S

2020 ◽  
pp. 718-772
Author(s):  
Sean Ainsworth
Keyword(s):  
Sodium Chloride ◽  
Adverse Effects ◽  
Sodium Bicarbonate ◽  
Sodium Valproate ◽  
Fusidic Acid ◽  
Sodium Benzoate ◽  
Skin Care ◽  
Maternal Treatment ◽  
Sodium Phenylbutyrate

This chapter presents information on neonatal drugs that begin with S, including use, pharmacology, adverse effects, fetal and infant implications of maternal treatment, treatment, and supply of Salbutamol = Albuterol (USAN), Sildenafil, Skin care and skin sterility, Sodium phenylbutyrate and glycerol phenylbutyrate, Sodium benzoate, Sodium bicarbonate, Sodium chloride, Sodium fusidate (fusidic acid), Sodium valproate, Sotalol, Spiramycin, Spironolactone, Stiripentol, Streptokinase, Sucrose, Sulfadiazine = Sulphadiazine (former BAN), Surfactants, and Suxamethonium = Succinylcholine (USAN)

scholarly journals Effect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis: a randomized clinical trial

2020 ◽  
Author(s):  
Dominique M. Bovée ◽  
Lodi C. W. Roksnoer ◽  
Cornelis van Kooten ◽  
Joris I. Rotmans ◽  
Liffert Vogt ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Sodium Chloride ◽  
Kidney Disease ◽  
Sodium Bicarbonate ◽  
Renin Angiotensin System ◽  
Ammonium Excretion ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Endothelin 1 ◽  
Plasma Bicarbonate

Abstract Background Acidosis-induced kidney injury is mediated by the intrarenal renin-angiotensin system, for which urinary renin is a potential marker. Therefore, we hypothesized that sodium bicarbonate supplementation reduces urinary renin excretion in patients with chronic kidney disease (CKD) and metabolic acidosis. Methods Patients with CKD stage G4 and plasma bicarbonate 15–24 mmol/l were randomized to receive sodium bicarbonate (3 × 1000 mg/day, ~ 0.5 mEq/kg), sodium chloride (2 × 1,00 mg/day), or no treatment for 4 weeks (n = 15/arm). The effects on urinary renin excretion (primary outcome), other plasma and urine parameters of the renin-angiotensin system, endothelin-1, and proteinuria were analyzed. Results Forty-five patients were included (62 ± 15 years, eGFR 21 ± 5 ml/min/1.73m2, plasma bicarbonate 21.7 ± 3.3 mmol/l). Sodium bicarbonate supplementation increased plasma bicarbonate (20.8 to 23.8 mmol/l) and reduced urinary ammonium excretion (15 to 8 mmol/day, both P < 0.05). Furthermore, a trend towards lower plasma aldosterone (291 to 204 ng/L, P = 0.07) and potassium (5.1 to 4.8 mmol/l, P = 0.06) was observed in patients receiving sodium bicarbonate. Sodium bicarbonate did not significantly change the urinary excretion of renin, angiotensinogen, aldosterone, endothelin-1, albumin, or α1-microglobulin. Sodium chloride supplementation reduced plasma renin (166 to 122 ng/L), and increased the urinary excretions of angiotensinogen, albumin, and α1-microglobulin (all P < 0.05). Conclusions Despite correction of acidosis and reduction in urinary ammonium excretion, sodium bicarbonate supplementation did not improve urinary markers of the renin-angiotensin system, endothelin-1, or proteinuria. Possible explanations include bicarbonate dose, short treatment time, or the inability of urinary renin to reflect intrarenal renin-angiotensin system activity. Graphic abstract

Effect of sodium bicarbonate and sodium chloride on aggregation and conformation of pork myofibrillar protein

2021 ◽  
Vol 350 ◽  
pp. 129233
Author(s):  
Yan-ping Li ◽  
Xue-hua Zhang ◽  
Fei Lu ◽  
Zhuang-Li Kang
Keyword(s):  
Sodium Chloride ◽  
Sodium Bicarbonate ◽  
Myofibrillar Protein

Lack of relationship between sodium valproate-induced adverse effects and the plasma concentration of its metabolite 2-propylpenten-4-oic acid

