scholarly journals Patient organ doses from megavoltage computed tomography delivery with a helical tomotherapy unit using a general treatment planning system

2019 ◽  
Vol 60 (3) ◽  
pp. 401-411
Author(s):  
Hironori Nagata ◽  
Satoru Sugimoto ◽  
Hideyuki Hongo ◽  
Harumitsu Hashimoto ◽  
Yuki Sato ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Treatment Planning ◽  
Helical Tomotherapy ◽  
General Treatment ◽  
Planning System ◽  
Treatment Planning System ◽  
Organ Doses ◽  
Megavoltage Computed Tomography ◽  
Patient Organ

scholarly journals Application of treatment planning system assisted large-aperture computed tomography simulator in percutaneous biopsy: initial experience by a radiation therapist

2020 ◽  
Author(s):  
Xiaoyi Lin ◽  
Jun-qiang Hong ◽  
Shui-ying Luo ◽  
You-qun Lai ◽  
Yong-liang Dai ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Success Rate ◽  
Treatment Planning ◽  
Percutaneous Biopsy ◽  
Lymph Node Biopsy ◽  
Planning System ◽  
Treatment Planning System ◽  
Initial Experience ◽  
Ct Guided ◽  
Large Aperture

Abstract Background and purpose To evaluate the application of treatment planning system (TPS) assisted large-aperture computed tomography (CT) simulator in percutaneous biopsy, and report our initial experience of the accuracy and safety of this procedure.Methods From November 2018 to December 2019, treatment planning system assisted large-aperture CT simulator guided percutaneous biopsy was performed on 38 cases, with 34 of percutaneous lung biopsy, three of abdominal lesions biopsy, and one case of deep supraclavicular lymph node biopsy. The major results including planned and actual puncture parameters, the success rate, pathological information and complications were recorded. The analyses of puncture accuracy were accomplished by pared-t test and Wilcoxon rank sum test. And the risk factors of puncture accuracy and complications were further identified.Results The entire cohort achieved one-time success of biopsy. No significant differences were presented between planned and actual puncture depth and direction (P = 0.436 and 0.382), indicating the precision of the process. And the pulmonary puncture location was related to the accuracy of puncture direction (P = 0.033). Biopsy specimens were successfully obtained in 38 cases. The diagnostic rate of malignancy was 76%, of which 80% for initial treatment group and 69% for treated group, respectively. For patients with pulmonary biopsy, 12 had minor pneumothorax and 2 progressed to massive pneumothorax. Only three cases suffered needle track bleeding, and no other complications were observed. Additionally, the regression analysis found a significant correlation between puncture angle and the incidence of pneumothorax (P = 0.027).Conclusions TPS assisted large-aperture CT simulator improved the procedure of percutaneous biopsy by combining the advantages of radiotherapy specialty. The initial results suggested the increase of puncture accuracy and success rate, with satisfactory safety simultaneously. It might offer new insights into the field of CT-guided percutaneous biopsy.

scholarly journals Initial Validation of Proton Dose Calculations on SPR Images from DECT in Treatment Planning System

2020 ◽  
Vol 7 (2) ◽  
pp. 51-61
Author(s):  
Sina Mossahebi ◽  
Pouya Sabouri ◽  
Haijian Chen ◽  
Michelle Mundis ◽  
Matthew O'Neil ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Treatment Planning ◽  
Effective Atomic Number ◽  
Dose Calculation ◽  
Target Volume ◽  
Planning System ◽  
Treatment Planning System ◽  
Relative Electron ◽  
Treatment Plans ◽  
Proton Dose

Abstract Purpose To investigate and quantify the potential benefits associated with the use of stopping-power-ratio (SPR) images created from dual-energy computed tomography (DECT) images for proton dose calculation in a clinical proton treatment planning system (TPS). Materials and Methods The DECT and single-energy computed tomography (SECT) scans obtained for 26 plastic tissue surrogate plugs were placed individually in a tissue-equivalent plastic phantom. Relative-electron density (ρe) and effective atomic number (Zeff) images were reconstructed from the DECT scans and used to create an SPR image set for each plug. Next, the SPR for each plug was measured in a clinical proton beam for comparison of the calculated values in the SPR images. The SPR images and SECTs were then imported into a clinical TPS, and treatment plans were developed consisting of a single field delivering a 10 × 10 × 10-cm3 spread-out Bragg peak to a clinical target volume that contained the plugs. To verify the accuracy of the TPS dose calculated from the SPR images and SECTs, treatment plans were delivered to the phantom containing each plug, and comparisons of point-dose measurements and 2-dimensional γ-analysis were performed. Results For all 26 plugs considered in this study, SPR values for each plug from the SPR images were within 2% agreement with measurements. Additionally, treatment plans developed with the SPR images agreed with the measured point dose to within 2%, whereas a 3% agreement was observed for SECT-based plans. γ-Index pass rates were > 90% for all SECT plans and > 97% for all SPR image–based plans. Conclusion Treatment plans created in a TPS with SPR images obtained from DECT scans are accurate to within guidelines set for validation of clinical treatment plans at our center. The calculated doses from the SPR image–based treatment plans showed better agreement to measured doses than identical plans created with standard SECT scans.

