Stress Testing in Children

2018 ◽  
pp. 517-532
Author(s):  
Brandy Hattendorf

The chapter Stress Testing in Children reviews the opportunity to evaluate children with congenital and acquired cardiovascular disease. Clinical pediatric exercise testing differs from adult testing in both disease etiology as well as the characteristics of cardiovascular response. Unlike exercise testing in adults, the indications for testing in pediatrics generally are not to evaluate for ischemia. Commonly, pediatric exercise testing is used to evaluate specific signs and symptoms induced or aggravated by exercise, including identification of exercise induced arrhythmias, whereas metabolic testing can provide further patient information regarding cardiac output, maximal oxygen consumption, and lung capacity. Exercise testing can also assess the efficacy of medical or surgical treatments for individual congenital heart disease patients. Functional capacity can be used to determine patient safety for recreational, athletic, and vocational activities. Exercise modification and restrictions are necessary for some patients based on the data provided by exercise testing.

1990 ◽  
Vol 2 (3) ◽  
pp. 230-248
Author(s):  
Steven R. Neish ◽  
Richard A. Friedman ◽  
J. Timothy Bricker

Exercise testing has become an important method for evaluation of pediatric patients with known or suspected arrhythmias. It has proven useful in patients with exercise-induced symptoms, patients with congenital heart disease, and patients with pacemakers. Exercise has predictable effects on the normal electrocardiogram. Exercise can also bring out abnormalities in cardiac rhythm that may not be present at rest. The results of exercise testing can provide information that directs further therapy or evaluation. Exercise testing also helps to evaluate the efficacy of antiarrhythmic therapy in some patients.


Author(s):  
Marco Guazzi ◽  
Paolo Emilio Adami

Exercise and cardiopulmonary exercise testing are essential in the evaluation of the cardiovascular response to exercise. They are clinically used to evaluate the subject’s capacity to tolerate increasing work loads. Throughout the tests electrocardiographic, haemodynamic, and symptomatic responses are monitored to assess ischaemic, hypertensive, and arrhythmic manifestations of disease. Ventilatory expired gas analysis may also be performed, as it provides fundamental information, particularly in patients with congestive heart failure or other exercise-induced limitations.


The 6th edition of the textbook Ellestad’s Stress Testing: Principles and Practice was written for the new and veteran clinician alike performing stress testing. Thoroughly updated, referenced and interspersed with case examples, the book reviews how to get the most out exercise testing, without and with ancillary imaging. In addition to evaluation of ST segment depression, other powerful tools to detect ischemia and forecast the future are reviewed to increase the diagnostic accuracy and prognostic ability of exercise testing. The recognition and significance of exercise induced arrhythmias and conduction defects are examined. When to convert to pharmacologic stress or add ancillary imaging, including myocardial perfusion imaging, echocardiography, coronary calcium scoring, and magnetic reference imaging are reviewed. The use of stress testing in the management of obstructive and non-obstructive coronary artery disease (CAD), heart failure, cardiac rehabilitation, peripheral vascular disease, congenital heart and other cardiovascular diseases (CVD) is examined. Options to optimize the diagnostic capabilities of exercise and other diagnostic testing for women are highlighted. Strategic use of exercise testing in the face of a decreasing burden of CAD in the developed world, as well as the opportunity to rely on exercise testing as the first test to evaluate CVD in the developing world, are reviewed. The fundamentals of exercise physiology and myocardial ischemia that serve as the foundation for exercise testing in health and disease are explained.


2018 ◽  
pp. 135-148
Author(s):  
Gregory S. Thomas ◽  
Myrvin H. Ellestad

The chapter Exercise Testing Protocols compares the types of protocols available. Historically, exercise testing began with protocols eliciting a submaximal effort. With time, other protocols were developed including intermittent exercise with rest between exercise stages, a ramp protocol with gradually increasing stages, bicycle ergometry, isometric testing and mental stress testing. Given their ability to measure or estimate maximal oxygen consumption (V̇02max) and assess myocardial ischemia during and a peak exercise, maximal treadmill exercise protocols became the most popular. Most commonly used have been those of Bruce, Ellestad, Balke and Ware, Astrand, and Cornell. All successfully achieve maximal workload in a predictable manner.


