A Ghost in the Machine
This chapter describes the neurobiological approach of decision-making. Until the late 1980s, ignoring the work of experimental economists and behaviourists, electrophysiologists restricted themselves to the study of sensory and motor function, believing it to be impossible for them to access cognitive processes. In 1989, William Newsome and Anthony Movshon broke the dogma while studying the role of neurons in the medio-temporal area of the cortex (an associative visual area) in the visual discrimination of macaques. They became the first researchers who were able to correlate decision-making with a pattern of electrophysiological activity in neurons. This correlation, which they called psychometric–neurometric pairing, became the backbone of all subsequent studies into the neurobiology of decision-making. The chapter then looks at the development of functional MRI, and presents a normative approach to decision-making and learning.