Behavioral and/or Pharmacotherapy for Older Patients with Insomnia

2018 ◽  
Author(s):  
Robert Ross ◽  
Rajesh R. Tampi
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Older Patients ◽  
Clinical Case ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Healthy Elderly ◽  
Longterm Treatment ◽  
Study Intervention ◽  
Landmark Study

This chapter provides a summary of a landmark study on short and longterm treatment of insomnia. Should older patients with insomnia be managed with cognitive behavioral therapy, benzodiazepines, or both? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case. The study shows that bensodiazepines and cognitive behavioral therapy are equally effective for shorterm treatment of insomnia in otherwise healthy elderly participants but cognitive behavioral therapy is far more effective for longterm treatment of insomnia.

Cognitive Behavioral Therapy, Sertraline, or a Combination in Childhood Anxiety

2018 ◽  
Author(s):  
David Saunders ◽  
Andres Martin ◽  
Jerome H. Taylor
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Anxiety Disorders ◽  
Clinical Case ◽  
Behavioral Therapy ◽  
Childhood Anxiety ◽  
Child And Adolescent Psychiatry ◽  
Cognitive Behavioral ◽  
Study Intervention ◽  
Landmark Study

This chapter provides a summary of a landmark study evaluating the treatment of anxiety disorders in child and adolescent psychiatry. Is sertraline in combination with cognitive behavioral therapy more effective than monotherapy with either treatment alone in children with anxiety disorders? Also, how do these treatments compare with placebo therapy? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

Fluoxetine, Comprehensive Cognitive Behavioral Therapy, and Placebo in Generalized Social Phobia

2018 ◽  
Author(s):  
Erin Habecker ◽  
Tobias Wasser
Keyword(s):  
Combination Therapy ◽  
Cognitive Behavioral Therapy ◽  
Social Phobia ◽  
Clinical Case ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Study Intervention ◽  
Landmark Study ◽  
Generalized Social Phobia

This chapter provides a summary of a landmark study on anxiety disorders. For generalized social phobia, are fluoxetine and comprehensive cognitive behavioral therapy efficacious? How do their efficacies compare? And is there an advantage to combination therapy? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. Results of the study indicate that fluoxetine and comprehensive cognitive behavioral therapy are superior to placebo for the treatment of generalized social phobia; neither treatment is superior to the other and there is no apparent advantage to combination therapy. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

Cognitive Behavioral Therapy, Imipramine, or Their Combination for Panic Disorder

2018 ◽  
Author(s):  
Amanda Sun ◽  
Tobias Wasser
Keyword(s):  
Panic Disorder ◽  
Cognitive Behavioral Therapy ◽  
Anxiety Disorders ◽  
Study Design ◽  
Clinical Case ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Study Intervention ◽  
Landmark Study

This chapter provides a summary of a landmark study on anxiety disorders and the roles of psychotherapy and psychopharmacology in their treatment. When treating adults with panic disorder, is imipramine in combination with cognitive behavioral therapy more effective than monotherapy with either treatment alone? Furthermore, what is the durability and tolerability of their responses? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

The Treatment for Adolescents with Depression Study (TADS)

2018 ◽  
Author(s):  
Zachary Engler ◽  
Zheala Qayyum
Keyword(s):  
Adolescent Psychiatry ◽  
Clinical Case ◽  
Behavioral Therapy ◽  
Child And Adolescent Psychiatry ◽  
Treatment Of Depression ◽  
And Behavior ◽  
Study Intervention ◽  
The Relationship ◽  
Landmark Study

This chapter provides a summary of a landmark study in child and adolescent psychiatry. This study is also notable for addressing the relationship between suicidal thinking and behavior and treatment of depression in adolescents. Among adolescents with depression, is fluoxetine and cognitive behavioral therapy efficacious? If so, how does the efficacy of these treatments compare with each other and in combination? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

RELATED FACTORS TO RELAPSE IN DEPRESSED PATIENTS AFTER COGNITIVE BEHAVIOURAL THERAPY DURING ONE YEAR PROSPECTIVE FOLLOW-UP

2011 ◽  
pp. 13-19
Author(s):  
Nhu Minh Hang Tran ◽  
Huu Cat Nguyen ◽  
Dang Doanh Nguyen ◽  
Van Luong Ngo ◽  
Vu Hoang Nguyen ◽  
...  
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Relapse Rate ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Related Factors ◽  
Depressed Patients ◽  
One Year

Objectives: To determine factors impact on the relapse in depressed patients treated with Cognitive Behavioral Therapy (CBT) during one year follow-up. Materials and Methods: 80 depressed patients divided into two groups, group 1: included 40 patients treated with CBT; group 2: 40 patients on amitriptyline. Non-randomized controlled clinical trial, opened, longiditual and prospective research. Results and Conclusions: relapse rate after CBT during 1 year follow-up is 10% (compared to 25% in control group), related factors to relapse rate in depression after CBT are age and education. Shared predictors between 2 groups are severity and recurrence of depression. Key words: Depression, relapse, Cognitive Behavioral Therapy (CBT)

