scholarly journals SP675CORRELATION OF ABDOMINAL AORTIC CALCIFICATION WITH CARDIAC HYPERTROPHY, PULSE PRESSURE AND MINERAL AND BONE DISEASE BIOCHEMISTRIES IN HEMODIALYSIS PATIENTS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii601-iii601
Author(s):  
Dimitra Bacharaki ◽  
Giannis Griveas ◽  
Kiriaki Stamatelou
2019 ◽  
Vol 7 (5) ◽  
pp. 721-725 ◽  
Author(s):  
Riri Andri Muzasti ◽  
Ricke Loesnihari

BACKGROUND: Although the prevalence of cardiovascular disease decreases in the general population, this pattern is not followed in hemodialysis patients. Hence cardiovascular events still occur in 50% of cases resulting in hemodialysis patients. One of the risk factors is vascular calcification. The pathogenesis is not yet fully understood, but recent years studies have shown that vascular calcification in chronic kidney disease (CKD) occurs as a result of the interaction of stimulatory and inhibitory factors. One of the inhibitory factors is Fetuin-A. Until now there has been no data on levels of Fetuin-A as a risk factor for abdominal aortic calcification in Indonesia. AIM: To determine the effect of Fetuin-A levels on abdominal aortic calcification in regular hemodialysis patients. METHODS: This study was a cross-sectional study on 76 regular hemodialysis patients at Rasyida Renal Hospital Medan. Fetuin-A level was examined by enzyme-linked immunosorbent assay (ELISA). Assessment of abdominal aortic calcification was done by lateral lumbar X-ray. RESULTS: Most patients (68.4%) had abdominal aortic calcification, in both layers; intima and media (44.7%). Abdominal aortic calcification was associated with Fetuin-A level and age. Multivariate analysis showed that high Fetuin-A levels were significantly associated with abdominal aortic calcification. CONCLUSION: High Fetuin-A level appeared to be a protective factor against abdominal aortic calcification in regular hemodialysis patients in Indonesia.


2021 ◽  
Author(s):  
Jin He ◽  
Shubei Chen ◽  
Kewen Mao ◽  
Xiaoyan Sun ◽  
Rongjian Nie

Abstract Vascular calcification (VC) and secondary hyperparathyroidism (SHPT) are important causes of high incidence of cardiovascular events in chronic kidney disease (CKD) patients. The relationship between parathyroid hormone (PTH) and VC is very complex. Different studies have inconsistent reports on the effect of PTH on VC. The present study investigated the correlation between PTH levels and abdominal aortic calcification (AAC) in incident hemodialysis patients who did not receive calcium, calcium-containing phosphorus binders, calcitriol or vitamin D analogs. Our data confirm that serum PTH levels is significantly negatively correlated with AAC within a certain concentration range in incident hemodialysis patients who not treated with calcium or vitamin D.


2017 ◽  
Vol 68 (1) ◽  
pp. 1059-1068
Author(s):  
Tamer Mohamed Ragb ◽  
Ahmad Alaa Eldin Ahmad Saad ◽  
Moneir Osman Amin Abd Elaal

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