Conclusion

Diagnosis ◽  
2021 ◽  
pp. 125-126
Author(s):  
Ashley Graham Kennedy

This concluding chapter reiterates the point that being a good diagnostician requires not only an understanding of probability theory and statistical analysis but also learning to listen to your patients, learning how to interpret the results of diagnostic tests by taking into account clinical considerations, learning how to manage and communicate diagnostic uncertainty in the clinical setting, understanding the potential reasons to conduct diagnostic tests or not, and being concerned with issues of diagnostic justice while keeping in mind the concerns of the actual patient who is in front of you.

2009 ◽  
Vol 55 ◽  
pp. 121-138
Author(s):  
John Kingman

David Kendall was the father of modern probability theory in Britain, a powerful and scholarly mathematician equally at home in abstract theory and in perceptive applications to diverse fields. Through his own research, his influence on generations of students, and from 1962 his leadership of the Cambridge Statistical Laboratory, he inspired the parallel developments of stochastic analysis and applied probability, as well as the statistical analysis of complex structured data.


PMLA ◽  
2015 ◽  
Vol 130 (1) ◽  
pp. 129-142 ◽  
Author(s):  
M. L. Gasparov ◽  
Michael Wachtel

Mikhail Leonovich Gasparov (1935-2005) was one of the greatest and most prolific russian literary scholars of the twentieth century.Though associated with the Moscow-Tartu school of semiotics, Gasparov's writings were so diverse and multifaceted—and his scholarly personality so distinct—as to elude categorization.Gasparov's accomplishments are all the more remarkable when measured against the rigid Marxist-Leninist paradigms that ruled humanities education and scholarship in the Soviet Union. A philologist with a special interest in verse form, he managed to sidestep the procrustean bed of Soviet ideology, building instead on the barely tolerated work of the Russian formalists and structuralists. He embraced and developed their goal of turning literary study into an exact science by applying statistical analysis and probability theory to poetics. Gasparov's scholarship was based on unprecedented amounts of data, which he painstakingly compiled in the precomputer era. However, he was never satisfied with the data as such; he used them to reach profound and unexpected conclusions.


2015 ◽  
Vol 110 (4) ◽  
pp. 510-516 ◽  
Author(s):  
Lyda Osorio ◽  
Marcela Uribe ◽  
Gloria Ines Ardila ◽  
Yaneth Orejuela ◽  
Margarita Velasco ◽  
...  

Scoliosis ◽  
2012 ◽  
Vol 7 (S1) ◽  
Author(s):  
AG Aulisa ◽  
V Guzzanti ◽  
G Mastantuoni ◽  
M Giordano ◽  
A Poggiaroni ◽  
...  

Author(s):  
Usha Adiga ◽  
Tirthal Rai

Objective: The objective of the study is to compare three techniques, routinely used rapid diagnostic tests (lateral flow immune chromatography) versus nucleic acid amplification test (NAT)  versus Paper-based microfluidics for DNA diagnostics of Malaria, in terms of their sensitivity and specificity as diagnostic tests in detecting malarial infection among febrile illnesses, suspected of malaria, as well as to compare their cost-effectiveness. Methodology: Three seventy febrile cases suspected of malaria with negative results with RDT will be screened by real-time PCR and DNA microfluidics techniques, sensitivity and specificity of these as screening tests will be compared. The number of extra positive cases detected by NAT gives us the yield. Cost-effectiveness analysis will be done by calculating the incremental cost-effectiveness ratio (ICER) and average cost-effectiveness ratio (ACER) for the tests. Statistical Analysis: Statistical analysis will be done using SPSS version 21. Sensitivity, specificity, Positive predictive values will be computed. Comparison of sensitivity and specificity of NAT, a paper microfluidic technique for DNA diagnostics and RDT will be carried out using McNemar’s test. Receiver operating curves will be generated separately to assess the utility of the NAT. Conclusion: The Implications of this study from the patient's perspective would mean early diagnosis which forms the tenet of control of the disease by increasing the yield. Early diagnosis at the community level would translate into the application of efficient prevention mechanisms to spread the infection. The cost-effectiveness analysis would provide a scientific basis for the adoption of the best test for the diagnosis, given the economic feasibility of the study.


Diagnosis ◽  
2021 ◽  
pp. 6-23
Author(s):  
Ashley Graham Kennedy

This chapter demonstrates how the process of clinical diagnosis requires first establishing a therapeutic alliance between the patient and the physician and then drawing on, and evaluating, both qualitative and quantitative forms of evidence. Although clinical diagnosis is a technical process that requires an understanding of scientific study design, probability theory, and statistical analysis, it is also relational because it starts with the relationship between the patient and the physician. In fact, very often, getting to a correct diagnosis directly depends on the way in which the physician navigates this relationship: If a physician is dismissive of the patient’s concerns, the physician risks cutting the patient off too quickly and possibly missing important pieces of evidence that could lead to a timely and accurate diagnosis.


2012 ◽  
Vol 23 (7) ◽  
pp. 781-784 ◽  
Author(s):  
A. G. Aulisa ◽  
V. Guzzanti ◽  
M. Galli ◽  
G. Bottaro ◽  
O. Vitelli ◽  
...  

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