Meningitis and meningococcal disease

Author(s):  
Sam Ghebrehewet ◽  
David Conrad ◽  
Gill Marsh

This chapter explores the various causes of meningitis and focuses on meningitis caused by Neisseria meningitidis, which can also result in other invasive illnesses (meningococcal disease, e.g. meningococcal septicaemia/meningococcaemia). Background information on the epidemiology and clinical features of meningococcal disease, the steps and principles that need to be followed for timely implementation of public health actions (antibiotic chemoprophylaxis, Men B; Men C; Men ACWY vaccination, and public health advice) in order to prevent secondary cases following the notification of a single case or cluster in an educational setting (nursery) are discussed. Furthermore, potential public health action(s) that can be considered in dealing with cases of meningococcal disease in different circumstances/situations are covered.

2016 ◽  
Vol 21 (45) ◽  
Author(s):  
Alison Smith-Palmer ◽  
Ken Oates ◽  
Diana Webster ◽  
Sarah Taylor ◽  
Kevin J Scott ◽  
...  

The 23rd World Scout Jamboree was held in Japan from 28 July to 8 August 2015 and was attended by over 33,000 scouts from 162 countries. An outbreak of invasive meningococcal disease capsular group W was investigated among participants, with four confirmed cases identified in Scotland, who were all associated with one particular scout unit, and two confirmed cases in Sweden; molecular testing showed the same strain to be responsible for illness in both countries. The report describes the public health action taken to prevent further cases and the different decisions reached with respect to how wide to extend the offer of chemoprophylaxis in the two countries; in Scotland, chemoprophylaxis was offered to the unit of 40 participants to which the four cases belonged and to other close contacts of cases, while in Sweden chemoprophylaxis was offered to all those returning from the Jamboree. The report also describes the international collaboration and communication required to investigate and manage such multinational outbreaks in a timely manner.


2002 ◽  
Vol 6 (45) ◽  
Author(s):  
E Hoile

New, revised guidelines for the public health management of meningococcal disease have been published in the United Kingdom, as a result of recent changes in the epidemiology of meningococcal disease together with the introduction of new vaccines and an accumulation of new evidence on risk evaluation and control methods (1). The guidelines cover pre-admission management, investigation of suspect cases, the role of public health, public health action after a single case, prophylaxis in healthcare settings and the management of clusters. The guidance contains detailed revisions on the use of antibiotics before admission to hospital, the rationale and indications for chemoprophylaxis, and the use of new vaccines. All recommendations within the review are graded according to the level of evidence on which they are based, probably the first European guidelines to do so (2).


2020 ◽  
Author(s):  
Ignacio Garitano ◽  
Manuel Linares ◽  
Laura Santos ◽  
Ruth Gil ◽  
Elena Lapuente ◽  
...  

UNSTRUCTURED On 28th February a case of COVID-19 was declared in Araba-Álava province, Spain. In Spain, a confinement and movement restrictions were established by Spanish Government at 14th March 2020. We implemented a web-based tool to estimate number of cases during the pandemic. We present the results in Áraba-Álava province. We reached a response rate of 10,3% out a 331.549 population. We found that 22,4 % fulfilled the case definition. This tool rendered useful to inform public health action.


Author(s):  
David A Savitz

Abstract Interpreting the results of epidemiologic studies calls for objectivity and rigorous scrutiny, acknowledging the limitations that temper the applicability of the findings to public health action. Current trends have posed new challenges to balancing goal of scientific objectivity and validity with public health applications. The ongoing tension between epidemiology’s aspirations and capability has several sources: the need to overpromise in research proposals, compromising methodologic rigor because of public health importance, defending findings in the face of hostile critics, and appealing to core constituencies who have specific expectations from the research.


BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e048042
Author(s):  
Andrew Hayward ◽  
Ellen Fragaszy ◽  
Jana Kovar ◽  
Vincent Nguyen ◽  
Sarah Beale ◽  
...  

IntroductionThe coronavirus (COVID-19) pandemic has caused significant global mortality and impacted lives around the world. Virus Watch aims to provide evidence on which public health approaches are most likely to be effective in reducing transmission and impact of the virus, and will investigate community incidence, symptom profiles and transmission of COVID-19 in relation to population movement and behaviours.Methods and analysisVirus Watch is a household community cohort study of acute respiratory infections in England and Wales and will run from June 2020 to August 2021. The study aims to recruit 50 000 people, including 12 500 from minority ethnic backgrounds, for an online survey cohort and monthly antibody testing using home fingerprick test kits. Nested within this larger study will be a subcohort of 10 000 individuals, including 3000 people from minority ethnic backgrounds. This cohort of 10 000 people will have full blood serology taken between October 2020 and January 2021 and repeat serology between May 2021 and August 2021. Participants will also post self-administered nasal swabs for PCR assays of SARS-CoV-2 and will follow one of three different PCR testing schedules based on symptoms.Ethics and disseminationThis study has been approved by the Hampstead National Health Service (NHS) Health Research Authority Ethics Committee (ethics approval number 20/HRA/2320). We are monitoring participant queries and using these to refine methodology where necessary, and are providing summaries and policy briefings of our preliminary findings to inform public health action by working through our partnerships with our study advisory group, Public Health England, NHS and government scientific advisory panels.


2018 ◽  
Vol 46 (22_suppl) ◽  
pp. 48-57 ◽  
Author(s):  
Ditte H. Holt ◽  
Gemma Carey ◽  
Morten H. Rod

Aims: This paper examines the role of organizational structure within government(s) in attempts to implement intersectoral action for health in Danish municipalities. We discuss the implications of structural reorganization and the governance structures that are established in order to ensure coordination and integration between policy sectors. Methods: The paper is based on 49 interviews with civil servants from health and non-health sectors of 10 municipalities. Based on participants’ experiences, cases have been described and analyzed in an iterative process consulting the literature on Health in All Policies and joined-up government. Results: Continuous and frequent processes of reorganizing were widespread in the municipalities. However, they appeared to have little effect on policy change. The two most common governance structures established to transcend organizational boundaries were the central unit and the intersectoral committee. According to the experiences of participants, paradoxically both of these organizational solutions tend to reproduce the organizational problems they are intended to overcome. Even if structural reorganization may succeed in dissolving some sector boundaries, it will inevitably create new ones. Conclusions: It is time to dismiss the idea that intersectoral action for health can be achieved by means of a structural fix. Rather than rearranging organizational boundaries it may be more useful to seek to manage the silos which exist in any organization, e.g. by promoting awareness of their implications for public health action and by enhancing the boundary spanning skills of public health officers.


2010 ◽  
Vol 362 (7) ◽  
pp. 650-652 ◽  
Author(s):  
Lawrence J. Appel ◽  
Cheryl A.M. Anderson

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