1991 ◽  
Vol 1 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Seamus Cullen ◽  
David S. Celermajer ◽  
John E. Deanfield

SummaryExercise is of both physical and psychological benefit in children with congenital heart disease, leading to improved cardiovascular fitness and better quality of life. In such children, however, capacity for exercise is often impaired, and there is a risk of exercise-induced mortality or morbidity. We have reviewed the abnormal cardiovascular response to exercise in children with congenital heart defects and postoperative residua, and the role of exercise testing and training in their diagnosis and treatment. Some patients should be excluded absolutely from all but mild regular exercise because of known high risk; for example, those with severe aortic or subaortic stenosis. Other patients should be encouraged to participate in sports without any limitation; for example, those with small left-to-right shunts or mild valvar regurgitation. In many patients strict recommendations cannot be made, and one must consider the individual, the lesion and its hemodynamic implications, and the type and level of exercise contemplated. Children with congenital heart disease should be encouraged to participate in exercise and recreational sport within the limits provided by their cardiovascular defect. Understanding the pathophysiology of these defects, and knowledge of the risk of exercise in certain conditions, will allow the physician to make sensible recommendations for participation in exercise by individual patients.


2019 ◽  
Vol 10 (3) ◽  
pp. 286-291 ◽  
Author(s):  
Jonathan N. Menachem ◽  
Nosheen Reza ◽  
Jeremy A. Mazurek ◽  
Danielle Burstein ◽  
Edo Y. Birati ◽  
...  

Introduction: Treatment of patients with adult congenital heart disease (ACHD) with advanced therapies including heart transplant (HT) is often delayed due to paucity of objective prognostic markers for the severity of heart failure (HF). While the utility of Cardiopulmonary Exercise Testing (CPET) in non-ACHD patients has been well-defined as it relates to prognosis, CPET for this purpose in ACHD is still under investigation. Methods: We performed a retrospective cohort study of 20 consecutive patients with ACHD who underwent HT between March 2010 and February 2016. Only 12 of 20 patients underwent CPET prior to transplantation. Demographics, standard measures of CPET interpretation, and 30-day and 1-year post transplantation outcomes were collected. Results: Patient Characteristics. Twenty patients with ACHD were transplanted at a median of 40 years of age (range: 23-57 years). Of the 12 patients who underwent CPET, 4 had undergone Fontan procedures, 4 had tetralogy of Fallot, 3 had d-transposition of the great arteries, and 1 had Ebstein anomaly. Thirty-day and one-year survival was 100%. All tests included in the analysis had a peak respiratory quotient _1.0. The median peak oxygen consumption per unit time (_VO2) for all diagnoses was 18.2 mL/kg/min (46% predicted), ranging from 12.2 to 22.6. Conclusion: There is a paucity of data to support best practices for patients with ACHD requiring transplantation. While it cannot be proven based on available data, it could be inferred that outcomes would have been worse or perhaps life sustaining options unavailable if providers delayed referral because of the lack of attainment of CPET-specific thresholds.


2013 ◽  
Vol 168 (2) ◽  
pp. 1274-1279 ◽  
Author(s):  
Marco Zimarino ◽  
Luca Barnabei ◽  
Rosalinda Madonna ◽  
Giuseppe Palmieri ◽  
Francesco Radico ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
A. M. Hinson ◽  
C. W. Smith ◽  
E. R. Siegel ◽  
B. C. Stack

The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease.


2008 ◽  
Vol 36 (2) ◽  
pp. 369-374 ◽  
Author(s):  
Panagiotis Baltopoulos ◽  
Charalampos Tsintzos ◽  
George Prionas ◽  
Maria Tsironi

Background Thoracic outlet syndrome is described as a group of distinct disorders producing signs and symptoms attributed to compression of nerves and blood vessels in the thoracic outlet region. Purpose To describe the exercise-induced scalenus anticus syndrome attributed to the anterior scalenus hypertrophy as a thoracic outlet syndrome underlying mechanism and to give recommendations for a safe and effective surgical treatment. Study Design Case series; Level of evidence, 4. Methods Twelve young professional athletes admitted for thoracic outlet syndrome (8 cases of neurologic thoracic outlet syndrome, 4 cases of mixed neurologic and vascular thoracic outlet syndrome) who reported numbness, tingling, early fatigue, muscle weakness, and pain were enrolled in the study. Scalenus hypertrophy was suspected to be the causative factor. Scalenectomy was performed in all cases. Results All patients had moderate to severe hypertrophy of the anterior scalenus muscle. Scalenectomy was performed, and there were no intraoperative or postoperative complications. Full activity was quickly achieved, and no recurrence of symptoms was documented. Conclusion Surgical intervention for scalenus anticus syndrome can allow an athlete to return to full activity and improve quality of life. Surgical intervention seems to be the treatment of choice in terms of restoring quality of life and physical activity.


2016 ◽  
Vol 118 (11) ◽  
pp. 1751-1757 ◽  
Author(s):  
Rupert K. Hung ◽  
Mouaz H. Al-Mallah ◽  
Seamus P. Whelton ◽  
Erin D. Michos ◽  
Roger S. Blumenthal ◽  
...  

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