349 Cognitive Behavioral Therapy for Insomnia in Patients with Chronic Pain - A Systematic Review and Meta-Analysis

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A139-A140
Author(s):  
Janannii Selvanathan ◽  
Chi Pham ◽  
Mahesh Nagappa ◽  
Philip Peng ◽  
Marina Englesakis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Behavioral Therapy ◽  
Cancer Pain ◽  
Behavioral Therapy ◽  
Meta Analysis ◽  
Post Treatment ◽  
Cognitive Behavioral ◽  
Comorbid Insomnia ◽  
Patient Reported

Abstract Introduction Patients with chronic non-cancer pain often report insomnia as a significant comorbidity. Cognitive behavioral therapy for insomnia (CBT-I) is recommended as the first line of treatment for insomnia, and several randomized controlled trials (RCTs) have examined the efficacy of CBT-I on various health outcomes in patients with comorbid insomnia and chronic non-cancer pain. We conducted a systematic review and meta-analysis on the effectiveness of CBT-I on sleep, pain, depression, anxiety and fatigue in adults with comorbid insomnia and chronic non-cancer pain. Methods A systematic search was conducted using ten electronic databases. The duration of the search was set between database inception to April 2020. Included studies must be RCTs assessing the effects of CBT-I on at least patient-reported sleep outcomes in adults with chronic non-cancer pain. Quality of the studies was assessed using the Cochrane risk of bias assessment and Yates quality rating scale. Continuous data were extracted and summarized using standard mean difference (SMD) with 95% confidence intervals (CIs). Results The literature search resulted in 7,772 articles, of which 14 RCTs met the inclusion criteria. Twelve of these articles were included in the meta-analysis. The meta-analysis comprised 762 participants. CBT-I demonstrated a large significant effect on patient-reported sleep (SMD = 0.87, 95% CI [0.55–1.20], p < 0.00001) at post-treatment and final follow-up (up to 9 months) (0.59 [0.31–0.86], p < 0.0001); and moderate effects on pain (SMD = 0.20 [0.06, 0.34], p = 0.006) and depression (0.44 [0.09–0.79], p= 0.01) at post-treatment. The probability of improving sleep and pain following CBT-I at post-treatment was 81% and 58%, respectively. The probability of improving sleep and pain at final follow-up was 73% and 57%, respectively. There were no statistically significant effects on anxiety and fatigue. Conclusion This systematic review and meta-analysis showed that CBT-I is effective for improving sleep in adults with comorbid insomnia and chronic non-cancer pain. Further, CBT-I may lead to short-term moderate improvements in pain and depression. However, there is a need for further RCTs with adequate power, longer follow-up periods, CBT for both insomnia and pain, and consistent scoring systems for assessing patient outcomes. Support (if any):

scholarly journals One-year randomized trial comparing virtual reality-assisted therapy to cognitive–behavioral therapy for patients with treatment-resistant schizophrenia

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Laura Dellazizzo ◽  
Stéphane Potvin ◽  
Kingsada Phraxayavong ◽  
Alexandre Dumais
Keyword(s):  
Virtual Reality ◽  
Cognitive Behavioral Therapy ◽  
Psychiatric Symptoms ◽  
Behavioral Therapy ◽  
Controlled Trial ◽  
Comparative Trial ◽  
Cognitive Behavioral ◽  
Treatment Resistant ◽  
Auditory Verbal Hallucinations

AbstractThe gold-standard cognitive–behavioral therapy (CBT) for psychosis offers at best modest effects. With advances in technology, virtual reality (VR) therapies for auditory verbal hallucinations (AVH), such as AVATAR therapy (AT) and VR-assisted therapy (VRT), are amid a new wave of relational approaches that may heighten effects. Prior trials have shown greater effects of these therapies on AVH up to a 24-week follow-up. However, no trial has compared them to a recommended active treatment with a 1-year follow-up. We performed a pilot randomized comparative trial evaluating the short- and long-term efficacy of VRT over CBT for patients with treatment-resistant schizophrenia. Patients were randomized to VRT (n = 37) or CBT (n = 37). Clinical assessments were administered before and after each intervention and at follow-up periods up to 12 months. Between and within-group changes in psychiatric symptoms were assessed using linear mixed-effects models. Short-term findings showed that both interventions produced significant improvements in AVH severity and depressive symptoms. Although results did not show a statistically significant superiority of VRT over CBT for AVH, VRT did achieve larger effects particularly on overall AVH (d = 1.080 for VRT and d = 0.555 for CBT). Furthermore, results suggested a superiority of VRT over CBT on affective symptoms. VRT also showed significant results on persecutory beliefs and quality of life. Effects were maintained up to the 1-year follow-up. VRT highlights the future of patient-tailored approaches that may show benefits over generic CBT for voices. A fully powered single-blind randomized controlled trial comparing VRT to CBT is underway.

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