Acquired immunodeficiency syndrome (AIDS)

2021 ◽  
pp. 197-212
Author(s):  
Quarraisha Abdool Karim ◽  
Urisha Singh ◽  
Cheryl Baxter ◽  
Salim S. Abdool Karim
Keyword(s):  
Acquired Immunodeficiency Syndrome ◽  
Sexual Transmission ◽  
Hiv Infections ◽  
Antiretroviral Drugs ◽  
People Living With Hiv ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Exposure Prophylaxis ◽  
Living With Hiv

This chapter traces the history of human immunodeficiency virus (HIV) from its origins, remarkable scientific advances, and unprecedented global responses through to the current state of the epidemic, progress towards ending acquired immunodeficiency syndrome (AIDS) and remaining challenges. It explains the origins of HIV-1 and HIV-2, the development of a surveillance system, and the viral structure. It outlines different antiretroviral drugs used in the treatment of HIV infections, and current drug research. The prevention of both mother-to-child transmission and sexual transmission is outlined, including pre-exposure prophylaxis (PrEP) use. The development of modern technologies and social media to help people living with HIV is covered. Programmes to modify behaviour and reduce risk from injecting drug use are explained.

scholarly journals HIV/AIDS SEBAGAI “RUANG” PELAYANAN PASTORAL GEREJA

2020 ◽  
Vol 3 (1) ◽  
pp. 37-46
Author(s):  
Robinson Simanungkalit
Keyword(s):  
Hiv And Aids ◽  
People Living With Hiv ◽  
Proper Understanding ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Living With Hiv ◽  
The Church ◽  
Hiv Aids

It is important to explain some important things on Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS). This study was aimed to to provide a proper understanding on the HIV/AIDS. Consequently, this study described what the HIV/AIDS is, the history of the emergence of HIV/AIDS, the transmission of HIV/AIDS, and the effects of HIV/AIDS on infected human. People infected with HIV and AIDS are referred to as PLWHA (People living with HIV and AIDS). They may be church citizens. Therefore, the church must not "turn a blind eye", but is required to be proactive in responding to people who have infected with HIV/AIDS.BAHASA INDONESIA ABSTRACT: Sangatlah penting untuk menjelaskan beberapa hal penting tentang HIV/AIDS guna memberikan pemahaman yang benar tentang HIV/AIDS. Dibutuhkan penjelasan tentang apa itu HIV/AIDS, Sejarah munculnya HIV/AIDS, Penularan HIV/AIDS dan dampak yang ditimbulkan oleh HIV/AIDS terhadap orang- orang yang terinfeksi. Orang yang terinfeksi HIV dan AIDS itu disebut sebagai ODHA (Orang yang hidup dengan HIV dan AIDS). Mungkin saja mereka adalah warga gereja dan karena itu gereja tidak boleh “menutup mata” tetapi dituntut untuk proaktif dalam menyikapi keberadaan warganya yang terinfeksi HIV/AIDS.Keywords: HIV/AIDS, ODHA

