scholarly journals Dynamical evolution of multiple-population globular clusters

2021 ◽  
Vol 502 (3) ◽  
pp. 4290-4304
Author(s):  
Enrico Vesperini ◽  
Jongsuk Hong ◽  
Mirek Giersz ◽  
Arkadiusz Hypki
Keyword(s):  
Structural Properties ◽  
Globular Clusters ◽  
First Generation ◽  
Radial Profile ◽  
Dynamical Evolution ◽  
Evolutionary Phase ◽  
Dynamical Parameters ◽  
Energy Equipartition

ABSTRACT We have carried out a set of Monte Carlo simulations to study a number of fundamental aspects of the dynamical evolution of multiple stellar populations in globular clusters with different initial masses, fractions of second generation (2G) stars, and structural properties. Our simulations explore and elucidate: (1) the role of early and long-term dynamical processes and stellar escape in the evolution of the fraction of 2G stars and the link between the evolution of the fraction of 2G stars and various dynamical parameters; (2) the link between the fraction of 2G stars inside the cluster and in the population of escaping stars during a cluster’s dynamical evolution; (3) the dynamics of the spatial mixing of the first-generation (1G) and 2G stars and the details of the structural properties of the two populations as they evolve toward mixing; (4) the implications of the initial differences between the spatial distribution of 1G and 2G stars for the evolution of the anisotropy in the velocity distribution and the expected radial profile of the 1G and 2G anisotropy for clusters at different stages of their dynamical history; and (5) the variation of the degree of energy equipartition of the 1G and the 2G populations as a function of the distance from the cluster’s centre and the cluster’s evolutionary phase.

THE ROLE OF POLYETHYLENIMINE IN ENHANCING PERFORMANCE OF GLUTAMATE BIOSENSORS

2018 ◽  
Vol 8 (3) ◽  
pp. 36-41
Author(s):  
Diep Do Thi Hong ◽  
Duong Le Phuoc ◽  
Hoai Nguyen Thi ◽  
Serra Pier Andrea ◽  
Rocchitta Gaia
Keyword(s):  
First Generation ◽  
Good Reproducibility ◽  
Complex Matrices ◽  
Long Term Stability ◽  
In Vitro Characterization ◽  
Glutamate Oxidase

Background: The first biosensor was constructed more than fifty years ago. It was composed of the biorecognition element and transducer. The first-generation enzyme biosensors play important role in monitoring neurotransmitter and determine small quantities of substances in complex matrices of the samples Glutamate is important biochemicals involved in energetic metabolism and neurotransmission. Therefore, biosensors requires the development a new approach exhibiting high sensibility, good reproducibility and longterm stability. The first-generation enzyme biosensors play important role in monitoring neurotransmitter and determine small quantities of substances in complex matrices of the samples. The aims of this work: To find out which concentration of polyethylenimine (PEI) exhibiting the most high sensibility, good reproducibility and long-term stability. Methods: We designed and developed glutamate biosensor using different concentration of PEI ranging from 0% to 5% at Day 1 and Day 8. Results: After Glutamate biosensors in-vitro characterization, several PEI concentrations, ranging from 0.5% to 1% seem to be the best in terms of VMAX, the KM; while PEI content ranging from 0.5% to 1% resulted stable, PEI 1% displayed an excellent stability. Conclusions: In the result, PEI 1% perfomed high sensibility, good stability and blocking interference. Furthermore, we expect to develop and characterize an implantable biosensor capable of detecting glutamate, glucose in vivo. Key words: Glutamate biosensors, PEi (Polyethylenimine) enhances glutamate oxidase, glutamate oxidase biosensors

Kinematical evolution of Globular Clusters

2019 ◽  
Vol 14 (S351) ◽  
pp. 524-527
Author(s):  
Maria A. Tiongco ◽  
Enrico Vesperini ◽  
Anna Lisa Varri
Keyword(s):  
Angular Momentum ◽  
Structural Properties ◽  
Globular Clusters ◽  
Velocity Dispersion ◽  
Three Dimensional ◽  
Stellar Populations ◽  
Velocity Space ◽  
Fundamental Understanding

