Pulse Oximetry

Author(s):  
Patrick Magee ◽  
Mark Tooley

The pulse oximeter is a device for non-invasive, continuous measurement of oxygen saturation. As such it is arguably one of the most important intraoperative monitors at the disposal of anaesthetists, and efforts are being made to make pulse oximeters available at all operating locations throughout the world [Walker et al. 2009]. Although the device measures oxygen saturation of arterial blood, which is the physiological end point of interest, it is not a replacement for monitoring all the events which may lead to hypoxaemia; in other words it does not replace an oxygen analyser at the common gas outlet of the anaesthetic machine. Depending on the site of the probe, usually ear lobe or finger, there is a variable delay between the onset of a causative hypoxaemic event and detection of hypoxaemia by the pulse oximeter, the delay being longer the more peripherally placed is the probe. Appropriate size and design of the probe for accuracy and safety in children is important [Howell et al. 1993] and finger probes are more accurate but slower to respond than ear probes [Webb et al. 1991]. Forehead reflectance probes have been used with good results [Casati et al. 2007]. It is also true that the human eye is notoriously bad at detecting cyanosis in the range of saturations 81–85%. For additional information on Monitoring Principles see Chapter 11. It is clear, however, that in a hierarchy of monitors for anaesthesia, the pulse oximeter is indispensable. A pulse oximeter uses two separate technologies: one is plethysmography, where reproduction of the pulsatile waveform takes place; the other is spectroscopy, where absorption of light of specific wavelengths by body tissues occurs and is analysed. The spectroscopic aspects depend on the laws of Beer and Lambert, which can be combined to state that the amount of light absorbed by a substance is proportional to the thickness of the substance sample (the path length of the light) and the concentration of the substance.

2006 ◽  
Vol 105 (5) ◽  
pp. 892-897 ◽  
Author(s):  
Steven J. Barker ◽  
Jeremy Curry ◽  
Daniel Redford ◽  
Scott Morgan

Background A new eight-wavelength pulse oximeter is designed to measure methemoglobin and carboxyhemoglobin, in addition to the usual measurements of hemoglobin oxygen saturation and pulse rate. This study examines this device's ability to measure dyshemoglobins in human volunteers in whom controlled levels of methemoglobin and carboxyhemoglobin are induced. Methods Ten volunteers breathed 500 ppm carbon monoxide until their carboxyhemoglobin levels reached 15%, and 10 different volunteers received intravenous sodium nitrite, 300 mg, to induce methemoglobin. All were instrumented with arterial cannulas and six Masimo Rad-57 (Masimo Inc., Irvine, CA) pulse oximeter sensors. Arterial blood was analyzed by three laboratory CO-oximeters, and the resulting carboxyhemoglobin and methemoglobin measurements were compared with the corresponding pulse oximeter readings. Results The Rad-57 measured carboxyhemoglobin with an uncertainty of +/-2% within the range of 0-15%, and it measured methemoglobin with an uncertainty of 0.5% within the range of 0-12%. Conclusion The Masimo Rad-57 is the first commercially available pulse oximeter that can measure methemoglobin and carboxyhemoglobin, and it therefore represents an expansion of our oxygenation monitoring capability.


Author(s):  
Aslıhan Gürün Kaya ◽  
Miraç Öz ◽  
İREM AKDEMİR KALKAN ◽  
Ezgi Gülten ◽  
güle AYDIN ◽  
...  