1987 ◽  
Vol 32 (2) ◽  
pp. 219-222 ◽  
Author(s):  
M. Paganini ◽  
G. Zaccara ◽  
F. Moroni ◽  
R. Campostrini ◽  
L. Bendoni ◽  
...  
Keyword(s):  
Plasma Concentration ◽  
Adverse Effects ◽  
Sodium Valproate

scholarly journals EFFECT OF SOLAR DEHYDRATION METHOD ON PHYSICO-CHEMICAL AND SENSORY CHARACTERISTICS OF GREEN BEANS (PHASEOLUS VULGARIS)

2017 ◽  
Vol 5 (4RAST) ◽  
pp. 39-44
Author(s):  
Kuna Priyanka ◽  
R.C. Chandni ◽  
Amar Sankar ◽  
A.V. Raghu
Keyword(s):  
Sodium Chloride ◽  
Sodium Bicarbonate ◽  
Magnesium Chloride ◽  
Chemical Characteristics ◽  
Green Beans ◽  
Chemical Treatments ◽  
Physico Chemical ◽  
Nutritional Characteristics ◽  
Microbial Analysis ◽  
Chlorophyll Retention

Studies were done by different chemical treatments under solar dehydration of Green beans. The Green beans were treated by five different methods which are mentioned and the end product was underwent analysis for physico-chemical characteristics, nutritional characteristics, microbial analysis and sensory evaluation. Five treatments of different proportions with Magnesium chloride, Sodium chloride, Sodium bicarbonate and Magnesium oxide were done for solar dehydration of Green beans and (0.1% Magnesium chloride and 0.1% Sodium bicarbonate) treated Green beans were found to be good in all characteristics i.e. Physico-chemical (better chlorophyll retention) and nutritional characteristics when compared to other  treatments.

scholarly journals Evaluating the effects of caffeine and sodium bicarbonate, ingested individually or in combination, and a taste-matched placebo on high-intensity cycling capacity in healthy males

2016 ◽  
Vol 41 (4) ◽  
pp. 354-361 ◽  
Author(s):  
Matthew F. Higgins ◽  
Susie Wilson ◽  
Cameron Hill ◽  
Mike J. Price ◽  
Mike Duncan ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Sodium Bicarbonate ◽  
Body Mass ◽  
High Intensity ◽  
Peak Oxygen Uptake ◽  
Ion Concentration ◽  
Peak Power Output ◽  
Double Blind ◽  
Blood Ph ◽  
Experimental Trials

This study evaluated the effects of ingesting sodium bicarbonate (NaHCO3) or caffeine individually or in combination on high-intensity cycling capacity. In a counterbalanced, crossover design, 13 healthy, noncycling trained males (age: 21 ± 3 years, height: 178 ± 6 cm, body mass: 76 ± 12 kg, peak power output (Wpeak): 230 ± 34 W, peak oxygen uptake: 46 ± 8 mL·kg−1·min−1) performed a graded incremental exercise test, 2 familiarisation trials, and 4 experimental trials. Trials consisted of cycling to volitional exhaustion at 100% Wpeak (TLIM) 60 min after ingesting a solution containing either (i) 0.3 g·kg−1 body mass sodium bicarbonate (BIC), (ii) 5 mg·kg−1 body mass caffeine plus 0.1 g·kg−1 body mass sodium chloride (CAF), (iii) 0.3 g·kg−1 body mass sodium bicarbonate plus 5 mg·kg−1 body mass caffeine (BIC-CAF), or (iv) 0.1 g·kg−1 body mass sodium chloride (PLA). Experimental solutions were administered double-blind. Pre-exercise, at the end of exercise, and 5-min postexercise blood pH, base excess, and bicarbonate ion concentration ([HCO3−]) were significantly elevated for BIC and BIC-CAF compared with CAF and PLA. TLIM (median; interquartile range) was significantly greater for CAF (399; 350–415 s; P = 0.039; r = 0.6) and BIC-CAF (367; 333–402 s; P = 0.028; r = 0.6) compared with BIC (313: 284–448 s) although not compared with PLA (358; 290–433 s; P = 0.249, r = 0.3 and P = 0.099 and r = 0.5, respectively). There were no differences between PLA and BIC (P = 0.196; r = 0.4) or between CAF and BIC-CAF (P = 0.753; r = 0.1). Relatively large inter- and intra-individual variation was observed when comparing treatments and therefore an individual approach to supplementation appears warranted.

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