scholarly journals P0319DEPRESSIVE BURDEN, QUALITY OF LIFE AND CAREGIVER BURDEN IN END STAGE RENAL DISEASE - A PARADIGMATIC SHIFT IN HOLISTIC MANAGEMENT

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Abdul waheed Khan ◽  
Shahbaz ali Khan ◽  
Deepak Shanker Ray ◽  
Swetanka Prasad ◽  
Shagufta Khan ◽  
...  

Abstract Background and Aims Depressive illness is not only common in patients of End Stage Renal Disease (ESRD) but also an independent risk factor for morbidity and mortality. The relation between depressive illness, Quality of Life and caregiver burden in this vulnerable group is complex. We attempted to study these 3 important psychosocial domains in patients of ESRD on hemodialysis, peritoneal dialysis as well as those ESRD patients who were not on any dialysis yet Method A cross sectional analytical comparative controlled design was done to compare 3 domains of depressive burden, quality of life and caregiver burden in 3 group of patients – ESRD patients on hemodialysis, ESRD patients on peritoneal dialysis and ESRD patients not on any dialysis Statistical methods used - χ2 statistic or Fisher‘s exact test for categorical variables and comparison of group means. ANOVA was used for continuous variables where more than 3 groups were compared. Correlational analysis done using Spearman’s correlation coefficient . A p-value of <0.05 was considered significant. SPSS 20.0 was used Results Depressive symptoms were present significantly across all 3 groups of ESRD. Depressive disorder was significantly higher in the Hemodialysis group (HD) as compared to peritoneal dialysis (PD) group( p=0.038). Mean QOL was significantly higher for PD. Caregiver burden was higher in the HD group. The study brought out the huge burden of depressive symptoms and depressive illness in patients on ESRD across all 3 group of patients and the significantly higher burden of depressive illness and lower QoL and higher caregiver burden in the hemodialysis group. This assumes significance because the majority of our ESRD patients are on HD Conclusion This depressive burden is the hidden factor behind poor Quality of Life as well as poor overall satisfaction as well as treatment outcome in our patients of ESRD whether or not on dialysis. Apart from the inherent factors related to the illness or the type of dialysis, sociodemographic factors seem to play a role in QoL and CG burden in the hemodialyis group. To address this hidden depressive burden comprehensively, we recommend closer cooperation between nephrologist, psychiatrist and psychosocial workers to improve the overall treatment outcome in ESRD patients.

2015 ◽  
Vol 12 (1) ◽  
pp. 62-64
Author(s):  
Lidija Orlic ◽  
Ivana Mikolasevic ◽  
Branka Sladoje-Martinovic ◽  
Ivan Bubic and Sanjin Racki

Abstract The number of elderly patients with chronic kidney disease (CKD) as well as those with end-stage renal disease (ESRD) are increasing worldwide. Renal transplantation is now the treatment of choice for all ESRD patients, including those that are aged 65 or over. Namely, there is a growing evidence that elderly patients, in the absence of contraindications, have better outcomes after renal transplantation than alternative forms of RRT. Although survival, quality of life and economic advantages have been shown after transplantation, renal transplantation is still infrequently offered to older patients. Hereby, we present a case of an old woman who was transplanted in 1994 when “senior” program was still not established and when kidney transplantation at this age was rarity in many countries. She lived 16 years and 8 months with a well-functioning graft and died at the age of 89.


2021 ◽  
Author(s):  
Fei Yang ◽  
Zheng Yang ◽  
Lu Cheng ◽  
Jiayu Tong ◽  
Pusheng Wang