Introduction: Guidelines recommend using a pulse oximeter rather than arterial blood gas (ABG) for COVID-19 patients. However, significant differences can be observed between oxygen saturation measured by pulse oximetry (SpO2) and arterial oxygen saturation (SaO2) in some clinical conditions. We aimed to assess the reliability of pulse oximeter in patients with COVID-19 Methods: We retrospectively reviewed ABG analyses and SpO2 levels measured simultaneously with ABG in patients hospitalized in COVID-19 wards. Results: We categorized total 117 patients into two groups; in whom the difference between SpO2 and SaO2 was 4% (acceptable difference) and >4% (large difference). Large difference group exhibited higher neutrophil count, C-reactive protein, ferritin, fibrinogen, D-dimer and lower lymphocyte count. Multivariate analyses revealed that increased fibrinogen, increased ferritin and decreased lymphocyte count were independent risk factors for large difference between SpO2 and SaO2. The total study group demonstrated the negative bias of 4.02% with the limits of agreement of −9.22% to 1.17%. The bias became significantly higher in patients with higher ferritin, fibrinogen levels and lower lymphocyte count. Conclusion: Pulse oximeters may not be sufficient to assess actual oxygen saturation especially in COVID-19 patients with high ferritin and fibrinogen levels and low lymphocyte count low SpO2 measurements.


Author(s):  
Shiv Prakash Singh

Use of technology in healthcare is growing importance as a result of the tendency to acquire chronic disease like heart attack and high blood pressure. Heart rate and blood oxygen saturation is a couple of such biometrics that is monitored in this project to provide information regarding the health of the body. By measuring the intensity change of light transmitted through tissue due to arterial blood, heart rate is measured. Furthermore, oxygenated blood has different light absorption characteristics than deoxygenated blood under red and infrared wavelengths. Comparing the absorptions produce an estimate of the oxygen saturation of blood. The purpose is to examine how heart rate and the oxygen saturation of subject is measured from finger and then processed and displayed. The design, is small in size, easy to use, allows a non- invasive, real time method to provide information regarding health. This enables an efficient and economical means for managing the health care. This document is intended to be used by engineers, medical equipment developers, anyone related to medical practice and interested in understanding the operation of pulse oximeter and heart rate monitoring system.


Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3457 ◽  
Author(s):  
Ohad Yossef Hay ◽  
Meir Cohen ◽  
Itamar Nitzan ◽  
Yair Kasirer ◽  
Sarit Shahroor-karni ◽  
...  

Oxygen saturation in arterial blood (SaO2) provides information about the performance of the respiratory system. Non-invasive measurement of SaO2 by commercial pulse oximeters (SpO2) make use of photoplethysmographic pulses in the red and infrared regions and utilizes the different spectra of light absorption by oxygenated and de-oxygenated hemoglobin. Because light scattering and optical path-lengths differ between the two wavelengths, commercial pulse oximeters require empirical calibration which is based on SaO2 measurement in extracted arterial blood. They are still prone to error, because the path-lengths difference between the two wavelengths varies among different subjects. We have developed modified pulse oximetry, which makes use of two nearby infrared wavelengths that have relatively similar scattering constants and path-lengths and does not require an invasive calibration step. In measurements performed on adults during breath holding, the two-infrared pulse oximeter and a commercial pulse oximeter showed similar changes in SpO2. The two pulse oximeters showed similar accuracy when compared to SaO2 measurement in extracted arterial blood (the gold standard) performed in intensive care units on newborns and children with an arterial line. Errors in SpO2 because of variability in path-lengths difference between the two wavelengths are expected to be smaller in the two-infrared pulse oximeter.


1988 ◽  
Vol 255 (1) ◽  
pp. E65-E69 ◽  
Author(s):  
H. W. Karl ◽  
E. B. Wolpert ◽  
D. E. Rannels