scholarly journals MECHANISM OF HIV PENETRATION

2019 ◽  
Vol 19 (2) ◽  
pp. 235-240
Author(s):  
G.I. Mavrov ◽  
Y.V. Scherbakova ◽  
K. Ye. Ishcheikin ◽  
V.I. Kameniev ◽  
Ya. A. Yemchenko
Keyword(s):  
Human Immunodeficiency Virus ◽  
Acquired Immunodeficiency Syndrome ◽  
Sexual Transmission ◽  
Acute Infection ◽  
Systemic Infection ◽  
Antiretroviral Drugs ◽  
World Health ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Prevention of human immunodeficiency virus transmission through intercourse consists in combining highly effective biomedical, behavioural, and structural interventions. The purpose of this review was to summarize our own and global studies on the sexual transmission of human immunodeficiency virus through the mucous membranes of the genital organs. Global reports of the United Nations agency on the fight against acquired immunodeficiency syndrome, statistical reports of individual countries (in particular, Ukraine), materials of the World Health Organization for the period from 2000 to 2018 were analyzed. Improving and implementing measures to prevent the sexual transmission of human immunodeficiency virus are extremely necessary to halt the global epidemic of acquired immunodeficiency syndrome and to finally overcome it. Studies on animal models and the investigation of acute infection pathogenesis in humans have revealed vulnerabilities in the behaviour of the virus during penetration through the mucous membrane of the genital organs in the very early stages of infection. The data obtained open up new directions for the use of prophylactic vaccines and antiretroviral drugs to prevent the development of systemic infection, with the depletion of CD4 T cells. These studies enabled us to conclude that prevention strategies should target the earliest stages of infection for the following reasons: the vulnerability of the virus, which at an early stage is located in small populations of the founding cells at the site of entry for the infection; in order to develop as a systemic infection, the local spread of the virus is first necessary; the adverse effects that develop rapidly are associated only with a systemic infection. Thus, in near future, the effectiveness of the prevention of human immunodeficiency virus transmitted through sexual intercourse will depend on the solution of scientific and practical issues of immunology.

scholarly journals HIV Infection: What Should We Know?

2020 ◽  
Vol 2 (1) ◽  
pp. 01-16
Author(s):  
Ridwan Balatif
Keyword(s):  
Hiv Infection ◽  
Hiv Transmission ◽  
Opportunistic Infections ◽  
Antiretroviral Drugs ◽  
People Living With Hiv ◽  
Stigma And Discrimination ◽  
Acquired Immunodeficiency ◽  
To Come ◽  
Immunodeficiency Syndrome ◽  
Living With Hiv

Acquired Immunodeficiency Syndrome (AIDS) was first known in 1981 in homosexual groups who had opportunistic infections and malignancies. In Indonesia the first AIDS case was reported in 1987 to a Dutch citizen living in the province of Bali. Cases of HIV infection in Indonesia are reported to increase every year and most occur at the age of 25-49 years. HIV transmission is not easily transmitted, even when an HIV-infected person takes antiretroviral drugs can reduce the risk of transmission by up to 96%. But one of the biggest challenges in managing HIV infection is facing stigma and discrimination. As many as 1 in 5 people living with HIV are afraid to come to the clinic because they will experience discrimination and stigma from the community if this condition occurs will cause treatment delay until PLWHA (People living with HIV/AIDS) will fall to the AIDS stage and PLWHA will be susceptible to opportunistic infections. A clinic in Namibia, when stigma and discrimination were successfully overcome, there was a 20% reduction in mortality in PLWHA

scholarly journals An immigrant with acquired immunodeficiency syndrome presenting with a rash: A case report

2019 ◽  
Vol 7 ◽  
pp. 2050313X1982961
Author(s):  
Connie Zhang ◽  
Megan A Sander
Keyword(s):  
Human Immunodeficiency Virus ◽  
Acquired Immunodeficiency Syndrome ◽  
Systemic Disease ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Laboratory Investigations ◽  
Polymerase Chain ◽  
Immunodeficiency Syndrome ◽  
Work Up

A 58-year-old woman from Zimbabwe, with a history of untreated human immunodeficiency virus, presented with leonine facies and a diffuse rash. The rash occurred in the context of a 1-year history of constitutional symptoms and cognitive decline. Laboratory investigations confirmed that her human immunodeficiency virus had progressed to acquired immunodeficiency syndrome. Through imaging, tissue biopsies, and polymerase chain reaction, a diagnosis of disseminated histoplasmosis was made. Since there was no history of travel and histoplasmosis is not locally endemic, the patient likely contracted this fungal infection more than 7 years ago, while living in Africa. We speculate that the histoplasmosis remained latent until her immune system began to decline. The work-up and management of this rare cutaneous presentation of a systemic disease, which should be added to the list of “great mimickers” in dermatology, are discussed.