Abstract Purpose. Patients with end-stage renal disease (ESRD) face various physical and mental limitations resulting from different renal replacement therapy (RRT) modalities. Renal transplantation (Tx) is considered as the treatment that impacts most on health-related quality of life (HRQOL). This study aimed to analyze and compare the HRQOL and depression levels of patients undergoing hemodialysis (HD), peritoneal dialysis (PD) and Tx.Methods. A single-center cross-sectional sample of 112 HD patients, 68 PD patients and 97 Tx patients participated in our questionnaire survey. The HRQOL and depression levels were assessed through the 36-Item Short-Form Health Survey (SF-36) and Mental Health Inventory (MHI-5), respectively. The multiple linear regression model was performed to examine the factors associated with each of the HRQOL scale scores. Results. The SF-36 HRQOL of Tx patients differed significantly from that in HD and PD groups in all eight dimensions and two components (all P<0.001). More than 45% of patients in each group were facing depressive symptoms. HD patients (63.4%) and PD (67.6%) patients were more depressive compared with Tx patients (45.4%, P =0.006). Depression in ESRD patients contributed to a worse quality of life (P<0.001). Patients ranging in age from 31 to 50, having full-time jobs, receiving Tx and without depression were associated with better HRQOL in the domain of Physical Component Scores (PCS). Patients with unemployment, dismissal or being looking for a job, receiving Tx and without depression were associated with better HRQOL in the domain of Mental Component Scores (MCS).Conclusions. Tx patients had better HRQOL and less depressive symptoms than HD and PD patients. Depression was related to an impaired HRQOL, which was common in ESRD patients. The severity of depression in ESRD patients and the effectiveness of Tx on HRQOL improvement need to be underscored.


2020 ◽  
Vol 66 (9) ◽  
pp. 1229-1234
Author(s):  
Lijuan Zhang ◽  
Yannan Guo ◽  
Hua Ming

SUMMARY OBJECTIVE: To evaluate the effects of hemodialysis, peritoneal dialysis, and renal transplantation on the quality of life of patients with end-stage renal disease (ESRD) and analyze the influencing factors. METHODS: A total of 162 ESRD patients who received maintenance hemodialysis, continuous ambulatory peritoneal dialysis, and renal transplantation from February 2017 to March 2018 in our hospital were divided into a hemodialysis group, a peritoneal dialysis group, and a renal transplantation group. The baseline clinical data, serum indices, as well as environmental factors such as education level, marital status, work, residential pattern, household income, and expenditure were recorded. The quality of life was assessed using the short-form 36-item (SF-36) scale reflecting the Physical Component Summary (PCS) and the Mental Component Summary (MCS). One-way analysis of variance and logistic stepwise multiple regression analysis were performed to analyze the factors influencing the quality of life. RESULTS: The renal transplantation group had the highest average scores for all dimensions of the SF-36 scale. The PCS and MCS scores of this group were higher than those of the hemodialysis and peritoneal dialysis groups. The peritoneal dialysis group had higher scores for physical functioning, physical role, bodily pain, general health, mental health, PCS, and MCS than those of the hemodialysis group. Age, HGB, GLU, and ALP were the main factors influencing PCS. Age, education level, residential pattern, medication expenditure, and monthly per capita income mainly affected MCS. CONCLUSION: In terms of quality of life, renal transplantation is superior to peritoneal dialysis and hemodialysis.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
M. Hanif Prasetya 'Adhi ◽  
Yanny Trisyani ◽  
Etika Emaliyawati

Introduction: ESRD adalah diagnosis akhir yang membutuhkan terapi pengganti ginjal seumur hidup seperti hemodialisa, peritoneal dialysis (PD) dan transplantasi ginjal. Populasi di dunia dan prevalensi penyakit ginjal stadium akhir terus meningkat, pasien semakin dihadapkan dengan keputusan untuk memulai terapi pengganti ginjal. Penelitian dan literature review yang menilai dampak perawatan terapi PD pada pasien ESRD masih terbatas. Tujuan dari literature review ini untuk menganalisis terapi CAPD pada pasien ESRD. Pencarian terbatas pada database elektronik seperti Pubmed, Proquest, dan Google Scholar, dengan kata kunci “ESRD”,”CAPD”,“Peritoneal Dialysis”,“Quality of Life” disusun berdasarkan MeSH Database dari NCBI. Methods: Strategi review artikel menggunakan PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analyses) dan dianalisa menggunakan konten analisis. Studi yang diterbitkan antara tahun 2009-2019, artikel penelitian dengan bahasa inggris, dipertimbangkan sebagai kriteria inklusi dalam tinjauan ini. Results: Didapatkan 25 artikel; 15 kuantitatif, 7 kualitatif, 2 case report dan 1 mixed methods. Discussion: Domain fisik; PD memberikan kelebihan pada peran-fisik, vitalitas, energik, dan bebas nyeri. Domain psikologis; PD menimbulkan depresi dan kecemasan yang lebih rendah daripada HD, bahkan 1 studi menyebutkan HD dapat menyebabkan depresi berat. Hubungan sosial; PD memberikan kemandirian pada gaya hidup, efikasi diri, kebebasan beraktivitas, fleksibilitas, dan mempertahankan kehidupan normal. Hubungan terkait lingkungan; pasien dengan PD lebih mungkin untuk melanjutkan pekerjaan mereka sehingga mereka secara finansial lebih baik dan lebih bebas untuk bepergian daripada HD, penghasilan terus dapat secara signifikan berkontribusi pada kesejahteraan pasien CAPD. Conclusion: PD terbukti memberikan kualitas hidup yang lebih baik. Dengan demikian, penting untuk mengembangkan terapi PD pada pasien ESRD yang membutuhkan dialisis jangka panjang, bahkan seumur hidup.


