Antiglucocorticoids in the treatment of affective disorders: from preclinical to clinical studies

2009 ◽  
pp. 345-370
Author(s):  
Sarah E. Gartside ◽  
Keith S. Reid ◽  
I. Nicol Ferrier
Keyword(s):  
Clinical Studies ◽  
Affective Disorders

Trouble Panique et Alcoolisme: Influence de la Comorbidité

1993 ◽  
Vol 38 (7) ◽  
pp. 485-493 ◽  
Author(s):  
J.M. Chignon ◽  
J.P. Lépine
Keyword(s):  
Alcohol Abuse ◽  
Panic Disorder ◽  
Clinical Studies ◽  
Affective Disorders ◽  
Related Disorder ◽  
Addictive Disorders ◽  
Lifetime History ◽  
High Prevalence ◽  
History Of ◽  
History Of Depression

Both epidemiological and clinical studies have demonstrated a high prevalence of panic disorder among alcoholic patients. In contrast, little attention has been given to studying alcohol abuse and/or dependence in patients suffering from panic disorder. One hundred and fifty-five consecutive referrals for treatment for panic disorder were interviewed using a modified version of the Schedule for Affective Disorders and Schizophrenia—Lifetime Version, modified for the study of anxiety disorders. Thirty-two patients (20.7%) had a lifetime history of alcohol abuse and/or dependence. Although the lifetime comorbidity rate of either agoraphobia and/or social phobia seems without any influence on the risk of alcohol-related disorder, alcoholic patients suffering from panic disorder appear to be more likely to have a history of depression and other addictive disorders. The majority of patients with primary alcoholism were male, and those who became alcoholics after they developed panic disorder were more likely to be female. The comparison between patients with primary and secondary alcoholism did not indicate any difference in the comorbidity rate with other psychiatric disorders nor the severity of panic disorder.

scholarly journals Validity of a short clinical interview for psychiatric diagnosis: the mini-SCAN

2010 ◽  
Vol 196 (1) ◽  
pp. 64-68 ◽  
Author(s):  
F. J. Nienhuis ◽  
G. van de Willige ◽  
C. A. Th. Rijnders ◽  
P. de Jonge ◽  
D. Wiersma
Keyword(s):  
Clinical Assessment ◽  
Psychiatric Diagnosis ◽  
Clinical Studies ◽  
Affective Disorders ◽  
Psychotic Disorders ◽  
Focus Of Attention ◽  
System A ◽  
Interview Format ◽  
Valid Instrument ◽  
Level Of Agreement

BackgroundTo promote clinical application of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) system a shorter version (the mini-SCAN) was devised. Its psychometric properties were unknown.AimsTo establish the validity and practical properties of the mini-SCAN.MethodOne hundred and six participants were interviewed twice, once with the SCAN and once with the mini-SCAN. The level of agreement was established for the categories: no disorder, affective disorders, anxiety disorders, non-affective psychotic disorders, affective psychotic disorders.ResultsThe mini-SCAN is a valid instrument. Most kappa values were around 0.90. Only for the class of affective psychotic disorders was the agreement moderate. Mean duration of the mini-SCAN interviews was 25 min shorter than the SCAN interviews. Participants and interviewers were generally satisfied with the interview format and questions.ConclusionsThe mini-SCAN can be used as a diagnostic instrument for clinical purposes and for clinical studies when the present episode is the focus of attention.

Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment

1983 ◽  
Vol 7 (2-3) ◽  
pp. 249-261 ◽  
Author(s):  
Larry J. Siever ◽  
Thomas W. Uhde ◽  
David C. Jimerson ◽  
Marian S. Kafka ◽  
C.Raymond Lake ◽  
...  
Keyword(s):  
Clinical Studies ◽  
Affective Disorders ◽  
Antidepressant Treatment ◽  
Monoamine Receptors

Clinical Studies in Human Strongyloidiasis

1950 ◽  
Vol 16 (4) ◽  
pp. 743-756 ◽  
Author(s):  
Charles A. Jones
Keyword(s):  
Clinical Studies

Exneriana – II – The Scientific Legacy of John E. Exner, Jr. 1Part of this paper was presented at the XIXth International Congress of Rorschach and Projective Methods, July 22–26, 2008, Louvain, Belgium.

2008 ◽  
Vol 29 (2) ◽  
pp. 81-107 ◽  
Author(s):  
Anne Andronikof
Keyword(s):  
Clinical Studies ◽  
Experimental Studies ◽  
Scientific Work ◽  
International Congress ◽  
Response Process ◽  
Scientific Legacy ◽  
Projective Test ◽  
Projective Methods ◽  
Comprehensive Picture ◽  
Complex Mechanisms

Based on an analysis of John Exner’s peer-reviewed published work from 1959 to 2007, plus a brief comment for an editorial in Rorschachiana, the author draws a comprehensive picture of the scientific work of this outstanding personality. The article is divided into three sections: (1) the experimental studies on the Rorschach, (2) the clinical studies using the Rorschach, and (3) Exner’s “testament,” which we draw from the last paper he saw published before his death (Exner, 2001/2002). The experimental studies were aimed at better understanding the nature of the test, in particular the respective roles of perception and projection in the response process. These fundamental studies led to a deeper understanding of the complex mechanisms involved in the Rorschach responses and introduced some hypotheses about the intentions of the author of the test. The latter were subsequently confirmed by the preparatory sketches and documents of Hermann Rorschach, which today can be seen at the H. Rorschach Archives and Museum in Bern (Switzerland). Exner’s research has evidenced the notion that the Rorschach is a perceptive-cognitive-projective test.

Inhibition of Rat Brain Monoamine Oxidase Activities by Psoralen and Isopsoralen: Implications for the Treatment of Affective Disorders

2001 ◽  
Vol 88 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Ling Dong Kong ◽  
Ren Xiang Tan ◽  
Anthony Yiu Ho Woo ◽  
Christopher Hon Ki Cheng2Note
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Affective Disorders ◽  
Brain Monoamine
Sign in / Sign up

Export Citation Format

Share Document