Independent calculation of dose distributions for helical tomotherapy using a conventional treatment planning system

2014 ◽  
Vol 41 (8Part1) ◽  
pp. 081709 ◽  
Author(s):  
Sebastian Klüter ◽  
Kai Schubert ◽  
Steffen Lissner ◽  
Florian Sterzing ◽  
Dieter Oetzel ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Conventional Treatment ◽  
Helical Tomotherapy ◽  
Planning System ◽  
Treatment Planning System ◽  
Dose Distributions ◽  
Independent Calculation

scholarly journals Conversion of helical tomotherapy plans to step-and-shoot IMRT plans-Pareto front evaluation of plans from a new treatment planning system

2011 ◽  
Vol 38 (6Part1) ◽  
pp. 3130-3138 ◽  
Author(s):  
Kristoffer Petersson ◽  
Crister Ceberg ◽  
Per Engström ◽  
Hunor Benedek ◽  
Per Nilsson ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Pareto Front ◽  
Helical Tomotherapy ◽  
Planning System ◽  
Treatment Planning System ◽  
Step And Shoot ◽  
New Treatment

scholarly journals Dual-Energy Computed Tomography Proton-Dose Calculation with Scripting and Modified Hounsfield Units

2021 ◽  
Vol 8 (1) ◽  
pp. 62-72
Author(s):  
Anthony Kassaee ◽  
Chingyun Cheng ◽  
Lingshu Yin ◽  
Wei Zou ◽  
Taoran Li ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Treatment Planning ◽  
Dose Calculation ◽  
Application Programming Interface ◽  
Dual Energy ◽  
Planning System ◽  
Treatment Planning System ◽  
Application Programming ◽  
Programming Interface ◽  
Proton Dose

Abstract Purpose To describe an implementation of dual-energy computed tomography (DECT) for calculation of proton stopping-power ratios (SPRs) in a commercial treatment-planning system. The process for validation and the workflow for safe deployment of DECT is described, using single-energy computed tomography (SECT) as a safety check for DECT dose calculation. Materials and Methods The DECT images were acquired at 80 kVp and 140 kVp and were processed with computed tomography scanner software to derive the electron density and effective atomic number images. Reference SPRs of tissue-equivalent plugs from Gammex (Middleton, Wisconsin) and CIRS (Computerized Imaging Reference Systems, Norfolk, Virginia) electron density phantoms were used for validation and comparison of SECT versus DECT calculated through the Eclipse treatment planning system (Varian Medical Systems, Palo Alto, California) application programming interface scripting tool. An in-house software was also used to create DECT SPR computed tomography images for comparison with the script output. In the workflow, using the Eclipse system application programming interface script, clinical plans were optimized with the SECT image set and then forward-calculated with the DECT SPR for the final dose distribution. In a second workflow, the plans were optimized using DECT SPR with reduced range-uncertainty margins. Results For the Gammex phantom, the root mean square error in SPR was 1.08% for DECT versus 2.29% for SECT for 10 tissue-surrogates, excluding the lung. For the CIRS Phantom, the corresponding results were 0.74% and 2.27%. When evaluating the head and neck plan, DECT optimization with 2% range-uncertainty margins achieved a small reduction in organ-at-risk doses compared with that of SECT plans with 3.5% range-uncertainty margins. For the liver case, DECT was used to identify and correct the lipiodol SPR in the SECT plan. Conclusion It is feasible to use DECT for proton-dose calculation in a commercial treatment planning system in a safe manner. The range margins can be reduced to 2% in some sites, including the head and neck.

SU-E-J-03: The Modeling of Cone Beam Computed Tomography in a Treatment Planning System

2011 ◽  
Vol 38 (6Part7) ◽  
pp. 3442-3442
Author(s):  
H Alkhatib ◽  
J Stenbeck ◽  
D Tedeschi ◽  
B Tsang ◽  
S Oves ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Treatment Planning ◽  
Cone Beam Computed Tomography ◽  
Planning System ◽  
Treatment Planning System ◽  
Cone Beam
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