AbstractWe present several results of the study of the evolution of globular clusters’ internal kinematics, as driven by two-body relaxation and the interplay between internal angular momentum and the external Galactic tidal field. Via a large suite of N-body simulations, we explored the three-dimensional velocity space of tidally perturbed clusters, by characterizing their degree of velocity dispersion anisotropy and their rotational properties. These studies have shown that a cluster’s kinematical properties contain distinct imprints of the cluster’s initial structural properties, dynamical history, and tidal environment. Building on this fundamental understanding, we then studied the dynamics of multiple stellar populations in globular clusters, with attention to the largely unexplored role of angular momentum.

scholarly journals AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients

2019 ◽  
Vol 8 (4) ◽  
pp. 367-377 ◽  
Author(s):  
Adrian F Daly ◽  
Liliya Rostomyan ◽  
Daniela Betea ◽  
Jean-François Bonneville ◽  
Chiara Villa ◽  
...  
Keyword(s):  
First Generation ◽  
Follicular Thyroid Carcinoma ◽  
Somatostatin Analogs ◽  
Hormonal Control ◽  
Interacting Protein ◽  
Aryl Hydrocarbon ◽  
Tumor Residue ◽  
Baseline Levels

Acromegaly is a rare disease due to chronic excess growth hormone (GH) and IGF-1. Aryl hydrocarbon receptor interacting protein (AIP) mutations are associated with an aggressive, inheritable form of acromegaly that responds poorly to SST2-specific somatostatin analogs (SSA). The role of pasireotide, an SSA with affinity for multiple SSTs, in patients with AIP mutations has not been reported. We studied two AIP mutation positive acromegaly patients with early-onset, invasive macroadenomas and inoperable residues after neurosurgery. Patient 1 came from a FIPA kindred and had uncontrolled GH/IGF-1 throughout 10 years of octreotide/lanreotide treatment. When switched to pasireotide LAR, he rapidly experienced hormonal control which was associated with marked regression of his tumor residue. Pasireotide LAR was stopped after >10 years due to low IGF-1 and he maintained hormonal control without tumor regrowth for >18 months off pasireotide LAR. Patient 2 had a pituitary adenoma diagnosed when aged 17 that was not cured by surgery. Chronic pasireotide LAR therapy produced hormonal control and marked tumor shrinkage but control was lost when switched to octreotide. Tumor immunohistochemistry showed absent AIP and SST2 staining and positive SST5. Her AIP mutation positive sister developed a 2.5 cm follicular thyroid carcinoma aged 21 with tumoral loss of heterozygosity at the AIP locus and absent AIP staining. Patients 1 and 2 required multi-modal therapy to control diabetes. On stopping pasireotide LAR after >10 years of treatment, Patient 1’s glucose metabolism returned to baseline levels. Long-term pasireotide LAR therapy can be beneficial in some AIP mutation positive acromegaly patients that are resistant to first-generation SSA.

The range of UV upturn strengths in early-type galaxies can be caused by dissolved metal-rich Globular Clusters

2019 ◽  
Vol 14 (S351) ◽  
pp. 112-116
Author(s):  
Paul Goudfrooij
Keyword(s):  
Globular Clusters ◽  
Dynamical Evolution ◽  
Virgo Cluster ◽  
Host Galaxy ◽  
Early Type ◽  
Luminosity Functions ◽  
Central Regions ◽  
Specific Frequency ◽  
Uv Upturn

