Foundations of clinical practice

Author(s):  
Thomas Hughes

♦ Conscious and unconscious competency♦ Clinical research and the placebo effect♦ Trial design and the randomized controlled trial♦ Critical review of the literature♦ Clinical governance and audit♦ Capacity and consent♦ Principles of teaching and learning.

2017 ◽  
Vol 68 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Mark Georgy ◽  
Mark Stern ◽  
Kieran Murphy

This review presents a summary of the pathology and epidemiology of Modic changes and the possible role of Propionibacterium acnes. This information is followed by a synthesis of the most recent clinical research involved in culturing the discs of patients with degenerative disc disease for the presence of bacteria. We also discuss a randomized controlled trial that investigates the effects of antibiotics on patients with chronic low back pain and type 1 Modic changes. We conclude with a brief discussion of the difficulties involved in this research and the significance of the findings.


2020 ◽  
Vol 96 ◽  
pp. 106105
Author(s):  
Manfred Diehl ◽  
Abigail Nehrkorn-Bailey ◽  
Katherine Thompson ◽  
Diana Rodriguez ◽  
Kaigang Li ◽  
...  

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