The effects of preventing the acute hypoxemia common during lung resection on postpneumonectomy lung growth were investigated. Rats that had undergone translaryngeal tracheal intubation and were supported with intermittent positive-pressure ventilation during pneumonectomy (IPPV) were compared with those allowed to breathe room air spontaneously via the natural airway (SV). A pulse oximeter was used to document intraoperative and postoperative oxygen saturation (SaO2). Almost all SV animals became acutely hypoxemic during thoracotomy [SaO2 less than 50% for 2.5 +/- 0.5 min (8/9), less than 30% for 1.7 +/- 0.4 (8/9)], whereas IPPV animals largely maintained oxygenation [SaO2 less than 50% for 0.3 +/- 0.2 min (8/13), less than 30% for 0.05 +/- 0.05 min (1/13)]. Direct measurements of oxygen saturation correlated well with the pulse oximeter (slope of regression line = 0.90, correlation 0.91), and arterial blood gases showed the SV group to be hypercapneic and acidotic as well as hypoxemic during lung removal. These abnormalities resolved soon after chest closure. Intubated animals had mild postextubation hypoxemia that normalized within 3 h of surgery. Two weeks postoperative, there were no differences in lung mass or content of water, RNA, DNA, and protein between the two groups.


2021 ◽  
Vol 30 (11) ◽  
pp. 666-670
Author(s):  
Joanna Shakespeare ◽  
Edward Parkes ◽  
Catherine Gilsenan ◽  
Asad Ali

Pulse oximetry is widely used to assess oxygen saturation (SpO2) in order to guide patient care and monitor the response to treatment. However, inappropriate oximeter probe placement has been shown to affect the measured oximetry values in healthy and normoxic outpatients. This study evaluated how treatment decisions might be impacted by SpO2 values obtained using a finger probe placed on the pinna of the ear in a cohort of 46 patients receiving non-invasive ventilation compared with values obtained from a probe on the finger and the results of arterial blood gas (ABG) (SaO2) analysis. Bland-Altman analysis was performed to evaluate agreement between the methods. Finger probe saturation was not statistically different from SaO2, with a mean difference of -0.66% (P>0.05). Saturation from the ear was significantly different (-4.29%; P<0.001). Subgroup analysis in hypoxic patients (SaO2<90%) showed a significant difference between ABG SaO2, and finger and ear SpO2. The study provides evidence that placement of a finger probe on the ear is unsafe clinical practice, potentially leading to patient mismanagement.


1993 ◽  
Vol 21 (5) ◽  
pp. 558-564 ◽  
Author(s):  
G. L. Ludbrook ◽  
W. J. Russell ◽  
R. K. Webb ◽  
I. D. Klepper ◽  
M. Currie

The first 2000 incidents reported to the Australian Incident Monitoring Study (AIMS) were analysed with respect to the role of the electrocardiograph (ECG). Of these, 138 (7%) were first detected by the ECG. Of the 1256 incidents which occurred in association with general anaesthesia (GA incidents) 48% were “human detected” and 52% “monitor detected”, the ECG was ranked third and detected 121 (19%) of these monitor detected GA incidents. However over 98% of incidents first detected by the ECG were heart rate changes; they would also have been detected by a pulse meter or pulse oximeter which would have supplied additional information about the adequacy of peripheral perfusion. The ECG is a “first-line” monitor in situations with the potential for myocardial ischaemia, complex dysrhythmias or altered myocardial conduction and should be used in all critically ill patients as well as those at significant risk of these problems. The ECG frequently detects incidents involving minor physiological trespass, such as simple heart rate and rhythm changes associated with anaesthetic agents. These incidents are generally detected relatively early in their evolution. AIMS data has confirmed, however, that the ECG has such poor sensitivity for serious physiological changes such as hypoxia, hypercarbia and hypotension that it cannot even be regarded as a useful “back-up” monitor for these problems. Indeed a “normal” ECG in a dangerous situation may lead to a degree of complacency. Because the anaesthetist cannot differentiate between these minor and serious causes of ECG changes, it was decided, for a theoretical analysis, that although the ECG used on its own would have detected 55% of the 1256 GA incidents, had they been allowed to evolve, it could not be assumed that it would do so without potential for organ damage. The ECG may be regarded as an adjunct to, but does not replace, an oxygen analyser, pulse oximeter, capnograph, or high pressure alarm. An ECG should always be available but need not be used for young fit patients unless specifically indicated.


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