AbstractI summarize the scenario by Goudfrooij (2018) in which the bulk of the ultraviolet (UV) upturn of giant early-type galaxies (ETGs) is due to helium-rich stellar populations that formed in massive metal-rich globular clusters (GCs) and subsequently dissolved in the strong tidal field in the central regions of the massive host galaxy. These massive GCs are assumed to show UV upturns similar to those observed recently in M87, the central galaxy in the Virgo cluster of galaxies. Data taken from the literature reveals a strong correlation between the strength of the UV upturn and the specific frequency of metal-rich GCs in ETGs. Adopting a Schechter function parametrization of GC mass functions, simulations of long-term dynamical evolution of GC systems show that this correlation can be explained by variations in the characteristic truncation mass Mc such that Mc increases with ETG luminosity in a way that is consistent with observed GC luminosity functions in ETGs. These findings suggest that the nature of the UV upturn in ETGs and the variation of its strength among ETGs are causally related to that of helium-rich populations in massive GCs, rather than intrinsic properties of field stars in ETGs.

scholarly journals Stellar-mass Black Holes in Globular Clusters: Dynamical consequences and observational signatures

2019 ◽  
Vol 14 (S351) ◽  
pp. 395-399 ◽  
Author(s):  
Abbas Askar ◽  
Mirek Giersz ◽  
Manuel Arca Sedda ◽  
Ammar Askar ◽  
Mario Pasquato ◽  
...  
Keyword(s):  
Black Holes ◽  
Globular Clusters ◽  
Dynamical Evolution ◽  
Stellar Mass ◽  
Large Set ◽  
Term Survival ◽  
Central Surface ◽  
Sizeable Number ◽  
Hubble Time

AbstractSizeable number of stellar-mass black holes (BHs) in globular clusters (GCs) can strongly influence the dynamical evolution and observational properties of their host cluster. Using results from a large set of numerical simulations, we identify the key ingredients needed to sustain a sizeable population of BHs in GCs up to a Hubble time. We find that while BH natal kick prescriptions are essential in determining the initial retention fraction of BHs in GCs, the long-term survival of BHs is determined by the size, initial central density and half-mass relaxation time of the GC. Simulated GC models that contain many BHs are characterized by relatively low central surface brightness, large half-light and core radii values. We also discuss novel ways to compare simulated results with available observational data to identify GCs that are most likely to contain many BHs.

scholarly journals Star cluster dynamics

2010 ◽  
Vol 368 (1913) ◽  
pp. 829-849 ◽  
Author(s):  
Enrico Vesperini
Keyword(s):  
Globular Clusters ◽  
Cluster Formation ◽  
Cluster Structure ◽  
Dynamical Evolution ◽  
Star Cluster ◽  
Stellar Content ◽  
Cluster Systems ◽  
Detailed Understanding ◽  
Term Evolution

Dynamical evolution plays a key role in shaping the current properties of star clusters and star cluster systems. A detailed understanding of the effects of evolutionary processes is essential to be able to disentangle the properties that result from dynamical evolution from those imprinted at the time of cluster formation. In this review, I focus my attention on globular clusters, and review the main physical ingredients driving their early and long-term evolution, describe the possible evolutionary routes and show how cluster structure and stellar content are affected by dynamical evolution.

scholarly journals HST's hunt for intermediate-mass black holes in star clusters

2009 ◽  
Vol 5 (S266) ◽  
pp. 231-237 ◽  
Author(s):  
Julio Chanamé ◽  
Justice Bruursema ◽  
Rupali Chandar ◽  
Jay Anderson ◽  
Roeland van der Marel ◽  
...  
Keyword(s):  
Black Holes ◽  
Globular Clusters ◽  
Star Clusters ◽  
Dynamical Evolution ◽  
Dynamical Analysis ◽  
Intermediate Mass ◽  
Data Set ◽  
Upper Limits ◽  
Intermediate Mass Black Holes