Blood in saliva of patients with acquired immunodeficiency syndrome: Possible implication in sexual transmission of the disease

1994 ◽  
Vol 42 (1) ◽  
pp. 38-41 ◽  
Author(s):  
Marcello Piazza ◽  
Antonio Chirianni ◽  
Ludovico Picciotto ◽  
Pietro Tullio Cataldo ◽  
Guglielmo Borgia ◽  
...  
Keyword(s):  
Acquired Immunodeficiency Syndrome ◽  
Sexual Transmission ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Zidovudine and the Natural History of the Acquired Immunodeficiency Syndrome

1991 ◽  
Vol 324 (20) ◽  
pp. 1412-1416 ◽  
Author(s):  
Richard D. Moore ◽  
Julia Hidalgo ◽  
Barbara W. Sugland ◽  
Richard E. Chaisson
Keyword(s):  
Natural History ◽  
Acquired Immunodeficiency Syndrome ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Mechanisms of immune aging in HIV

2022 ◽  
Vol 136 (1) ◽  
pp. 61-80
Author(s):  
Manon Chauvin ◽  
Delphine Sauce
Keyword(s):  
Immune Activation ◽  
Opportunistic Infections ◽  
People Living With Hiv ◽  
Adaptive Immune ◽  
Hiv Progression ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Living With Hiv ◽  
Hiv 1

Abstract Massive CD4+ T-cell depletion as well as sustained immune activation and inflammation are hallmarks of Human Immunodeficiency Virus (HIV)-1 infection. In recent years, an emerging concept draws an intriguing parallel between HIV-1 infection and aging. Indeed, many of the alterations that affect innate and adaptive immune subsets in HIV-infected individuals are reminiscent of the process of immune aging, characteristic of old age. These changes, of which the presumed cause is the systemic immune activation established in patients, likely participate in the immuno-incompetence described with HIV progression. With the success of antiretroviral therapy (ART), HIV-seropositive patients can now live for many years despite chronic viral infection. However, acquired immunodeficiency syndrome (AIDS)-related opportunistic infections have given way to chronic diseases as the leading cause of death since HIV infection. Therefore, the comparison between HIV-1 infected patients and uninfected elderly individuals goes beyond the sole onset of immunosenescence and extends to the deterioration of several physiological functions related to inflammation and systemic aging. In light of this observation, it is interesting to understand the precise link between immune activation and aging in HIV-1 infection to figure out how to best care for people living with HIV (PLWH).

scholarly journals Reduction of CD4 count induces opportunistic infections in people living with HIV (PLHIV)

2014 ◽  
Vol 13 (3) ◽  
pp. 285-291 ◽  
Author(s):  
Rashed Noor ◽  
Md. Morsalin ◽  
Bidhan Chakraborty
Keyword(s):  
Opportunistic Infections ◽  
Medical Science ◽  
Skin Lesions ◽  
The Body ◽  
Cd4 Count ◽  
People Living With Hiv ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Living With Hiv

Objective: Human immunodeficiency virus (HIV), a lentivirus (member of the retrovirus family) causing acquired immunodeficiency syndrome (AIDS), weakens the immune system of the body and hence associates different opportunistic infections. Present study undertook a survey on opportunistic infections. Materials and Methods: Data were collected from both HIV carriers (CD4 count more than 250/mL of blood) and AIDS patients (CD4 count less than 250/mL of blood). Results: Analyses of the data revealed that diarrhoea, pulmonary tuberculosis, gland tuberculosis, skin lesions and fever were the common opportunistic infections. Conclusion: It can be summarized that HIV infected patients having a reduced CD4 count (<250/mL) encounter different opportunistic infections and some of these infections could be continual for long as well. DOI: http://dx.doi.org/10.3329/bjms.v13i3.19151 Bangladesh Journal of Medical Science Vol.13(3) 2014 p.285-291

Sign in / Sign up

Export Citation Format

Share Document