reconstructed CO 2 concentrations in ice cores indicate a rather constant value (280 ± 10 p.p.m. by volume) during the past few millenia. Measurements on the ice core from Byrd Station, Antarctica, during the period 9000 to 6000 years BP indicate a decrease that might be explained by the extraction of CO 2 from the atmosphere-ocean system to build the terrestrial biomass pool during the climatic optimum.


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