AbstractEstablishing or ruling out, either through solid mass measurements or upper limits, the presence of intermediate-mass black holes (IMBHs; with masses of 102 − 105 M⊙) at the centers of star clusters would profoundly impact our understanding of problems ranging from the formation and long-term dynamical evolution of stellar systems, to the nature of the seeds and the growth mechanisms of supermassive black holes. While there are sound theoretical arguments both for and against their presence in today's clusters, observational studies have so far not yielded truly conclusive IMBH detections nor upper limits. We argue that the most promising approach to solving this issue is provided by the combination of measurements of the proper motions of stars at the centers of Galactic globular clusters and dynamical models able to take full advantage of this type of data set. We present a program based on HST observations and recently developed tools for dynamical analysis designed to do just that.

scholarly journals Dynamics of primordial binary stars in multiple-population globular clusters

2014 ◽  
Vol 10 (S312) ◽  
pp. 237-238
Author(s):  
Jongsuk Hong ◽  
Enrico Vesperini ◽  
Antonio Sollima ◽  
Steve McMillan ◽  
Franca D'Antona ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Binding Energy ◽  
Binary Stars ◽  
Globular Clusters ◽  
First Generation ◽  
Dynamical Evolution ◽  
Binary Number ◽  
High Binding Energy ◽  
Number Ratio ◽  
Multiple Population

AbstractWe have performed a survey of N-body simulations to explore the dynamics of primordial binaries in multiple-population globular clusters. We show that, as a consequence of the initial differences between the spatial distribution of first-generation (FG) and second-generation (SG) stars, SG binaries are disrupted more efficiently than FG binaries. The effects of dynamical evolution on the surviving binaries produces a difference between the SG and the FG binary binding energy distribution with the SG population characterized by a larger fraction of high binding energy (more bound) binaries. We also explore the evolution of the radial variation of the SG-to-FG binary number ratio and find that although the global binary fraction decreases more rapidly for the SG population, the local binary fraction measured in the cluster inner regions may still be dominated by SG binaries.

scholarly journals Massive stellar systems: observational challenges and perspectives in the E-ELT era

2015 ◽  
Vol 12 (S316) ◽  
pp. 36-43 ◽  
Author(s):  
G. Bono ◽  
V. F. Braga ◽  
I. Ferraro ◽  
G. Fiorentino ◽  
R. Gilmozzi ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
Globular Clusters ◽  
First Generation ◽  
Main Sequence ◽  
Near Infrared ◽  
Galactic Center ◽  
Pros And Cons ◽  
Absolute Age ◽  
The Impact

AbstractWe introduce the empirical framework concerning optical and near-infrared (NIR) photometry of crowded stellar fields. In particular, we address the impact that linear detectors and analytical PSF played in improving the accuracy and the precision of multi-band color-magnitude diagrams (CMDs). We focus our attention on recent findings based on deep NIR images collected with Adaptive Optics (AO) systems at the 8-10m class telescopes and discuss pros and cons of the different approaches. We also discuss the estimate of the absolute age of globular clusters using a well defined knee along the lower main sequence. We mention the role which the current AO-assisted instruments will have in addressing longstanding astrophysical problems of the Galactic center. Finally, we outline the role of first generation of E-ELT instruments upon photometry and spectroscopy of crowded stellar fields.

scholarly journals Extended Surveys of MC Star Clusters

1994 ◽  
Vol 161 ◽  
pp. 497-501
Author(s):  
M. Kontizas ◽  
E. Kontizas
Keyword(s):  
Globular Clusters ◽  
Massive Star ◽  
Binary Star ◽  
Age Distribution ◽  
Star Clusters ◽  
Dynamical Evolution ◽  
Extended System ◽  
Dynamical Parameters ◽  
Stellar Associations ◽  
Early Phases

The location of the LMC clusters, their age distribution and dynamical parameters have shown that two star cluster systems exist in this galaxy: 1) one extended system, elliptical in shape, which contains all intermediate and old star clusters and 2) another system, again elliptical, but smaller in diameter, superimposed on the other and inclined by about 50 degrees from the latter. It contains the most massive, very young globular clusters which are still at their early phases of dynamical evolution. The existence of very rich stellar associations, binary star clusters and very elliptical ones located in this system, indicates that massive star clusters have formed very recently and are still under formation.

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