Depression in Dementia Syndromes

Author(s):  
Jessica A. Brommelhoff

Depressive symptoms are common in many dementia syndromes, and depressive disorders are much more common in older adults with dementia than in cognitively intact older adults. Depression may be a risk factor for, or a prodromal feature of, subsequent dementia. Several neuropathological mechanisms have been suggested to explain these relationships, including the role of underlying cerebrovascular risk factors for depression and cognitive impairment. Depression also may be present in dementia as an emotional reaction to cognitive decline, or as a recurrence of early and midlife depression. Differential diagnosis between depression and dementia is essential, but complicated by problems in assessment, overlapping symptoms between the two conditions, and other medical co-morbidities. Pharmacological treatment of depression in dementia may also be complicated by medical co-morbidity, and can run the risk for adverse reactions or interactions between medications. Psychotherapy and psychosocial interventions, however, hold some promise for effective reduction of depressive symptoms.

2020 ◽  
Author(s):  
Zhenjie Wang ◽  
Hanmo Yang ◽  
Pianpian Zheng ◽  
Bei Liu ◽  
Zhanyuan Guo ◽  
...  

Abstract Background: Although some studies have reported the association between life negative events and depressive disorders, very limited studies have examined the association between life negative events exposure and depressive symptoms risk among Chinese older adults. Methods : Data were obtained from the China Longitudinal Ageing Social Survey (CLASS), which was a stratified, multi-stage, probabilistic sampling survey, conducted in 2014. General linear regression and logistic regression were used to examine the association between life negative events exposure and depressive symptoms among Chinese older adults. Results: Life negative events showed statistical dose-response association with depressive symptoms risk after adjustment for the confounding factors ( P trend <0.001). Under consideration of life negative events exposure, participants who lived in rural areas, without a spouse or live alone were vulnerable to depressive symptoms. Conclusions: Life negative events played a risk role of depressive symptoms among Chinese older adults, especially among those in rural areas, females or without a spouse. Our current study is valuable for the development of special prevention depressive symptoms programs among elderly individuals, especially those who have experienced negative events.


2020 ◽  
Author(s):  
Zhenjie Wang ◽  
Hanmo Yang ◽  
Pianpian Zheng ◽  
Bei Liu ◽  
Zhanyuan Guo ◽  
...  

Abstract Background: Although some studies have reported the association between life negative events and depressive disorders, very limited studies have examined the association between life negative events exposure and depressive symptoms risk among Chinese older adults.Methods: Data were obtained from the China Longitudinal Ageing Social Survey (CLASS), which was a stratified, multi-stage, probabilistic sampling survey, conducted in 2014. General linear regression and logistic regression were used to examine the association between life negative events exposure and depressive symptoms among Chinese older adults.Results: Life negative events showed statistical dose-response association with depressive symptoms risk after adjustment for the confounding factors (P trend <0.001). Under consideration of life negative events exposure, participants who lived in rural areas, without a spouse or live alone were vulnerable to depressive symptoms.Conclusions: Life negative events played a risk role of depressive symptoms among Chinese older adults, especially among those in rural areas, females or without a spouse. Our current study is valuable for the development of special prevention depressive symptoms programs among elderly individuals, especially those who have experienced negative events.


2020 ◽  
Author(s):  
Zhenjie Wang ◽  
Hanmo Yang ◽  
Pianpian Zheng ◽  
Bei Liu ◽  
Zhanyuan Guo ◽  
...  

Abstract Background Although some studies have reported the association between life negative events and depressive disorders, very limited studies have examined the association between life negative events exposure and depressive symptoms risk among Chinese older adults.Methods : Data were obtained from the China Longitudinal Ageing Social Survey (CLASS) conducted in 2014. General linear regression and logistic regression were used to examine the association between life negative events exposure and depressive symptoms.Results The prevalence of depressive symptoms was 43% among current Chinese old population. Life negative events showed statistical dose-response association with depressive symptoms risk after adjustment for the confounding factors (Ptrend <0.001). Participants who lived in rural areas, without a spouse or live alone were vulnerable to depressive symptoms.Conclusions Life negative events played a risk role of depressive symptoms among Chinese older adults, especially among those in rural areas, females or without a spouse. Our current study is valuable for the development of special prevention depressive symptoms programs among elderly individuals, especially those who have experienced negative events.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 751-751
Author(s):  
Jianyun Wang ◽  
Renyao Zhong ◽  
Yaolin Pei ◽  
Bei Wu

Abstract This study aimed to examine the trajectory of depressive symptoms among Chinese older adults with disabilities and the role of adult children’s support in predicting trajectory classes of depressive symptoms. Data were drawn from three waves of the China Health and Retirement Longitudinal Study (2011-2015). The sample included 1420 disabled older adults age 60+ at the baseline and completed all three waves of the data. Growth mixture model shows two-class depressive symptoms trajectories: the higher risk group (25.49%) and the lower risk group (74.51%). Logistic regression results showed that respondents who received a longer term of adult children’s instrumental support were more likely to be classified in a higher risk group after controlling the covariates (OR=1.184, p&lt;0.05), while financial support and the frequency of contacts were not associated with the increased level of depressive symptoms. The policy implications were also discussed in this study.


2013 ◽  
Vol 23 (3) ◽  
pp. 1039-1043 ◽  
Author(s):  
Gertrudis I. J. M. Kempen ◽  
Adelita V. Ranchor ◽  
Ton Ambergen ◽  
G. A. Rixt Zijlstra

2002 ◽  
Vol 17 (4) ◽  
pp. 222-226 ◽  
Author(s):  
R. Coelho ◽  
A. Martins ◽  
H. Barros

SummaryPurposeDepressive disorders (DD) in adolescence are often misdiagnosed and under-recognised. A major clinical problem regards the high rate of co-morbidity with other disorders, namely substance abuse. The aim of this study was to assess the discriminative power of the Beck Depression Inventory II (BDI-II) to characterise specific social–demographic variables related to DD in adolescence.MethodsA Portuguese version of the BDI-II and a social–demographic questionnaire were administered to 775 Portuguese adolescents (312 males, 463 females; mean age: 16.9 years); 83 adolescents performed a clinical interview following DSM-IV criteria.ResultsMean BDI-II Portuguese version (BDI-II-P) total score was 10.31 (standard deviation: 8.4), with females reporting more depressive symptoms than males (P < 0.001). Low academic achievement, sleep disturbances, and alcohol consumption were consistently associated with depressive symptoms for both genders. Higher tobacco consumption was significantly associated with depressive symptoms in females. Familial factors did not appear to be associated with depressive symptoms in males. However, a higher frequency of siblings, having separated parents as well as a more extreme perception of the mother's educational style were consistently associated with depressive symptoms in females.ConclusionThe BDI-II-P showed discriminative power to characterise social–demographic variables related to DD especially in adolescent females.


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