2020 ◽  
Vol 3 (2) ◽  
pp. 93-103
Author(s):  
Abdelaali Bahadi ◽  
Sanaa Benbria ◽  
Hicham Rafik ◽  
Driss El Kabbaj

Abstract : Introduction: Peritoneal dialysis (PD) is as effective as hemodialysis and often provides a better quality of life for patients. Despite this, the replacement therapy remains little established in our country with a prevalence of less than 1% of patients with end-stage renal disease. The objective of this work is to report the development and complications of PD in our center. Patients and methods: This is a retrospective study including all patients on PD between October 2008 and March 2019. We noted their demographic and clinical data at their initiation in peritoneal dialysis and we followed their evolution to discuss infectious and mechanical complications as well as the causes of PD exit. Results: During the study period, 456 patients were admitted for end-stage renal disease. Among these patients, only 28 (6.1%) were put on PD including two diabetics. Their average age was 37.7 years with a sex ratio of 0.8. The average body surface area was 1.59 m² with an average residual renal function of 6.05 ml / min. PD was chosen as the first intention in 20 patients while 8 patients were on hemodialysis. The evolution was marked by a median survival of the technique of 18.5 months characterized by 8 episodes of peritonitis in 4 patients corresponding to a rate of 1 episode over 56 months. Regarding mechanical complications, we noted 9 omentum aspirations, 1 leak in one case and 1 umbilical hernia requiring surgical recovery in a patient. Out of 28 patients, 17 discharges were identified; 10 patients (67%) were transferred to hemodialysis, 4 died and only 3 patients (18%) were transplanted. The final transfer to hemodialysis was related to mechanical complications in 5 cases, loss of ultrafiltration in one case, repeated hydro-sodium overload in one case, peritonitis in one case and social reasons in two cases. Conclusion: PD is an effective technique which preserves residual renal function and quality of life but its prevalence remains low in the order of 6% of patients treated for end-stage renal disease. The complications are dominated in our context by the mechanical complications main cause of final transfer in hemodialysis.


2021 ◽  
Vol 60 (1) ◽  
Author(s):  
K Promsakun ◽  
◽  
N Yingchankul ◽  

Objectives To study the prevalence of and factors related to caregiver burden amongst caregivers of end-stage renal disease patients. Methods A cross-sectional study was conducted in which data was collected from July 2019 to December 2019 from a total of 152 caregivers aged 18 years and over recruited into this study. Paid caregivers were excluded. The data collected included patient factors, caregiver factors, social support assessment, the Thai version of the Zarit Burden Interview for assessing caregiver burden along with the EQ-5D-5L questionnaire for assessing quality of life. . Results The prevalence of caregiver burden in cases of end-stage renal disease was 18.42%. Factors associated with caregiver burden included single or divorced status, inadequate income, owing money, need for more information and knowledge in caring for patients, low social support, and low quality of life (p < 0.05). Conclusion Caregiver burden screening should be done for individuals providing end-stage chronic kidney disease care including their need for additional information on patient care as well as their economic and social situation. It is important that caregivers be screened as well as supervised. Chiang Mai Medical Journal 2021;60(1):41-52. doi 10.12982/CMUMEDJ.2021.04


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